Somaira Nowsheen

Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.

Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice.

DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation.

Tumors induce complex DNA damage in distant proliferative tissues in vivo.

Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons.

Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma.

The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy.

p53-dependent BRCA1 nuclear export controls cellular susceptibility to DNA damage.

Cetuximab augments cytotoxicity with poly (adp-ribose) polymerase inhibition in head and neck cancer.

Molecular markers for cancer prognosis and treatment: have we struck gold?

Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors.

Kinomic profiling approach identifies Trk as a novel radiation modulator.

MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma.

Epigenetic inactivation of DNA repair in breast cancer.

Targeting BRCA1 Localization to Augment Breast Tumor Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition.

HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair.

Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells.

Endoglin (CD105) Contributes to Platinum Resistance and Is A Target for Tumor-Specific Therapy in Epithelial Ovarian Cancer.