Sarah Q. Crome

Soham and Shaila Ajmera Family Transplant Centre, University Health Network

Affiliated withUniversity Health Network University of Toronto

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Adenoviral-transduced dendritic cells are susceptible to suppression by T regulatory cells and promote interleukin 17 production. Cancer immunology, immunotherapy : CII\| PubMed ID: 21153637	2011
Natural killer cells regulate diverse T cell responses. Trends in immunology\| PubMed ID: 23601842	2013
A distinct innate lymphoid cell population regulates tumor-associated T cells. Nature medicine\| PubMed ID: 28165478	2017
Immunoregulatory functions of innate lymphoid cells. Journal for immunotherapy of cancer\| PubMed ID: 30454038	2018
Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer. Oncoimmunology\| PubMed ID: 31741762	2019
High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation. Journal for immunotherapy of cancer\| PubMed ID: 31892360	2019
NK Cells Regulate CD8 T Cell Mediated Autoimmunity. Frontiers in cellular and infection microbiology\| PubMed ID: 32117809	2020
Interactions between islets and regulatory immune cells in health and type 1 diabetes. Diabetologia\| PubMed ID: 34550422	2021
Searching for the Elusive Regulatory Innate Lymphoid Cell. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 34607908	2021
Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human disease. Science translational medicine\| PubMed ID: 34669443	2021
Immune Checkpoints and Innate Lymphoid Cells-New Avenues for Cancer Immunotherapy. Cancers\| PubMed ID: 34885076	2021
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles. Science immunology\| PubMed ID: 34995099	2022
Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses. JCI insight\| PubMed ID: 35133979	2022
Tissue-Dependent Adaptations and Functions of Innate Lymphoid Cells. Frontiers in immunology\| PubMed ID: 35359972	2022
Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity. Nature communications\| PubMed ID: 36496458	2022
Strategies for optimizing CITE-seq for human islets and other tissues. Frontiers in immunology\| PubMed ID: 36936943	2023
Protective and pathogenic functions of innate lymphoid cells in transplantation. Clinical and experimental immunology\| PubMed ID: 37119279	2023
Efficient and stable CRISPR/Cas9-mediated genome-editing of human type 2 innate lymphoid cells. Frontiers in immunology\| PubMed ID: 37868976	2023
Generation of an Inhibitory NK Cell Subset by TGF-β1/IL-15 Polarization. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 38668728	2024
Enhanced Type 1 Interferon Signature in Axial Spondyloarthritis Patients Unresponsive to Secukinumab Treatment. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 39160761	2025
Single cell profiling of hematopoietic stem cell transplant recipients reveals TGF-β1 and IL-2 confer immunoregulatory functions to NK cells. iScience\| PubMed ID: 39720529	2024
Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses. Cell reports\| PubMed ID: 39721022	2025
Single-cell RNA sequencing of circulating immune cells supports inhibition of and translation as psoriatic arthritis biomarkers. Frontiers in immunology\| PubMed ID: 39991156	2025
CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor Microenvironment. Cancer immunology research\| PubMed ID: 40084939	2025
The art of war: burning stores to fuel anti-viral immunity. Nature metabolism\| PubMed ID: 40217116	2025
Endothelial dysfunction drives atherosclerotic plaque macrophage-dependent abdominal aortic aneurysm formation. Nature immunology\| PubMed ID: 40263614	2025
Cell therapy with human IL-10-producing ILC2s enhances islet function and inhibits allograft rejection. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 40412656	2025