Olaf Kutsch

Department of Medicine, University of Alabama at Birmingham

Affiliated withUniversity of Alabama at Birmingham

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2017

Other Publications

Article	Year
Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells. Molecular and cellular biology\| PubMed ID: 11784850	2002
Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency. Journal of virology\| PubMed ID: 12163598	2002
CD154-CD40-induced reactivation of latent HIV-1 infection. Virology\| PubMed ID: 14517079	2003
Dynamics of HIV-1 recombination in its natural target cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15010526	2004
Bis-anthracycline antibiotics inhibit human immunodeficiency virus type 1 transcription. Antimicrobial agents and chemotherapy\| PubMed ID: 15105117	2004
Tat inhibitors, a new approach: interview with Olaf Kutsch, Ph.D. Interview by John S. James. AIDS treatment news\| PubMed ID: 15791713	2005
T-cell line for HIV drug screening using EGFP as a quantitative marker of HIV-1 replication. BioTechniques\| PubMed ID: 16454046	2006
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell\| PubMed ID: 16777597	2006
A high-throughput drug screening system for HIV-1 transcription inhibitors. Journal of biomolecular screening\| PubMed ID: 16831859	2006
High throughput drug screening for human immunodeficiency virus type 1 reactivating compounds. Assay and drug development technologies\| PubMed ID: 17477827	2007
Optimization of HIV-1 infectivity assays. BioTechniques\| PubMed ID: 18072587	2007
The quality of chimpanzee T-cell activation and simian immunodeficiency virus/human immunodeficiency virus susceptibility achieved via antibody-mediated T-cell receptor/CD3 stimulation is a ... Journal of virology\| PubMed ID: 18667496	2008
Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma. Journal of virology\| PubMed ID: 19019969	2009
Determinants of the establishment of human immunodeficiency virus type 1 latency. Journal of virology\| PubMed ID: 19144703	2009
Effective activation alleviates the replication block of CCR5-tropic HIV-1 in chimpanzee CD4+ lymphocytes. Virology\| PubMed ID: 19748647	2009
Adjusting transgene expression levels in lymphocytes with a set of inducible promoters. The journal of gene medicine\| PubMed ID: 20527043	2010
Hit-and-run stimulation: a novel concept to reactivate latent HIV-1 infection without cytokine gene induction. Journal of virology\| PubMed ID: 20538859	2010
Suppressor of cytokine signaling 3 inhibits antiviral IFN-beta signaling to enhance HIV-1 replication in macrophages. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20631305	2010
A screen to identify small molecule inhibitors of protein-protein interactions in mycobacteria. Assay and drug development technologies\| PubMed ID: 21281130	2011
Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors. Virology\| PubMed ID: 21514616	2011
Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids. Chemistry & biology\| PubMed ID: 21944757	2011
Validating a firefly luciferase-based high-throughput screening assay for antimalarial drug discovery. Assay and drug development technologies\| PubMed ID: 22050430	2012
Facts and fiction: cellular models for high throughput screening for HIV-1 reactivating drugs. Current HIV research\| PubMed ID: 22211661	2011
Kinase control prevents HIV-1 reactivation in spite of high levels of induced NF-κB activity. Journal of virology\| PubMed ID: 22345467	2012
Selected drugs with reported secondary cell-differentiating capacity prime latent HIV-1 infection for reactivation. Journal of virology\| PubMed ID: 22696646	2012
Host factor transcriptional regulation contributes to preferential expression of HIV type 1 in IL-4-producing CD4 T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22875803	2012
Effective non-viral delivery of siRNA to acute myeloid leukemia cells with lipid-substituted polyethylenimines. PloS one\| PubMed ID: 22952927	2012
An AP-1 binding site in the enhancer/core element of the HIV-1 promoter controls the ability of HIV-1 to establish latent infection. Journal of virology\| PubMed ID: 23236059	2013
Copper-boosting compounds: a novel concept for antimycobacterial drug discovery. Antimicrobial agents and chemotherapy\| PubMed ID: 23254420	2013
Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivation. Journal of virology\| PubMed ID: 24155393	2014
Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy\| PubMed ID: 24752262	2014
Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection. Journal of virology\| PubMed ID: 25878110	2015
Disulfiram and Copper Ions Kill Mycobacterium tuberculosis in a Synergistic Manner. Antimicrobial agents and chemotherapy\| PubMed ID: 26033731	2015
The host cell side of latent HIV-1 infection. Oncotarget\| PubMed ID: 26343367	2015
RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promoters. Virology\| PubMed ID: 26379089	2015
Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 26742943	2016
Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-staphylococcal activity. Metallomics : integrated biometal science\| PubMed ID: 26935206	2016
Protein Phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection. Oncotarget\| PubMed ID: 27004401	2016
A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis. Assay and drug development technologies\| PubMed ID: 27327048	2016
8-Hydroxyquinolines Are Boosting Agents of Copper-Related Toxicity in Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy\| PubMed ID: 27431227	2016
Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis. Scientific reports\| PubMed ID: 28176854	2017