Department of Biomedical Engineering,
Institute for Complex Molecular Systems (ICMS),
Institute for Complex Molecular Systems
Dr. Nicholas Kurniawan is an Assistant Professor at the Department of Biomedical Engineering in Eindhoven University of Technology, the Netherlands. His research focuses on understanding how the physical and mechanical interactions between cells and cellular environments shape physiological tissue function and drive pathologies. His interdisciplinary team combines approaches from biophysics, mechanobiology, microfabrication, and cell biology with an outlook of exploiting cell–materials interactions for regenerative medicine applications.
Mechanobiology of cell migration in the context of dynamic two-way cell-matrix interactions.
Journal of biomechanics 05, 2016 | Pubmed ID: 26747513
Fibrin-fiber architecture influences cell spreading and differentiation.
Cell adhesion & migration 09, 2016 | Pubmed ID: 26910190
Fibrin Networks Support Recurring Mechanical Loads by Adapting their Structure across Multiple Scales.
Biophysical journal Sep, 2016 | Pubmed ID: 27602730
Porosity Governs Normal Stresses in Polymer Gels.
Physical review letters Nov, 2016 | Pubmed ID: 27911537
Buffers Strongly Modulate Fibrin Self-Assembly into Fibrous Networks.
Langmuir : the ACS journal of surfaces and colloids 06, 2017 | Pubmed ID: 28558246
Vascular Mechanobiology: Towards Control of In Situ Regeneration.
Cells Jul, 2017 | Pubmed ID: 28671618
An automated quantitative analysis of cell, nucleus and focal adhesion morphology.
PloS one , 2018 | Pubmed ID: 29601604
Decoupling the Effect of Shear Stress and Stretch on Tissue Growth and Remodeling in a Vascular Graft.
Tissue engineering. Part C, Methods 07, 2018 | Pubmed ID: 29877143
Mesoscale substrate curvature overrules nanoscale contact guidance to direct bone marrow stromal cell migration.
Journal of the Royal Society, Interface 08, 2018 | Pubmed ID: 30089684
A stirring system using suspended magnetically-actuated pillars for controlled cell clustering.
Soft matter Feb, 2019 | Pubmed ID: 30666323
Image-based analysis of uniaxial ring test for mechanical characterization of soft materials and biological tissues.
Soft matter Apr, 2019 | Pubmed ID: 30924833
Entropic Forces Drive Cellular Contact Guidance.
Biophysical journal 05, 2019 | Pubmed ID: 31053262
The ins and outs of engineering functional tissues and organs: evaluating the in-vitro and in-situ processes.
Current opinion in organ transplantation 10, 2019 | Pubmed ID: 31389812
Hemodynamic loads distinctively impact the secretory profile of biomaterial-activated macrophages - implications for in situ vascular tissue engineering.
Biomaterials science Dec, 2019 | Pubmed ID: 31709425
Cellular Geometry Sensing at Different Length Scales and its Implications for Scaffold Design.
Materials (Basel, Switzerland) Feb, 2020 | Pubmed ID: 32098110
Human In Vitro Model Mimicking Material-Driven Vascular Regeneration Reveals How Cyclic Stretch and Shear Stress Differentially Modulate Inflammation and Matrix Deposition.
Advanced biosystems 06, 2020 | Pubmed ID: 32390338
Cell-Perceived Substrate Curvature Dynamically Coordinates the Direction, Speed, and Persistence of Stromal Cell Migration.
Advanced biosystems 10, 2019 | Pubmed ID: 32648723
Cellular Contact Guidance Emerges from Gap Avoidance.
Cell reports. Physical science May, 2020 | Pubmed ID: 32685934
Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling.
Soft matter Sep, 2020 | Pubmed ID: 32935715
Mechanical and Physical Regulation of Fibroblast-Myofibroblast Transition: From Cellular Mechanoresponse to Tissue Pathology.
Frontiers in bioengineering and biotechnology , 2020 | Pubmed ID: 33425874
Methods to Model Cardiac Mechanobiology in Health and Disease.
Tissue engineering. Part C, Methods 03, 2021 | Pubmed ID: 33514281
Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue.
Communications biology 05, 2021 | Pubmed ID: 33972658
Protein Micropatterning in 2.5D: An Approach to Investigate Cellular Responses in Multi-Cue Environments.
ACS applied materials & interfaces Jun, 2021 | Pubmed ID: 34032413
Mechanical Properties of Bioengineered Corneal Stroma.
Advanced healthcare materials 10, 2021 | Pubmed ID: 34369098
In-vitro engineered human cerebral tissues mimic pathological circuit disturbances in 3D.
Communications biology 03, 2022 | Pubmed ID: 35322168
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