Ali Khademhosseini

Harvard-MIT Division of Health Sciences and Technology, Brigham and Women's Hospital

Affiliated withBrigham and Women's Hospital

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title	2007
Publication title	2007
Publication title	2007

Other Publications

Article	Year
A simple soft lithographic route to fabrication of poly(ethylene glycol) microstructures for protein and cell patterning. Biomaterials\| PubMed ID: 14585705	2004
Layer-by-layer deposition of hyaluronic acid and poly-L-lysine for patterned cell co-cultures. Biomaterials\| PubMed ID: 15020132	2004
A soft lithographic approach to fabricate patterned microfluidic channels. Analytical chemistry\| PubMed ID: 15228340	2004
Single nanocrystal arrays on patterned poly(ethylene glycol) copolymer microstructures using selective wetting and drying. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 15248685	2004
Patterning and separating infected bacteria using host-parasite and virus-antibody interactions. Biomedical microdevices\| PubMed ID: 15377832	2004
Molded polyethylene glycol microstructures for capturing cells within microfluidic channels. Lab on a chip\| PubMed ID: 15472725	2004
Characterization of chemisorbed hyaluronic acid directly immobilized on solid substrates. Journal of biomedical materials research. Part B, Applied biomaterials\| PubMed ID: 15486967	2005
Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer research\| PubMed ID: 15520166	2004
Fabrication of gradient hydrogels using a microfluidics/photopolymerization process. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 15986641	2004
Microfluidic system for studying the interaction of nanoparticles and microparticles with cells. Analytical chemistry\| PubMed ID: 16131052	2005
Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components. Biomaterials\| PubMed ID: 16242769	2006
Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro. Stem cells (Dayton, Ohio)\| PubMed ID: 16253980	2006
Chips to Hits: microarray and microfluidic technologies for high-throughput analysis and drug discovery. September 12-15, 2005, MA, USA. Expert review of molecular diagnostics\| PubMed ID: 16255625	2005
Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays. Lab on a chip\| PubMed ID: 16286969	2005
Magnetically responsive polymeric microparticles for oral delivery of protein drugs. Pharmaceutical research\| PubMed ID: 16388405	2006
Conformal coating of mammalian cells immobilized onto magnetically driven beads. Tissue engineering\| PubMed ID: 16411825	2005
Microscale technologies for tissue engineering and biology. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16477028	2006
Direct confinement of individual viruses within polyethylene glycol (PEG) nanowells. Nano letters\| PubMed ID: 16771579	2006
Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment. Journal of biomedical materials research. Part A\| PubMed ID: 16788972	2006
Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures. Biomaterials\| PubMed ID: 16814859	2006
Micromolding of shape-controlled, harvestable cell-laden hydrogels. Biomaterials\| PubMed ID: 16828863	2006
Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates. Biomaterials\| PubMed ID: 16901537	2006
Enhanced angiogenesis through controlled release of basic fibroblast growth factor from peptide amphiphile for tissue regeneration. Biomaterials\| PubMed ID: 16930687	2006
Drug delivery systems in urology--getting "smarter". Urology\| PubMed ID: 17010721	2006
Fabrication of non-biofouling polyethylene glycol micro- and nanochannels by ultraviolet-assisted irreversible sealing. Lab on a chip\| PubMed ID: 17066166	2006
A controlled-release strategy for the generation of cross-linked hydrogel microstructures. Journal of the American Chemical Society\| PubMed ID: 17117838	2006
Bone morphogenetic protein-4 enhances cardiomyocyte differentiation of cynomolgus monkey ESCs in knockout serum replacement medium. Stem cells (Dayton, Ohio)\| PubMed ID: 17138962	2007
Microfluidic patterning for fabrication of contractile cardiac organoids. Biomedical microdevices\| PubMed ID: 17146728	2007
Interplay of biomaterials and micro-scale technologies for advancing biomedical applications. Journal of biomaterials science. Polymer edition\| PubMed ID: 17176747	2006
Bone regeneration through controlled release of bone morphogenetic protein-2 from 3-D tissue engineered nano-scaffold. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 17207881	2007
A cell-laden microfluidic hydrogel. Lab on a chip\| PubMed ID: 17538718	2007
Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab on a chip\| PubMed ID: 17538722	2007
Quantitative analysis of cell adhesion on aligned micro- and nanofibers. Journal of biomedical materials research. Part A\| PubMed ID: 17607759	2008
DNA nanoparticles encapsulated in 3D tissue-engineered scaffolds enhance osteogenic differentiation of mesenchymal stem cells. Journal of biomedical materials research. Part A\| PubMed ID: 17688252	2008
Microengineered hydrogels for tissue engineering. Biomaterials\| PubMed ID: 17707502	2007
Reusable, reversibly sealable parylene membranes for cell and protein patterning. Journal of biomedical materials research. Part A\| PubMed ID: 17729252	2008
Generation of static and dynamic patterned co-cultures using microfabricated parylene-C stencils. Lab on a chip\| PubMed ID: 17896010	2007
Cell and protein compatibility of parylene-C surfaces. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 17915896	2007
Covalent immobilization of p-selectin enhances cell rolling. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 17949112	2007
A microwell array system for stem cell culture. Biomaterials\| PubMed ID: 18001830	2008
The use of charge-coupled polymeric microparticles and micromagnets for modulating the bioavailability of orally delivered macromolecules. Biomaterials\| PubMed ID: 18082254	2008
Microfluidics for drug discovery and development: from target selection to product lifecycle management. Drug discovery today\| PubMed ID: 18190858	2008
Microcirculation within grooved substrates regulates cell positioning and cell docking inside microfluidic channels. Lab on a chip\| PubMed ID: 18432345	2008
Microfabricated multilayer parylene-C stencils for the generation of patterned dynamic co-cultures. Journal of biomedical materials research. Part A\| PubMed ID: 18442109	2008
Microfluidic chip-based fabrication of PLGA microfiber scaffolds for tissue engineering. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 18512874	2008
WITHDRAWN: Microfabrication-based engineering of the embryonic and adult stem cell niches. Biomaterials\| PubMed ID: 18533250	2008
Stop-flow lithography to generate cell-laden microgel particles. Lab on a chip\| PubMed ID: 18584079	2008
Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18599452	2008
Mechanically robust and bioadhesive collagen and photocrosslinkable hyaluronic acid semi-interpenetrating networks. Tissue engineering. Part A\| PubMed ID: 19105604	2009
Cell docking in double grooves in a microfluidic channel. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 19242937	2009
Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device. Lab on a chip\| PubMed ID: 19255657	2009
Electrochemical desorption of self-assembled monolayers for engineering cellular tissues. Biomaterials\| PubMed ID: 19362363	2009
Progress in tissue engineering. Scientific American\| PubMed ID: 19438051	2009
Integrating microfluidics and lensless imaging for point-of-care testing. Biosensors & bioelectronics\| PubMed ID: 19467854	2009
A hollow sphere soft lithography approach for long-term hanging drop methods. Tissue engineering. Part C, Methods\| PubMed ID: 19505251	2010
Micro- and nanoscale control of the cardiac stem cell niche for tissue fabrication. Tissue engineering. Part B, Reviews\| PubMed ID: 19552604	2009
Cell confinement in patterned nanoliter droplets in a microwell array by wiping. Journal of biomedical materials research. Part A\| PubMed ID: 19585570	2010
Layer by layer three-dimensional tissue epitaxy by cell-laden hydrogel droplets. Tissue engineering. Part C, Methods\| PubMed ID: 19586367	2010
Engineered 3D tissue models for cell-laden microfluidic channels. Analytical and bioanalytical chemistry\| PubMed ID: 19629459	2009
Future approaches to organ regeneration: microscale environments, stem cell engineering, and self-assembly of living tissues. Studies in health technology and informatics\| PubMed ID: 19745484	2009
Surface-directed assembly of cell-laden microgels. Biotechnology and bioengineering\| PubMed ID: 19777588	2010
Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19805103	2009
Arraycount, an algorithm for automatic cell counting in microwell arrays. BioTechniques\| PubMed ID: 19852758	2009
Method of Bottom-Up Directed Assembly of Cell-Laden Microgels. Cellular and molecular bioengineering\| PubMed ID: 19953195	2008
Nano/Microfluidics for diagnosis of infectious diseases in developing countries. Advanced drug delivery reviews\| PubMed ID: 19954755	2010
Rapid Formation of Acrylated Microstructures by Microwave-Induced Thermal Crosslinking. Macromolecular rapid communications\| PubMed ID: 20011617	2009
Microscale electroporation: challenges and perspectives for clinical applications. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 20023735	2009
Integration column: microwell arrays for mammalian cell culture. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 20027371	2009
Convection-driven generation of long-range material gradients. Biomaterials\| PubMed ID: 20035990	2010
Bioinspired materials for controlling stem cell fate. Accounts of chemical research\| PubMed ID: 20043634	2010
Microporous cell-laden hydrogels for engineered tissue constructs. Biotechnology and bioengineering\| PubMed ID: 20091766	2010
Controlling the porosity and microarchitecture of hydrogels for tissue engineering. Tissue engineering. Part B, Reviews\| PubMed ID: 20121414	2010
Modular Tissue Engineering: Engineering Biological Tissues from the Bottom Up. Soft matter\| PubMed ID: 20179781	2009
Controlled-size embryoid body formation in concave microwell arrays. Biomaterials\| PubMed ID: 20206991	2010
Rapid generation of biologically relevant hydrogels containing long-range chemical gradients. Advanced functional materials\| PubMed ID: 20216924	2010
A computational and experimental study inside microfluidic systems: the role of shear stress and flow recirculation in cell docking. Biomedical microdevices\| PubMed ID: 20300857	2010
Interface-directed self-assembly of cell-laden microgels. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 20358531	2010
Stochastic model of self-assembly of cell-laden hydrogels. Physical review. E, Statistical, nonlinear, and soft matter physics\| PubMed ID: 20365184	2009
Cell-laden microengineered gelatin methacrylate hydrogels. Biomaterials\| PubMed ID: 20417964	2010
Micro-masonry: construction of 3D structures by microscale self-assembly. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 20440697	2010
Preparation of arrays of cell spheroids and spheroid-monolayer cocultures within a microfluidic device. Journal of bioscience and bioengineering\| PubMed ID: 20591731	2010
Directed 3D cell alignment and elongation in microengineered hydrogels. Biomaterials\| PubMed ID: 20638973	2010
Cell-adhesive and mechanically tunable glucose-based biodegradable hydrogels. Acta biomaterialia\| PubMed ID: 20647064	2011
UV-assisted capillary force lithography for engineering biomimetic multiscale hierarchical structures: From lotus leaf to gecko foot hairs. Nanoscale\| PubMed ID: 20648269	2009
Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions. Biochimica et biophysica acta\| PubMed ID: 20655984	2011
Modified Gellan Gum hydrogels with tunable physical and mechanical properties. Biomaterials\| PubMed ID: 20663552	2010
Stimuli-responsive microwells for formation and retrieval of cell aggregates. Lab on a chip\| PubMed ID: 20664846	2010
Hybrid PGS-PCL microfibrous scaffolds with improved mechanical and biological properties. Journal of tissue engineering and regenerative medicine\| PubMed ID: 20669260	2011
Contributors to the emerging investigators issue. Lab on a chip\| PubMed ID: 20717627	2010
Microfluidic synthesis of composite cross-gradient materials for investigating cell-biomaterial interactions. Biotechnology and bioengineering\| PubMed ID: 20721897	2011
Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering. Biofabrication\| PubMed ID: 20823504	2010
Constrained watershed method to infer morphology of mammalian cells in microscopic images. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 20872884	2010
Hydrogels in regenerative medicine. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 20882499	2009
Patterned differentiation of individual embryoid bodies in spatially organized 3D hybrid microgels. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 20941801	2010
A sandwiched microarray platform for benchtop cell-based high throughput screening. Biomaterials\| PubMed ID: 20965560	2011
Methods for embryoid body formation: the microwell approach. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21042991	2011
Benchtop fabrication of PDMS microstructures by an unconventional photolithographic method. Biofabrication\| PubMed ID: 21076185	2010
Preventing cardiac remodeling: the combination of cell-based therapy and cardiac support therapy preserves left ventricular function in rodent model of myocardial ischemia. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 21078426	2010
Fabrication and characterization of tough elastomeric fibrous scaffolds for tissue engineering applications. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 21096824	2010
Fabrication of porous chitosan scaffolds for soft tissue engineering using dense gas CO2. Acta biomaterialia\| PubMed ID: 21130905	2011
Directed assembly of cell-laden hydrogels for engineering functional tissues. Organogenesis\| PubMed ID: 21220962	2010
Controlling the porosity of fibrous scaffolds by modulating the fiber diameter and packing density. Journal of biomedical materials research. Part A\| PubMed ID: 21225711	2011
Gradient biomaterials for soft-to-hard interface tissue engineering. Acta biomaterialia\| PubMed ID: 21232635	2011
Controlling the porosity of fibrous scaffolds by modulating the fiber diameter and packing density. Journal of biomedical materials research. Part A\| PubMed ID: 21254388	2011
Synthesis and characterization of photocrosslinkable gelatin and silk fibroin interpenetrating polymer network hydrogels. Acta biomaterialia\| PubMed ID: 21295165	2011
Deep wells integrated with microfluidic valves for stable docking and storage of cells. Biotechnology journal\| PubMed ID: 21298801	2011
Synthesis and characterization of tunable poly(ethylene glycol): gelatin methacrylate composite hydrogels. Tissue engineering. Part A\| PubMed ID: 21306293	2011
Directed assembly of cell-laden microgels for building porous three-dimensional tissue constructs. Journal of biomedical materials research. Part A\| PubMed ID: 21319297	2011
Sequential assembly of cell-laden hydrogel constructs to engineer vascular-like microchannels. Biotechnology and bioengineering\| PubMed ID: 21337336	2011
Microengineering hydrogels for stem cell bioengineering and tissue regeneration. JALA (Charlottesville, Va.)\| PubMed ID: 21344063	2010
Generating nonlinear concentration gradients in microfluidic devices for cell studies. Analytical chemistry\| PubMed ID: 21344866	2011
Surface-tension-driven gradient generation in a fluid stripe for bench-top and microwell applications. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21374805	2011
Cell-laden microengineered pullulan methacrylate hydrogels promote cell proliferation and 3D cluster formation. Soft matter\| PubMed ID: 21415929	2011
Responsive microgrooves for the formation of harvestable tissue constructs. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 21449596	2011
Nanoscale tissue engineering: spatial control over cell-materials interactions. Nanotechnology\| PubMed ID: 21451238	2011
Drug-eluting microarrays for cell-based screening of chemical-induced apoptosis. Analytical chemistry\| PubMed ID: 21476591	2011
A cell-based biosensor for real-time detection of cardiotoxicity using lensfree imaging. Lab on a chip\| PubMed ID: 21483937	2011
Surface functionalization of hyaluronic acid hydrogels by polyelectrolyte multilayer films. Biomaterials\| PubMed ID: 21571364	2011
Microfabricated polyester conical microwells for cell culture applications. Lab on a chip\| PubMed ID: 21614380	2011
Microscale technologies and modular approaches for tissue engineering: moving toward the fabrication of complex functional structures. ACS nano\| PubMed ID: 21627163	2011
Creation of bony microenvironment with CaP and cell-derived ECM to enhance human bone-marrow MSC behavior and delivery of BMP-2. Biomaterials\| PubMed ID: 21632105	2011
Anisotropic material synthesis by capillary flow in a fluid stripe. Biomaterials\| PubMed ID: 21684595	2011
Controlling the fibroblastic differentiation of mesenchymal stem cells via the combination of fibrous scaffolds and connective tissue growth factor. Tissue engineering. Part A\| PubMed ID: 21689062	2011
EMT-inducing biomaterials for heart valve engineering: taking cues from developmental biology. Journal of cardiovascular translational research\| PubMed ID: 21751069	2011
Responsive micromolds for sequential patterning of hydrogel microstructures. Journal of the American Chemical Society\| PubMed ID: 21766872	2011
Research highlights. Cell beads for building macroscopic tissues. Lab on a chip\| PubMed ID: 21773643	2011
Boston research takes center stage. Interview by Pamela Reynolds. IEEE pulse\| PubMed ID: 21791397	2011
Preface to Special Topic: Microfluidics in cell biology and tissue engineering. Biomicrofluidics\| PubMed ID: 21799707	2011
A microfluidic-based neurotoxin concentration gradient for the generation of an in vitro model of Parkinson's disease. Biomicrofluidics\| PubMed ID: 21799720	2011
SAM-based cell transfer to photopatterned hydrogels for microengineering vascular-like structures. Biomaterials\| PubMed ID: 21802723	2011
二维组合稀释集成微流控设备。 Lab on a chip\| PubMed ID: 21837312	2011
Engineering of pathways, cells and tissues. Current opinion in biotechnology\| PubMed ID: 21862311	2011
BIOMIMETIC GRADIENT HYDROGELS FOR TISSUE ENGINEERING. The Canadian journal of chemical engineering\| PubMed ID: 21874065	2010
Digitally tunable physicochemical coding of material composition and topography in continuous microfibres. Nature materials\| PubMed ID: 21892177	2011
Enhancing cell penetration and proliferation in chitosan hydrogels for tissue engineering applications. Biomaterials\| PubMed ID: 21925727	2011
Application of microtechnologies for the vascularization of engineered tissues. Vascular cell\| PubMed ID: 22040627	2011
Biomimetic tissues on a chip for drug discovery. Drug discovery today\| PubMed ID: 22094245	2012
Engineering Approaches Toward Deconstructing and Controlling the Stem Cell Environment. Annals of biomedical engineering\| PubMed ID: 22101755	2011
Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering. Lab on a chip\| PubMed ID: 22105780	2012
Carbon nanotube reinforced hybrid microgels as scaffold materials for cell encapsulation. ACS nano\| PubMed ID: 22117858	2012
Hydrogels and microtechnologies for engineering the cellular microenvironment. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology\| PubMed ID: 22144036	2011
Designer Hydrophilic Regions Regulate Droplet Shape for Controlled Surface Patterning and 3D Microgel Synthesis. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 22162397	2012
Microfabrication technologies for oral drug delivery. Advanced drug delivery reviews\| PubMed ID: 22166590	2011
Multi-gradient hydrogels produced layer by layer with capillary flow and crosslinking in open microchannels. Lab on a chip\| PubMed ID: 22167009	2012
Controlled release of drugs from gradient hydrogels for high-throughput analysis of cell-drug interactions. Analytical chemistry\| PubMed ID: 22220576	2012
Hydrogel surfaces to promote attachment and spreading of endothelial progenitor cells. Journal of tissue engineering and regenerative medicine\| PubMed ID: 22223475	2012
Osteoblastic/Cementoblastic and Neural Differentiation of Dental Stem Cells and Their Applications to Tissue Engineering and Regenerative Medicine. Tissue engineering. Part B, Reviews\| PubMed ID: 22224548	2012
Research highlights. Lab on a chip\| PubMed ID: 22249860	2012
Delving into BioMEMS. IEEE pulse\| PubMed ID: 22250335	2011
The mechanical properties and cytotoxicity of cell-laden double-network hydrogels based on photocrosslinkable gelatin and gellan gum biomacromolecules. Biomaterials\| PubMed ID: 22265786	2012
Research highlights. Lab on a chip\| PubMed ID: 22298296	2012
Research highlights. Lab on a chip\| PubMed ID: 22334379	2012