Beat Lutz

Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz

Affiliated withUniversity Medical Center of the Johannes Gutenberg University Mainz

Research Area

Neuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2022

Other Publications

Article	Year
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20445053	2010
Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21289174	2011
Circuit specific functions of cannabinoid CB1 receptor in the balance of investigatory drive and exploration. PloS one\| PubMed ID: 22069458	2011
A polymorphism in the gene of the endocannabinoid-degrading enzyme FAAH (FAAH C385A) is associated with emotional-motivational reactivity. Psychopharmacology\| PubMed ID: 22776995	2012
Identification and quantification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors. The Journal of biological chemistry\| PubMed ID: 22952224	2012
Neuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampus. Journal of neurochemistry\| PubMed ID: 23289830	2013
Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23785142	2013
Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24167249	2013
A restricted population of CB1 cannabinoid receptors with neuroprotective activity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24843137	2014
Oligodendrocyte precursor cells modulate the neuronal network by activity-dependent ectodomain cleavage of glial NG2. PLoS biology\| PubMed ID: 25387269	2014
Impaired border zone formation and adverse remodeling after reperfused myocardial infarction in cannabinoid CB2 receptor deficient mice. Life sciences\| PubMed ID: 25447445	2015
Anxiety, Stress, and Fear Response in Mice With Reduced Endocannabinoid Levels. Biological psychiatry\| PubMed ID: 25981172	2016
Age-related changes in the endocannabinoid system in the mouse hippocampus. Mechanisms of ageing and development\| PubMed ID: 26278494	2015
Cannabinoid type-1 receptor signaling in central serotonergic neurons regulates anxiety-like behavior and sociability. Frontiers in behavioral neuroscience\| PubMed ID: 26388750	2015
A runner's high depends on cannabinoid receptors in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26438875	2015
Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB1 receptors on developing cortical neurons. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26460022	2015
Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26468198	2015
The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons. PLoS biology\| PubMed ID: 26496209	2015
Evaluation of MRI and cannabinoid type 1 receptor PET templates constructed using DARTEL for spatial normalization of rat brains. Medical physics\| PubMed ID: 26632044	2015
Lack of hippocampal CB1 receptor desensitization by Δ(9)-tetrahydrocannabinol in aged mice and by low doses of JZL 184. Naunyn-Schmiedeberg's archives of pharmacology\| PubMed ID: 26984820	2016
Extraction and Simultaneous Quantification of Endocannabinoids and Endocannabinoid-Like Lipids in Biological Tissues. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27245887	2016
Anatomical characterization of the cannabinoid CB receptor in cell-type-specific mutant mouse rescue models. The Journal of comparative neurology\| PubMed ID: 27339436	2017
Peripheral and central CB1 cannabinoid receptors control stress-induced impairment of memory consolidation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27528659	2016
Cell Type-Specific Tandem Affinity Purification of the Mouse Hippocampal CB1 Receptor-Associated Proteome. Journal of proteome research\| PubMed ID: 27596989	2016
Restricted vs. unrestricted wheel running in mice: Effects on brain, behavior and endocannabinoids. Hormones and behavior\| PubMed ID: 27664019	2016
Adverse Social Experiences in Adolescent Rats Result in Enduring Effects on Social Competence, Pain Sensitivity and Endocannabinoid Signaling. Frontiers in behavioral neuroscience\| PubMed ID: 27812328	2016
Targeting brain and peripheral plasticity of the lipidome in acute kainic acid-induced epileptic seizures in mice via quantitative mass spectrometry. Biochimica et biophysica acta. Molecular and cell biology of lipids\| PubMed ID: 27871881	2017
Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 28102227	2017
Addressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons. Brain structure & function\| PubMed ID: 28393261	2017
Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016. Molecular and cellular pediatrics\| PubMed ID: 28516419	2017
Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28584105	2017
Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse. Journal of neurochemistry\| PubMed ID: 28608535	2017
Pharmacokinetics of the cannabinoid receptor ligand [ F]MK-9470 in the rat brain - Evaluation of models using microPET. Medical physics\| PubMed ID: 29244904	2018
Age-related regulation of bone formation by the sympathetic cannabinoid CB1 receptor. Bone\| PubMed ID: 29274505	2018
Localization of the cannabinoid type-1 receptor in subcellular astrocyte compartments of mutant mouse hippocampus. Glia\| PubMed ID: 29480581	2018
Elevated levels of 2-arachidonoylglycerol promote atherogenesis in ApoE-/- mice. PloS one\| PubMed ID: 29813086	2018
Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis. Nature neuroscience\| PubMed ID: 30258239	2018
Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampus. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 30307491	2018
Publisher Correction: Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis. Nature neuroscience\| PubMed ID: 30405214	2019
Prophylactic Palmitoylethanolamide Prolongs Survival and Decreases Detrimental Inflammation in Aged Mice With Bacterial Meningitis. Frontiers in immunology\| PubMed ID: 30505308	2018
Impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 30532004	2019
Multiple endocannabinoid-mediated mechanisms in the regulation of energy homeostasis in brain and peripheral tissues. Cellular and molecular life sciences : CMLS\| PubMed ID: 30599065	2019
Gadd45α modulates aversive learning through post-transcriptional regulation of memory-related mRNAs. EMBO reports\| PubMed ID: 30948457	2019
Cell type specific impact of cannabinoid receptor signaling in somatosensory barrel map formation in mice. The Journal of comparative neurology\| PubMed ID: 31226222	2020
Broad Lipidomic and Transcriptional Changes of Prophylactic PEA Administration in Adult Mice. Frontiers in neuroscience\| PubMed ID: 31244590	2019
Adipocyte cannabinoid CB1 receptor deficiency alleviates high fat diet-induced memory deficit, depressive-like behavior, neuroinflammation and impairment in adult neurogenesis. Psychoneuroendocrinology\| PubMed ID: 31491589	2019
Endocannabinoid 2-arachidonoylglycerol is elevated in the coronary circulation during acute coronary syndrome. PloS one\| PubMed ID: 31887202	2019
Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 31982904	2020
A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction. Nature communications\| PubMed ID: 32034128	2020
The endocannabinoid 2-arachidonoylglycerol inhibits endothelial function and repair. International journal of cardiology\| PubMed ID: 32810540	2021
Differential glutamatergic and GABAergic contributions to the tetrad effects of Δ-tetrahydrocannabinol revealed by cell-type-specific reconstitution of the CB1 receptor. Neuropharmacology\| PubMed ID: 32860777	2020
Cell type-specific genetic reconstitution of CB1 receptor subsets to assess their role in exploratory behaviour, sociability, and memory. The European journal of neuroscience\| PubMed ID: 33253450	2022
Quantification of the Cannabinoid Type 1 Receptor Availability in the Mouse Brain. Frontiers in neuroanatomy\| PubMed ID: 33328905	2020
Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons drives overconsumption of palatable food and obesity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 33558679	2021
Exercise-induced euphoria and anxiolysis do not depend on endogenous opioids in humans. Psychoneuroendocrinology\| PubMed ID: 33582575	2021
Chronic social stress lessens the metabolic effects induced by a high-fat diet. The Journal of endocrinology\| PubMed ID: 33608492	2021
Transcriptional signatures in prefrontal cortex confer vulnerability versus resilience to food and cocaine addiction-like behavior. Scientific reports\| PubMed ID: 33907201	2021
Cannabis Use and Car Crashes: A Review. Frontiers in psychiatry\| PubMed ID: 34122176	2021
Stress-Related Dysfunction of Adult Hippocampal Neurogenesis-An Attempt for Understanding Resilience? International journal of molecular sciences\| PubMed ID: 34298958	2021
Subsynaptic Distribution, Lipid Raft Targeting and G Protein-Dependent Signalling of the Type 1 Cannabinoid Receptor in Synaptosomes from the Mouse Hippocampus and Frontal Cortex. Molecules (Basel, Switzerland)\| PubMed ID: 34833992	2021
Association of Innate and Acquired Aerobic Capacity With Resilience in Healthy Adults: Protocol for a Randomized Controlled Trial of an 8-Week Web-Based Physical Exercise Intervention. JMIR research protocols\| PubMed ID: 34847062	2021