Christopher C. W. Hughes

Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression.

VEGF(121) and VEGF(165) regulate blood vessel diameter through vascular endothelial growth factor receptor 2 in an in vitro angiogenesis model.

Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis.

HESR1/CHF2 suppresses VEGFR2 transcription independent of binding to E-boxes.

Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration.

Mesenchymal stem cells enhance angiogenesis in mechanically viable prevascularized tissues via early matrix metalloproteinase upregulation.

Endothelial-stromal interactions in angiogenesis.

An optimized three-dimensional in vitro model for the analysis of angiogenesis.

Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature.

TNF induction of jagged-1 in endothelial cells is NFkappaB-dependent.

Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2.

BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: implications for hereditary hemorrhagic telangiectasia type II.

Macrophages and angiogenesis: a role for Wnt signaling.

Analysis of stromal cell secretomes reveals a critical role for stromal cell-derived hepatocyte growth factor and fibronectin in angiogenesis.

Angiogenic sprouting is regulated by endothelial cell expression of Slug.

Interferon-induced transmembrane protein 1 regulates endothelial lumen formation during angiogenesis.

A role for partial endothelial-mesenchymal transitions in angiogenesis?

Executive summary of the 11th HHT international scientific conference.

Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels.

mTORC2 mediates CXCL12-induced angiogenesis.

Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth.

A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications.

3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels.

Executive summary of the 12th HHT international scientific conference.

Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia.

Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions.

Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis.

An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy.

The vascular niche in next generation microphysiological systems.

Correction: The vascular niche in next generation microphysiological systems.

Adoptive T-Cell Therapy in Advanced Colorectal Cancer: A Systematic Review.

Organotypic stromal cells impact endothelial cell transcriptome in 3D microvessel networks.

A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease.