Willi Jahnen-Dechent

Institute for Biomedical Engineering - Biointerface Laboratory, RWTH Aachen University

Research Area

BioengineeringBiochemistry

Biography

Willi Jahnen-Dechent has not added Biography.
If you are Willi Jahnen-Dechent and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2015
Publication title	2022

Other Publications

Article	Year
Erratum for Maler et al., "Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages". mBio\| PubMed ID: 28951479	2017
Systemic inhibition of spontaneous calcification by the serum protein alpha 2-HS glycoprotein/fetuin. Zeitschrift fur Kardiologie\| PubMed ID: 11374033	2001
alpha 2-HS glycoprotein/fetuin, a transforming growth factor-beta/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling. The Journal of biological chemistry\| PubMed ID: 11901155	2002
Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene. Diabetes\| PubMed ID: 12145157	2002
Novel insights into uremic vascular calcification: role of matrix Gla protein and alpha-2-Heremans Schmid glycoprotein/fetuin. Blood purification\| PubMed ID: 12207096	2002
Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2. International immunopharmacology\| PubMed ID: 12489801	2002
Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles. The Journal of biological chemistry\| PubMed ID: 12556469	2003
Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study. Lancet\| PubMed ID: 12642050	2003
Deficiencies of calcium-regulatory proteins in dialysis patients: a novel concept of cardiovascular calcification in uremia. Kidney international. Supplement\| PubMed ID: 12694317	2003
Modulation of angiogenic functions in human macrophages by biomaterials. Biomaterials\| PubMed ID: 12809767	2003
The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification. The Journal of clinical investigation\| PubMed ID: 12897203	2003
Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A. The Biochemical journal\| PubMed ID: 12943536	2003
Functional expression of HGF and HGF receptor/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair, and wound healing. Stem cells (Dayton, Ohio)\| PubMed ID: 15153617	2004
Alpha 2-HS glycoprotein (fetuin-A) modulates murine skin tumorigenesis. International journal of oncology\| PubMed ID: 15254728	2004
alpha2HS-glycoprotein, an antagonist of transforming growth factor beta in vivo, inhibits intestinal tumor progression. Cancer research\| PubMed ID: 15374947	2004
Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated ... Journal of the American Society of Nephrology : JASN\| PubMed ID: 15504939	2004
In vitro behavior of a porous TiO2/perlite composite and its surface modification with fibronectin. Biomaterials\| PubMed ID: 15603777	2005
The serum glycoprotein fetuin-A promotes Lewis lung carcinoma tumorigenesis via adhesive-dependent and adhesive-independent mechanisms. Cancer research\| PubMed ID: 15695392	2005
Do not be misguided by guidelines: the calcium x phosphate product can be a Trojan horse. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 15728269	2005
Role of calcification inhibitors in the pathogenesis of vascular calcification in chronic kidney disease (CKD). Kidney international\| PubMed ID: 15882271	2005
Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification. Journal of the American Society of Nephrology : JASN\| PubMed ID: 16093453	2005
Fetuin-A, a hepatocyte-specific protein that binds Plasmodium berghei thrombospondin-related adhesive protein: a potential role in infectivity. Infection and immunity\| PubMed ID: 16113307	2005
The effect of surface modification of a porous TiO2/perlite composite on the ingrowth of bone tissue in vivo. Biomaterials\| PubMed ID: 16139880	2006
Myocardial stiffness, cardiac remodeling, and diastolic dysfunction in calcification-prone fetuin-A-deficient mice. Journal of the American Society of Nephrology : JASN\| PubMed ID: 16177000	2005
CCAAT enhancer binding protein beta and hepatocyte nuclear factor 3beta are necessary and sufficient to mediate dexamethasone-induced up-regulation of alpha2HS-glycoprotein/fetuin-A gene exp... Journal of molecular endocrinology\| PubMed ID: 16595698	2006
Proteolytic processing by matrix metalloproteinases and phosphorylation by protein kinase CK2 of fetuin-A, the major globulin of fetal calf serum. Biochimie\| PubMed ID: 17110014	2007
Fetuin-A (AHSG) prevents extraosseous calcification induced by uraemia and phosphate challenge in mice. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 17389622	2007
Vascular calcification and fetuin-A deficiency in chronic kidney disease. Trends in cardiovascular medicine\| PubMed ID: 17482094	2007
Assessment of stem cell/biomaterial combinations for stem cell-based tissue engineering. Biomaterials\| PubMed ID: 17935776	2008
Size-dependent cytotoxicity of gold nanoparticles. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 17963284	2007
Mineral chaperones: a role for fetuin-A and osteopontin in the inhibition and regression of pathologic calcification. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 18080808	2008
Hierarchical role of fetuin-A and acidic serum proteins in the formation and stabilization of calcium phosphate particles. The Journal of biological chemistry\| PubMed ID: 18364352	2008
Histidine-rich glycoprotein protects from systemic Candida infection. PLoS pathogens\| PubMed ID: 18797515	2008
Function follows form: shape complementarity and nanoparticle toxicity. Nanomedicine (London, England)\| PubMed ID: 18817462	2008
A shielding topology stabilizes the early stage protein-mineral complexes of fetuin-A and calcium phosphate: a time-resolved small-angle X-ray study. Chembiochem : a European journal of chemical biology\| PubMed ID: 19222044	2009
Type 3 cystatins; fetuins, kininogen and histidine-rich glycoprotein. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 19273244	2009
Fetuin-A protects against atherosclerotic calcification in CKD. Journal of the American Society of Nephrology : JASN\| PubMed ID: 19389852	2009
Secretion of fibrinolytic enzymes facilitates human mesenchymal stem cell invasion into fibrin clots. Cells, tissues, organs\| PubMed ID: 19390164	2010
Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 19642089	2009
The physiologic development of fetuin-a serum concentrations in children. Pediatric research\| PubMed ID: 19690510	2009
Sevelamer and the bone-vascular axis in chronic kidney disease: bone turnover, inflammation, and calcification regulation. Kidney international. Supplement\| PubMed ID: 19946324	2009
Peripheral administration of fetuin-A attenuates early cerebral ischemic injury in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 19953099	2010
Serological cardiovascular and mortality risk predictors in dialysis patients receiving sevelamer: a prospective study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 20172849	2010
Fetuin-A and cystatin C are endogenous inhibitors of human meprin metalloproteases. Biochemistry\| PubMed ID: 20806899	2010
Fetuin-A is a mineral carrier protein: small angle neutron scattering provides new insight on Fetuin-A controlled calcification inhibition. Biophysical journal\| PubMed ID: 21156141	2010
Enhanced platelet activation mediates the accelerated angiogenic switch in mice lacking histidine-rich glycoprotein. PloS one\| PubMed ID: 21264222	2011
A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation. PloS one\| PubMed ID: 21347455	2011
Impact of sirolimus, tacrolimus and mycophenolate mofetil on osteoclastogenesis--implications for post-transplantation bone disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 21622987	2011
Fetuin-A regulation of calcified matrix metabolism. Circulation research\| PubMed ID: 21659653	2011
Exposure to uremic serum induces a procalcific phenotype in human mesenchymal stem cells. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21680902	2011
A red herring in vascular calcification: 'nanobacteria' are protein-mineral complexes involved in biomineralization. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 21965584	2011
Compatibility of different polymers for cord blood-derived hematopoietic progenitor cells. Journal of materials science. Materials in medicine\| PubMed ID: 22071984	2012
Effect of vitamin K2 supplementation on functional vitamin K deficiency in hemodialysis patients: a randomized trial. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 22169620	2012
A fluorescent method to determine vitamin K-dependent gamma-glutamyl carboxylase activity. Analytical biochemistry\| PubMed ID: 22210513	2012
Cytotoxicity of gold nanoparticles. Methods in enzymology\| PubMed ID: 22568908	2012
Ex vivo expansion of cord blood-CD34(+) cells using IGFBP2 and Angptl-5 impairs short-term lymphoid repopulation in vivo. Journal of tissue engineering and regenerative medicine\| PubMed ID: 22653714	2013
Two-dimensional polymer-based cultures expand cord blood-derived hematopoietic stem cells and support engraftment of NSG mice. Tissue engineering. Part C, Methods\| PubMed ID: 22712684	2013
Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A. Circulation research\| PubMed ID: 22753077	2012
Cord blood-hematopoietic stem cell expansion in 3D fibrin scaffolds with stromal support. Biomaterials\| PubMed ID: 22800538	2012
Context dependent role of the CD36--thrombospondin--histidine-rich glycoprotein axis in tumor angiogenesis and growth. PloS one\| PubMed ID: 22808089	2012
Fetuin-A function in systemic mineral metabolism. Trends in cardiovascular medicine\| PubMed ID: 22902178	2012
Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype. PloS one\| PubMed ID: 22952653	2012
Nanoparticle-based test measures overall propensity for calcification in serum. Journal of the American Society of Nephrology : JASN\| PubMed ID: 22956818	2012
Accelerated growth plate mineralization and foreshortened proximal limb bones in fetuin-A knockout mice. PloS one\| PubMed ID: 23091616	2012
Fetuin-a in the developing brain. Developmental neurobiology\| PubMed ID: 23109215	2013
Embryonic stem cell-derived M2-like macrophages delay cutaneous wound healing. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society\| PubMed ID: 23126541	2013
High-sensitivity real-time analysis of nanoparticle toxicity in green fluorescent protein-expressing zebrafish. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 23143852	2013
Novel insights into osteogenesis and matrix remodelling associated with calcific uraemic arteriolopathy. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 23223222	2013
The role of fetuin-A in physiological and pathological mineralization. Calcified tissue international\| PubMed ID: 23277412	2013
Fluorescent SNAP-tag galectin fusion proteins as novel tools in glycobiology. Current pharmaceutical design\| PubMed ID: 23431989	2013
Fetuin-B, a liver-derived plasma protein is essential for fertilization. Developmental cell\| PubMed ID: 23562279	2013
Differential hERG ion channel activity of ultrasmall gold nanoparticles. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23630249	2013
Molecularly stabilised ultrasmall gold nanoparticles: synthesis, characterization and bioactivity. Nanoscale\| PubMed ID: 23743952	2013
HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment. Angiogenesis\| PubMed ID: 23793459	2013
Hepatocyte growth factor-loaded biomaterials for mesenchymal stem cell recruitment. Stem cells international\| PubMed ID: 23861688	2013
Warfarin induces cardiovascular damage in mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 23990204	2013
Biofabrication under fluorocarbon: a novel freeform fabrication technique to generate high aspect ratio tissue-engineered constructs. BioResearch open access\| PubMed ID: 24083093	2013
In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay. Journal of materials chemistry. B, Materials for biology and medicine\| PubMed ID: 24179674	2013
Cell surface serine protease matriptase-2 suppresses fetuin-A/AHSG-mediated induction of hepcidin. Biological chemistry\| PubMed ID: 25205713	2015
Mammalian gamete fusion depends on the inhibition of ovastacin by fetuin-B. Biological chemistry\| PubMed ID: 25205729	2014
Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein. Blood\| PubMed ID: 25691157	2015
Cytotoxicity of Ultrasmall Gold Nanoparticles on Planktonic and Biofilm Encapsulated Gram-Positive Staphylococci. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 25712910	2015
Analysis of Ebola Virus Entry Into Macrophages. The Journal of infectious diseases\| PubMed ID: 25877552	2015
Calcification Propensity and Survival among Renal Transplant Recipients. Journal of the American Society of Nephrology : JASN\| PubMed ID: 25925688	2015
Association of high fetuin-B concentrations in serum with fertilization rate in IVF: a cross-sectional pilot study. Human reproduction (Oxford, England)\| PubMed ID: 26759143	2016
Letter to the Editor, concerning: "FGF23-regulated production of fetuin-A (AHSG) in osteocytes". Bone\| PubMed ID: 27260648	2016
Down-regulation of the liver-derived plasma protein fetuin-B mediates reversible female infertility. Molecular human reproduction\| PubMed ID: 27733488	2017
Recombinant fetuin-B protein maintains high fertilization rate in cumulus cell-free mouse oocytes. Molecular human reproduction\| PubMed ID: 27733489	2017
Latent TGF-β binding protein-1 deficiency decreases female fertility. Biochemical and biophysical research communications\| PubMed ID: 27956181	2017
Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 28104608	2017
Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice. PloS one\| PubMed ID: 29088242	2017
Histidine-rich glycoprotein-induced vascular normalization improves EPR-mediated drug targeting to and into tumors. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 29730154	2018
Targeting and Modulation of Liver Myeloid Immune Cells by Hard-Shell Microbubbles. Advanced biosystems\| PubMed ID: 29876517	2018
Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity. Frontiers in immunology\| PubMed ID: 30233585	2018
Phosphate, Calcification in Blood, and Mineral Stress: The Physiologic Blood Mineral Buffering System and Its Association with Cardiovascular Risk. International journal of nephrology\| PubMed ID: 30245880	2018
Fetuin-A protein distribution in mature inflamed and ischemic brain tissue. PloS one\| PubMed ID: 30412582	2018
Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases. Scientific reports\| PubMed ID: 30679641	2019
Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition. IUCrJ\| PubMed ID: 30867929	2019
The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases. Scientific reports\| PubMed ID: 31604990	2019
Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nature immunology\| PubMed ID: 31819254	2020
Lumenal calcification and microvasculopathy in fetuin-A-deficient mice lead to multiple organ morbidity. PloS one\| PubMed ID: 32074120	2020
Microvasculopathy and soft tissue calcification in mice are governed by fetuin-A, magnesium and pyrophosphate. PloS one\| PubMed ID: 32074140	2020
Nature's remedy to phosphate woes: calciprotein particles regulate systemic mineral metabolism. Kidney international\| PubMed ID: 32200857	2020
Rapid calcification propensity testing in blood using a temperature controlled microfluidic polymer chip. PloS one\| PubMed ID: 32255786	2020
Calciprotein particles: mineral behaving badly? Current opinion in nephrology and hypertension\| PubMed ID: 32404635	2020
Mud in the blood: the role of protein-mineral complexes and extracellular vesicles in biomineralisation and calcification. Journal of structural biology\| PubMed ID: 32711043	2020
Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress. Nature communications\| PubMed ID: 33483479	2021
Limited proteolysis by acrosin affects sperm-binding and mechanical resilience of the mouse zona pellucida. Molecular human reproduction\| PubMed ID: 33779727	2021
Live Imaging of Calciprotein Particle Clearance and Receptor Mediated Uptake: Role of Calciprotein Monomers. Frontiers in cell and developmental biology\| PubMed ID: 33996793	2021
Interleukin-1α Is a Central Regulator of Leukocyte-Endothelial Adhesion in Myocardial Infarction and in Chronic Kidney Disease. Circulation\| PubMed ID: 34192892	2021
The E-modulus of the oocyte is a non-destructive measure of zona pellucida hardening. Reproduction (Cambridge, England)\| PubMed ID: 34320465	2021
Development of the BioHybrid Assay: Combining Primary Human Vascular Smooth Muscle Cells and Blood to Measure Vascular Calcification Propensity. Cells\| PubMed ID: 34440866	2021