Yen-Lin Chen

Yen-Lin Chen

Robert M. Berne Cardiovascular Research Center, University of Virginia

Affiliated withUniversity of Virginia

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Endothelial TRPV4 channels and vasodilator reactivity. Current topics in membranes\| PubMed ID: 32402646	2020
Mechanisms underlying selective coupling of endothelial Ca signals with eNOS vs. IK/SK channels in systemic and pulmonary arteries. The Journal of physiology\| PubMed ID: 32463112	2020
A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability. Science signaling\| PubMed ID: 33653920	2021
Calcium Signal Profiles in Vascular Endothelium from Cdh5-GCaMP8 and Cx40-GCaMP2 Mice. Journal of vascular research\| PubMed ID: 33706307	2021
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 33853948	2021
Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 33879616	2021
Endothelial pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure in mice. eLife\| PubMed ID: 34490843	2021
Mechanosensitive Angiotensin II Receptor Signaling in Pressure-Induced Vasoconstriction. Journal of the American Heart Association\| PubMed ID: 35156384	2022
Definitive high-dose, proton-based radiation for unresected mobile spine and sacral chordomas. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology\| PubMed ID: 35429502	2022
Novel Smooth Muscle Ca-Signaling Nanodomains in Blood Pressure Regulation. Circulation\| PubMed ID: 35758040	2022
Endothelial IK and SK channel activation decreases pulmonary arterial pressure and vascular remodeling in pulmonary hypertension. Pulmonary circulation\| PubMed ID: 36686408	2023
Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1. JCI insight\| PubMed ID: 37014698	2023
Purinergic P2Y2 Receptor-Induced Activation of Endothelial TRPV4 Channels Mediates Lung Ischemia-Reperfusion Injury. bioRxiv : the preprint server for biology\| PubMed ID: 37397979	2023
The Polyanionic Drug Suramin Neutralizes Histones and Prevents Endotheliopathy. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 37405700	2023
Purinergic P2Y2 receptor-induced activation of endothelial TRPV4 channels mediates lung ischemia-reperfusion injury. Science signaling\| PubMed ID: 37874885	2023
Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress. Science signaling\| PubMed ID: 38289985	2024
Editorial: Calcium regulation and Mechano-transduction in vascular diseases: obligatory role of transient receptor potential and Piezo channels. Frontiers in physiology\| PubMed ID: 38482192	2024