Department of Anatomy and Embryology
Christine L. Mummery has not added Biography.
If you are Christine L. Mummery and would like to personalize this page please email our Author Liaison for assistance.
SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development.
Developmental dynamics : an official publication of the American Association of Anatomists Feb, 2007 | Pubmed ID: 17195180
Prospects for pluripotent stem cell-derived cardiomyocytes in cardiac cell therapy and as disease models.
Journal of cellular biochemistry Jul, 2009 | Pubmed ID: 19449339
Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes.
Cellular and molecular life sciences : CMLS Jan, 2010 | Pubmed ID: 19844658
Challenges in using stem cells for cardiac repair.
Science translational medicine Apr, 2010 | Pubmed ID: 20393186
Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models.
The Biochemical journal Feb, 2011 | Pubmed ID: 21269276
Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development.
Trends in molecular medicine Sep, 2011 | Pubmed ID: 21703926
Shedding new light on the mechanism underlying stem cell therapy for the heart.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2011 | Pubmed ID: 21720378
Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterparts.
PloS one , 2011 | Pubmed ID: 21931658
New perspectives on regeneration of the heart.
Circulation research Sep, 2011 | Pubmed ID: 21960722
Smooth muscle diversity from human pluripotent cells.
Nature biotechnology Feb, 2012 | Pubmed ID: 22318032
Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease.
Circulation Jun, 2012 | Pubmed ID: 22647976
Induced pluripotent stem cells: the new patient?
Nature reviews. Molecular cell biology Nov, 2012 | Pubmed ID: 23034453
Model systems for cardiovascular regenerative biology.
Cold Spring Harbor perspectives in medicine Apr, 2013 | Pubmed ID: 23545574
Is heart regeneration on the right track?
Nature medicine Apr, 2013 | Pubmed ID: 23558629
Conversion of mature human β-cells into glucagon-producing α-cells.
Diabetes Jul, 2013 | Pubmed ID: 23569174
Generation of induced pluripotent stem cells from human foetal fibroblasts using the Sleeping Beauty transposon gene delivery system.
Differentiation; research in biological diversity Jul-Sep, 2013 | Pubmed ID: 23933400
Direct cardiomyocyte reprogramming: a new direction for cardiovascular regenerative medicine.
Cold Spring Harbor perspectives in medicine Sep, 2013 | Pubmed ID: 24003244
Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2014 | Pubmed ID: 24158517
Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome.
The EMBO journal Dec, 2013 | Pubmed ID: 24213244
PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function.
Stem cell reports , 2013 | Pubmed ID: 24371810
Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones.
Experimental cell research Oct, 2014 | Pubmed ID: 24836851
Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells.
Nature protocols , 2014 | Pubmed ID: 24874816
SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development.
Stem cell research Jul, 2014 | Pubmed ID: 24968096
Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes.
Journal of cellular and molecular medicine Aug, 2014 | Pubmed ID: 24981391
Cell replacement therapies: is it time to reprogram?
Human gene therapy Oct, 2014 | Pubmed ID: 25141889
Assessment of functional competence of endothelial cells from human pluripotent stem cells in zebrafish embryos.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 25173378
A case for crowd sourcing in stem cell research.
Stem cells translational medicine Nov, 2014 | Pubmed ID: 25232185
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2014 | Pubmed ID: 25453094
Pluripotent stem cell derived cardiovascular progenitors--a developmental perspective.
Developmental biology Apr, 2015 | Pubmed ID: 25624264
Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes Under Defined Conditions.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 25626427
Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.
EMBO molecular medicine Apr, 2015 | Pubmed ID: 25700171
Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro--correlation between contraction force and electrophysiology.
Biomaterials May, 2015 | Pubmed ID: 25771005
Lymphangiogenesis and angiogenesis during human fetal pancreas development.
Vascular cell , 2014 | Pubmed ID: 25785186
Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2015 | Pubmed ID: 25795241
What Endothelial Cells from Patient iPSCs Can Tell Us about Aortic Valve Disease.
Cell stem cell May, 2015 | Pubmed ID: 25957898
The composition and differentiation potential of the duodenal intraepithelial innate lymphocyte compartment is altered in coeliac disease.
Gut Aug, 2016 | Pubmed ID: 25966995
KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas.
Stem cell reports Jun, 2015 | Pubmed ID: 26028532
Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells.
Nature biotechnology Sep, 2015 | Pubmed ID: 26192318
Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells.
Development (Cambridge, England) Sep, 2015 | Pubmed ID: 26209647
Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure.
Biochemical and biophysical research communications Nov, 2015 | Pubmed ID: 26456652
Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function.
Cell reports Oct, 2015 | Pubmed ID: 26489474
Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva.
Stem cell reports Dec, 2015 | Pubmed ID: 26626181
Advantages of the avian model for human ovarian cancer.
Molecular and clinical oncology Nov, 2015 | Pubmed ID: 26807219
Interaction Between ALK1 Signaling and Connexin40 in the Development of Arteriovenous Malformations.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2016 | Pubmed ID: 26821948
The avian embryo to study development of the cardiac conduction system.
Differentiation; research in biological diversity Apr-Jun, 2016 | Pubmed ID: 26856662
Complex Tissue and Disease Modeling using hiPSCs.
Cell stem cell Mar, 2016 | Pubmed ID: 26942851
Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure.
European heart journal Apr, 2016 | Pubmed ID: 27055812
Stem cells: The cancer's gone, but did chemotherapy damage your heart?
Nature reviews. Cardiology Jul, 2016 | Pubmed ID: 27226155
Concise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease.
Stem cells (Dayton, Ohio) Aug, 2016 | Pubmed ID: 27250776
Inherited heart disease - what can we expect from the second decade of human iPS cell research?
FEBS letters Aug, 2016 | Pubmed ID: 27391414
A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells.
EMBO molecular medicine 09, 2016 | Pubmed ID: 27470144
Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?
British journal of pharmacology Sep, 2016 | Pubmed ID: 27641943
Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying Nonsense Mutations in the Sodium Channel Gene SCN5A.
Circulation. Arrhythmia and electrophysiology Nov, 2016 | Pubmed ID: 27784737
Small molecule absorption by PDMS in the context of drug response bioassays.
Biochemical and biophysical research communications Jan, 2017 | Pubmed ID: 27856254
TECRL, a new life-threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT.
EMBO molecular medicine 12, 2016 | Pubmed ID: 27861123
Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes.
Biochemical and biophysical research communications 03, 2018 | Pubmed ID: 28153730
Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes.
European heart journal Jan, 2017 | Pubmed ID: 28182242
Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells.
Development (Cambridge, England) Mar, 2017 | Pubmed ID: 28279973
Differentiation-Defective Human Induced Pluripotent Stem Cells Reveal Strengths and Limitations of the Teratoma Assay and In Vitro Pluripotency Assays.
Stem cell reports 05, 2017 | Pubmed ID: 28494940
FANTOM5 CAGE profiles of human and mouse samples.
Scientific data 08, 2017 | Pubmed ID: 28850106
Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies.
Disease models & mechanisms 09, 2017 | Pubmed ID: 28883014
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells.
Nature communications 10, 2017 | Pubmed ID: 29030611
Co-Differentiation of Human Pluripotent Stem Cells-Derived Cardiomyocytes and Endothelial Cells from Cardiac Mesoderm Provides a Three-Dimensional Model of Cardiac Microtissue.
Current protocols in human genetics 10, 2017 | Pubmed ID: 29044469
Executive summary of the 12th HHT international scientific conference.
Angiogenesis Feb, 2018 | Pubmed ID: 29147802
A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes.
Stem cell reports 12, 2017 | Pubmed ID: 29173897
Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells.
Stem cell reports 12, 2017 | Pubmed ID: 29173898
MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.
Circulation research Feb, 2018 | Pubmed ID: 29282212
Squaramide-Based Supramolecular Materials for Three-Dimensional Cell Culture of Human Induced Pluripotent Stem Cells and Their Derivatives.
Biomacromolecules Apr, 2018 | Pubmed ID: 29528623
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.
Nature communications 04, 2018 | Pubmed ID: 29636455
Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells.
Stem cell reports May, 2018 | Pubmed ID: 29657098
Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology.
Advanced drug delivery reviews Jun, 2018 | Pubmed ID: 29944904
Quantification of Muscle Contraction In Vitro and In Vivo Using MUSCLEMOTION Software: From Stem Cell-Derived Cardiomyocytes to Zebrafish and Human Hearts.
Current protocols in human genetics Oct, 2018 | Pubmed ID: 30253059
Cytostretch, an Organ-on-Chip Platform.
Micromachines Jul, 2016 | Pubmed ID: 30404293
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved