Carlos Cordon-Cardo

Department of Pathology, Icahn School of Medicine at Mount Sinai

Affiliated withIcahn School of Medicine at Mount Sinai Icahn School of Medicine at Mount Sinai

Research Area

MedicineCancer Research

Biography

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title	2014
Publication title	2015
Publication title	2017
Publication title	2019

Other Publications

Article	Year
Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science (New York, N.Y.)\| PubMed ID: 12750523	2003
Lack of p53 nuclear immunostaining is not indicative of absence of TP53 gene mutations in colorectal adenocarcinomas. Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry\| PubMed ID: 12777996	2003
Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors. Cancer research\| PubMed ID: 12782593	2003
Oncogenes in melanoma. Oncogene\| PubMed ID: 12789285	2003
A multigenic program mediating breast cancer metastasis to bone. Cancer cell\| PubMed ID: 12842083	2003
Altered expression of p27 and Skp2 proteins in prostate cancer of African-American patients. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 12855638	2003
Gene discovery in bladder cancer progression using cDNA microarrays. The American journal of pathology\| PubMed ID: 12875971	2003
Classification and subtype prediction of adult soft tissue sarcoma by functional genomics. The American journal of pathology\| PubMed ID: 12875988	2003
Tumor suppressor role for myopodin in bladder cancer: loss of nuclear expression of myopodin is cell-cycle dependent and predicts clinical outcome. Oncogene\| PubMed ID: 12917631	2003
Adrenocortical adenoma and carcinoma: histopathological and molecular comparative analysis. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 12920217	2003
Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer. Nature medicine\| PubMed ID: 12960962	2003
Tumor promotion by Mdm2 splice variants unable to bind p53. Cancer research\| PubMed ID: 14522887	2003
p73alpha regulation by Chk1 in response to DNA damage. Molecular and cellular biology\| PubMed ID: 14585975	2003
Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia. Blood\| PubMed ID: 14630830	2004
Genetic signatures of differentiation induced by 1alpha,25-dihydroxyvitamin D3 in human colon cancer cells. Cancer research\| PubMed ID: 14633706	2003
Comparison of gene expression profiles in laser-microdissected, nonembedded, and OCT-embedded tumor samples by oligonucleotide microarray analysis. Clinical chemistry\| PubMed ID: 14633888	2003
p73 Expression in human normal and tumor tissues: loss of p73alpha expression is associated with tumor progression in bladder cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 14654547	2003
Pten dose dictates cancer progression in the prostate. PLoS biology\| PubMed ID: 14691534	2003
MDM2 and prognosis. Molecular cancer research : MCR\| PubMed ID: 14757840	2004
Loss of the tumor suppressor PML in human cancers of multiple histologic origins. Journal of the National Cancer Institute\| PubMed ID: 14970276	2004
Histone deacetylase inhibitors: assays to assess effectiveness in vitro and in vivo. Methods in enzymology\| PubMed ID: 14975307	2004
p53 and RB: simple interesting correlates or tumor markers of critical predictive nature? Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 14981108	2004
Application of new in situ hybridization probes for Ku70 and Ku80 in tissue microarrays of paraffin-embedded malignant melanomas: correlation with immunohistochemical analysis. Human pathology\| PubMed ID: 14991539	2004
Decreased retinoid X receptor-alpha protein expression in basal cells occurs in the early stage of human prostate cancer development. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 15006913	2004
Inhibition of orthotopic human bladder tumor growth by lentiviral gene transfer of endostatin. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15014038	2004
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature\| PubMed ID: 15029198	2004
The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. Nature medicine\| PubMed ID: 15098029	2004
Altered expression and new mutations in DNA mismatch repair genes MLH1 and MSH2 in melanoma brain metastases. Anticancer research\| PubMed ID: 15161053	2004
High-resolution characterization of the pancreatic adenocarcinoma genome. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15199222	2004
Hyperphosphorylation of pRb: a mechanism for RB tumour suppressor pathway inactivation in bladder cancer. The Journal of pathology\| PubMed ID: 15221935	2004
Analysis of adenomatous polyposis coli gene expression, APC locus-microsatellite instability and APC promoter methylation in the progression of melanocytic tumours. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 15257316	2004
Comparison of DNA ploidy status and DNA ploidy-related parameters in malignant melanoma tissue microarrays and full sections. Human pathology\| PubMed ID: 15257554	2004
Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation. Nature genetics\| PubMed ID: 15273685	2004
Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer. Molecular cancer therapeutics\| PubMed ID: 15299075	2004
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature\| PubMed ID: 15306814	2004
Cytokeratin positivity in paraffin-embedded malignant melanomas: comparative study of KL1, A4 and Lu5 antibodies. Anticancer research\| PubMed ID: 15510611	2004
Genetic and immunophenotype analyses of TP53 in bladder cancer: TP53 alterations are associated with tumor progression. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 15538112	2004
Glutathione S-transferase P1 Ile105Val polymorphism, cigarette smoking and prostate cancer. Cancer detection and prevention\| PubMed ID: 15542263	2004
Racial disparity of epidermal growth factor receptor expression in prostate cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15570072	2004
Role of Dok-1 and Dok-2 in leukemia suppression. The Journal of experimental medicine\| PubMed ID: 15611295	2004
Application of in situ hybridization probes for MLH-1 and MSH-2 in tissue microarrays of paraffin-embedded malignant melanomas: correlation with immunohistochemistry and tumor stage. Human pathology\| PubMed ID: 15619215	2004
Molecular profiling of tumor progression in head and neck cancer. Archives of otolaryngology--head & neck surgery\| PubMed ID: 15655179	2005
Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature\| PubMed ID: 15662416	2005
Safety and biologic activity of intravenous BCL-2 antisense oligonucleotide (G3139) and taxane chemotherapy in patients with advanced cancer. Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry\| PubMed ID: 15722787	2005
Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15756026	2005
p73beta-Mediated apoptosis requires p57kip2 induction and IEX-1 inhibition. Cancer research\| PubMed ID: 15781630	2005
Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15867226	2005
A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15897584	2005
A microRNA polycistron as a potential human oncogene. Nature\| PubMed ID: 15944707	2005
Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression. Genes & development\| PubMed ID: 16027168	2005
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature\| PubMed ID: 16079851	2005
Cytokeratin expression correlates with aneuploidy in cytological specimens of melanoma metastases. Anticancer research\| PubMed ID: 16080528	2005
Expression of p63 in diffuse large B-cell lymphoma. Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry\| PubMed ID: 16082248	2005
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature\| PubMed ID: 16094360	2005
Gene expression profiling in single cells within tissue. Nature methods\| PubMed ID: 16118636	2005
A novel multiplexing, polymerase chain reaction-based assay for the analysis of chromosome 18q status in colorectal cancer. The Journal of molecular diagnostics : JMD\| PubMed ID: 16237217	2005
Tobacco smoking, GSTP1 polymorphism, and bladder carcinoma. Cancer\| PubMed ID: 16240451	2005
Relationship of nm23 expression to proliferation and prognosis in malignant melanomas of the oral cavity. In vivo (Athens, Greece)\| PubMed ID: 16277028	2005
Proposal of a new grading system for malignant fibrous histiocytomas. Anticancer research\| PubMed ID: 16309231	2005
A novel logistic model based on clinicopathological features predicts microsatellite instability in colorectal carcinomas. Diagnostic molecular pathology : the American journal of surgical pathology, part B\| PubMed ID: 16319691	2005
[Molecular protocol for HER2/neu analysis in breast carcinoma]. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico\| PubMed ID: 16373062	2005
Differential exoprotease activities confer tumor-specific serum peptidome patterns. The Journal of clinical investigation\| PubMed ID: 16395409	2006
Profiling bladder cancer using targeted antibody arrays. The American journal of pathology\| PubMed ID: 16400012	2006
Amplification of CDK4 and MDM2 in malignant melanoma. Genes, chromosomes & cancer\| PubMed ID: 16419059	2006
Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 16432078	2006
Loss of Ku70/Ku80 expression occurs more frequently in hereditary than in sporadic colorectal tumors. Tissue microarray study. Human pathology\| PubMed ID: 16564919	2006
Identification of a tumour suppressor network opposing nuclear Akt function. Nature\| PubMed ID: 16680151	2006
Autocrine PDGFR signaling promotes mammary cancer metastasis. The Journal of clinical investigation\| PubMed ID: 16741576	2006
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell\| PubMed ID: 16814713	2006
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene. Cell\| PubMed ID: 16814714	2006
Altered expression of DNA double-strand repair genes Ku70 and Ku80 in carcinomas of the oral cavity. Anticancer research\| PubMed ID: 16827151	2006
Analysis of DNA mismatch repair gene expression and mutations in thyroid tumours. Anticancer research\| PubMed ID: 16827152	2006
Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. Cancer research\| PubMed ID: 16885364	2006
PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR. Nature\| PubMed ID: 16915281	2006
Evaluation of Ki67, p53 and angiogenesis in patients enrolled in a randomized study of neoadjuvant chemotherapy with or without cystectomy: a Southwest Oncology Group Study. Oncology reports\| PubMed ID: 16969498	2006
Alterations of the retinoblastoma and p16 pathway correlate with promoter methylation in malignant fibrous histiocytomas. Anticancer research\| PubMed ID: 17094467	2006
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer cell\| PubMed ID: 17189715	2007
Technology insight: will systems pathology replace the pathologist? Nature clinical practice. Urology\| PubMed ID: 17211424	2007
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Cell\| PubMed ID: 17218260	2007
Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell\| PubMed ID: 17218261	2007
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature\| PubMed ID: 17251933	2007
Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis. The Journal of clinical investigation\| PubMed ID: 17256055	2007
Relation between human papillomavirus positivity and p16 expression in head and neck carcinomas--a tissue microarray study. Anticancer research\| PubMed ID: 17352245	2007
Role of the chromobox protein CBX7 in lymphomagenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17374722	2007
Molecular alterations associated with bladder cancer progression. Seminars in oncology\| PubMed ID: 17382791	2007
The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. Nature medicine\| PubMed ID: 17496901	2007
A polymorphism in HDM2 (SNP309) associates with early onset in superficial tumors, TP53 mutations, and poor outcome in invasive bladder cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17545525	2007
Prognostic significance of p27Kip1 expression in bladder cancer. BJU international\| PubMed ID: 17555476	2007
Improved prediction of prostate cancer recurrence through systems pathology. The Journal of clinical investigation\| PubMed ID: 17557117	2007
Tissue-specific and reversible RNA interference in transgenic mice. Nature genetics\| PubMed ID: 17572676	2007
Highly efficient gene delivery for bladder cancers by intravesically administered replication-competent retroviral vectors. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 17671137	2007
Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer. Cancer research\| PubMed ID: 17671177	2007
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nature medicine\| PubMed ID: 17873882	2007
Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17921246	2007
Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1). The EMBO journal\| PubMed ID: 17948060	2007
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway. The Journal of clinical investigation\| PubMed ID: 17948129	2007
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer cell\| PubMed ID: 21840483	2011
Genomic and proteomic profiles reveal the association of gelsolin to TP53 status and bladder cancer progression. The American journal of pathology\| PubMed ID: 17982131	2007
Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa. International journal of radiation oncology, biology, physics\| PubMed ID: 18191336	2008
A context dependent role for Wnt signaling in tumorigenesis and stem cells. Cell cycle (Georgetown, Tex.)\| PubMed ID: 18239459	2008
TREK-1 is a novel molecular target in prostate cancer. Cancer research\| PubMed ID: 18281496	2008
A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. The American journal of pathology\| PubMed ID: 18310505	2008
Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas. Cancer research\| PubMed ID: 18381430	2008
DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes & development\| PubMed ID: 18519636	2008
Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage. Molecular cell\| PubMed ID: 18614044	2008
Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events. Genes & development\| PubMed ID: 18708577	2008
Systems pathology approach for the prediction of prostate cancer progression after radical prostatectomy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 18711180	2008
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. The Journal of clinical investigation\| PubMed ID: 18725989	2008
Molecular alterations associated with bladder cancer initiation and progression. Scandinavian journal of urology and nephrology. Supplementum\| PubMed ID: 18815930	2008
Associations between variants of the 8q24 chromosome and nine smoking-related cancer sites. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 18990762	2008
Alveolar rhabdomyosarcoma: is the cell of origin a mesenchymal stem cell? Cancer letters\| PubMed ID: 19008039	2009
Comparison of models to predict clinical failure after radical prostatectomy. Cancer\| PubMed ID: 19025977	2009
p53 is localized to a sub-nucleolar compartment after proteasomal inhibition in an energy-dependent manner. Journal of cell science\| PubMed ID: 19033390	2008
Identification of PMF1 methylation in association with bladder cancer progression. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19088041	2008
Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia. Nature medicine\| PubMed ID: 19098907	2009
Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Science signaling\| PubMed ID: 19176516	2009
ETS rearrangements and prostate cancer initiation. Nature\| PubMed ID: 19212347	2009
Correlation of MR imaging and MR spectroscopic imaging findings with Ki-67, phospho-Akt, and androgen receptor expression in prostate cancer. Radiology\| PubMed ID: 19244047	2009
Inactivation of p53 and Pten promotes invasive bladder cancer. Genes & development\| PubMed ID: 19261747	2009
A systems pathology model for predicting overall survival in patients with refractory, advanced non-small-cell lung cancer treated with gefitinib. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 19272767	2009
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nature genetics\| PubMed ID: 19396168	2009
Prediction of prostate cancer recurrence using magnetic resonance imaging and molecular profiles. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19435838	2009
Personalized prediction of tumor response and cancer progression on prostate needle biopsy. The Journal of urology\| PubMed ID: 19450827	2009
Cyfip1 is a putative invasion suppressor in epithelial cancers. Cell\| PubMed ID: 19524508	2009
Systems pathology: a paradigm shift in the practice of diagnostic and predictive pathology. Cancer\| PubMed ID: 19544549	2009
3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma. Cancer research\| PubMed ID: 19602588	2009
Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease. BJU international\| PubMed ID: 19624594	2010
MFH classification: differentiating undifferentiated pleomorphic sarcoma in the 21st Century. Expert review of anticancer therapy\| PubMed ID: 19671033	2009
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Developmental cell\| PubMed ID: 19686682	2009
Intravesical delivery of rapamycin suppresses tumorigenesis in a mouse model of progressive bladder cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 19952358	2009
Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20008839	2010
miR-19 is a key oncogenic component of mir-17-92. Genes & development\| PubMed ID: 20008935	2009
Single nucleotide polymorphisms of 8 inflammation-related genes and their associations with smoking-related cancers. International journal of cancer. Journal international du cancer\| PubMed ID: 20112337	2010
PHF6 mutations in T-cell acute lymphoblastic leukemia. Nature genetics\| PubMed ID: 20228800	2010
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature\| PubMed ID: 20237562	2010
Galectin-3 expression is associated with bladder cancer progression and clinical outcome. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 20401558	2010
Associations between NBS1 polymorphisms, haplotypes and smoking-related cancers. Carcinogenesis\| PubMed ID: 20478923	2010
Integrative genome comparison of primary and metastatic melanomas. PloS one\| PubMed ID: 20520718	2010
Molecular pathways of urothelial development and bladder tumorigenesis. Urologic oncology\| PubMed ID: 20610278	2010
Impact of stromal sensitivity on radiation response of tumors implanted in SCID hosts revisited. Cancer research\| PubMed ID: 20924105	2010
Association of nuclear localization of a long interspersed nuclear element-1 protein in breast tumors with poor prognostic outcomes. Genes & cancer\| PubMed ID: 20948976	2010
The TLX1 oncogene drives aneuploidy in T cell transformation. Nature medicine\| PubMed ID: 20972433	2010
Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer research\| PubMed ID: 21189328	2011
Hydrophilic agarose macrobead cultures select for outgrowth of carcinoma cell populations that can restrict tumor growth. Cancer research\| PubMed ID: 21266362	2011
Three-dimensional culture of mouse renal carcinoma cells in agarose macrobeads selects for a subpopulation of cells with cancer stem cell or cancer progenitor properties. Cancer research\| PubMed ID: 21266363	2011
CpG ODN, Toll like receptor (TLR)-9 agonist, inhibits metastatic colon adenocarcinoma in a murine hepatic tumor model. The Journal of surgical research\| PubMed ID: 21324492	2012
Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression. The American journal of pathology\| PubMed ID: 21356385	2011
Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico\| PubMed ID: 21421465	2011
KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients. The American journal of pathology\| PubMed ID: 21683672	2011
A comparison of the outcomes of neoadjuvant and adjuvant chemotherapy for clinical T2-T4aN0-N2M0 bladder cancer. Cancer\| PubMed ID: 21717438	2012
A systems-based modelling approach using transurethral resection of the prostate (TURP) specimens yielded incremental prognostic significance to Gleason when predicting long-term outcome in ... BJU international\| PubMed ID: 21733075	2012
Postoperative systems models more accurately predict risk of significant disease progression than standard risk groups and a 10-year postoperative nomogram: potential impact on the receipt o... BJU international\| PubMed ID: 21771247	2012
A Role for PML in Innate Immunity. Genes & cancer\| PubMed ID: 21779477	2011
Predictive value of microtubule associated proteins tau and stathmin in patients with nonmuscle invasive bladder cancer receiving adjuvant intravesical taxane therapy. The Journal of urology\| PubMed ID: 21944130	2011
Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool. Acta cirúrgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia\| PubMed ID: 22030824	2011
Personalized approach to prostate cancer prognosis. Archivos españoles de urología\| PubMed ID: 22052759	2011
PPARγ agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma. The Journal of clinical investigation\| PubMed ID: 22293175	2012
Mouse models of human bladder cancer as a tool for drug discovery. Current protocols in pharmacology / editorial board, S.J. Enna (editor-in-chief) ... [et al.]\| PubMed ID: 22294368	2010
PAX7-FKHR fusion gene inhibits myogenic differentiation via NF-kappaB upregulation. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico\| PubMed ID: 22374423	2012
miR-143, miR-222, and miR-452 are useful as tumor stratification and noninvasive diagnostic biomarkers for bladder cancer. The American journal of pathology\| PubMed ID: 22426337	2012
Perioperative polyphenon E, a green tea extract, does not affect the wound complication rate in mice after sham laparotomy yet has an inhibitory effect on wound healing. Surgical innovation\| PubMed ID: 22431911	2012
Translocation renal cell carcinomas in adults: a single-institution experience. The American journal of surgical pathology\| PubMed ID: 22446944	2012
A BAC-based transgenic mouse specifically expresses an inducible Cre in the urothelium. PloS one\| PubMed ID: 22496911	2012
Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia. Molecular cancer therapeutics\| PubMed ID: 22504949	2012
Targeting nonclassical oncogenes for therapy in T-ALL. Cancer cell\| PubMed ID: 22516257	2012
Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells. Cancer cell\| PubMed ID: 22975379	2012
MAGE-A3 is highly expressed in a subset of colorectal cancer patients. Cancer immunity\| PubMed ID: 23390371	2012
A common MicroRNA signature consisting of miR-133a, miR-139-3p, and miR-142-3p clusters bladder carcinoma in situ with normal umbrella cells. The American journal of pathology\| PubMed ID: 23410519	2013
Predicting high-risk disease using tissue biomarkers. Current opinion in urology\| PubMed ID: 23478499	2013
Compound In Vivo Inactivation of Pml and p53 Uncovers a Functional Interaction in Angiosarcoma Suppression. Genes & cancer\| PubMed ID: 23486996	2012
Loss of PML cooperates with mutant p53 to drive more aggressive cancers in a gender-dependent manner. Cell cycle (Georgetown, Tex.)\| PubMed ID: 23656786	2013
Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling. The American journal of pathology\| PubMed ID: 23708211	2013
A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer. Nature genetics\| PubMed ID: 23727860	2013
Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion. Nature genetics\| PubMed ID: 23727861	2013
Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Cancer cell\| PubMed ID: 24291004	2013
RapidCaP, a Novel GEM Model for Metastatic Prostate Cancer Analysis and Therapy, Reveals Myc as a Driver of Pten-Mutant Metastasis. Cancer discovery\| PubMed ID: 24444712	2014
Genomic analysis in active surveillance: predicting high-risk disease using tissue biomarkers. Current opinion in urology\| PubMed ID: 24625431	2014
The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. Genes & development\| PubMed ID: 24636986	2014
Defining the role of CD2 in disease progression and overall survival among patients with completely resected stage-II to -III cutaneous melanoma. Journal of the American Academy of Dermatology\| PubMed ID: 24698703	2014
FBXW7 mutations in melanoma and a new therapeutic paradigm. Journal of the National Cancer Institute\| PubMed ID: 24838835	2014
Characterization of desmoglein expression in the normal prostatic gland. Desmoglein 2 is an independent prognostic factor for aggressive prostate cancer. PloS one\| PubMed ID: 24896103	2014
A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia. Nature medicine\| PubMed ID: 25194570	2014
Bladder cancers arise from distinct urothelial sub-populations. Nature cell biology\| PubMed ID: 25218638	2014
The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells. Molecular and cellular biology\| PubMed ID: 25266660	2014
Overcoming tumor heterogeneity in the molecular diagnosis of urological cancers. Expert review of molecular diagnostics\| PubMed ID: 25327491	2014
Biomarkers for bladder cancer management: present and future. American journal of clinical and experimental urology\| PubMed ID: 25374904	2014
ΔNp63 expression is a protective factor of progression in clinical high grade T1 bladder cancer. The Journal of urology\| PubMed ID: 25444981	2015
Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria. The American journal of pathology\| PubMed ID: 25529796	2015
Limited miR-17-92 overexpression drives hematologic malignancies. Leukemia research\| PubMed ID: 25597017	2015
Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. Nature communications\| PubMed ID: 25608663	2015
A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells. Cancer discovery\| PubMed ID: 25614485	2015
Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis. Cancer discovery\| PubMed ID: 25653093	2015
A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer. Cancer cell\| PubMed ID: 25670080	2015
Methodological aspects of the molecular and histological study of prostate cancer: focus on PTEN. Methods (San Diego, Calif.)\| PubMed ID: 25697760	2015
MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer discovery\| PubMed ID: 25829425	2015
PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer. Cancer medicine\| PubMed ID: 26033689	2015
Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancers. Genes & development\| PubMed ID: 26227964	2015
Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target. Oncoscience\| PubMed ID: 26244168	2015
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia. Nature medicine\| PubMed ID: 26390244	2015
H-RAS mutation is a key molecular feature of pediatric urothelial bladder cancer. A detailed report of three cases. Journal of pediatric urology\| PubMed ID: 26522772	2016
Immunopathologic Assessment of PTEN Expression. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27033068	2016
Enrichment of Cells with Cancer Stem Cell-Like Markers in Relapses of Chemoresistant Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma. Oncology\| PubMed ID: 27077749	2016
Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition. European urology\| PubMed ID: 27178450	2016
The metabolic co-regulator PGC1α suppresses prostate cancer metastasis. Nature cell biology\| PubMed ID: 27214280	2016
Protein Profiling of Bladder Urothelial Cell Carcinoma. PloS one\| PubMed ID: 27626805	2016
Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling. The American journal of pathology\| PubMed ID: 27770613	2016
The role of GATA2 in lethal prostate cancer aggressiveness. Nature reviews. Urology\| PubMed ID: 27872477	2017
Reappraising hyalinizing clear cell carcinoma: A population-based study with molecular confirmation. Head & neck\| PubMed ID: 27898192	2017
Implementation of a Precision Pathology Program Focused on Oncology-Based Prognostic and Predictive Outcomes. Molecular diagnosis & therapy\| PubMed ID: 28000172	2017
The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. The Journal of cell biology\| PubMed ID: 28193700	2017
miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy. Genes & development\| PubMed ID: 28404630	2017
Targeting sarcoma tumor-initiating cells through differentiation therapy. Stem cell research\| PubMed ID: 28433655	2017
PTEN counteracts FBXL2 to promote IP3R3- and Ca(2+)-mediated apoptosis limiting tumour growth. Nature\| PubMed ID: 28614300	2017
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer. Nature\| PubMed ID: 28658205	2017
Erratum: The metabolic co-regulator PGC1α suppresses prostate cancer metastasis. Nature cell biology\| PubMed ID: 28659639	2017
Myocardial Amyloid Quantification with Look-Locker Magnetic Resonance Sequence in Cardiac Amyloidosis. Diagnostic Accuracy in Clinical Practice and Histological Validation. Journal of cardiac failure\| PubMed ID: 28801077	2017