Bruce D. Trapp

Differentiation and death of premyelinating oligodendrocytes in developing rodent brain.

Expression of oligodendrocyte progenitor cell antigens by gliomas: implications for the histogenesis of brain tumors.

Axonal pathology in multiple sclerosis: relationship to neurologic disability.

P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves.

Axo-glial septate junctions. The maestro of nodal formation and myelination?

Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences.

N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve.

Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis.

Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis.

VCAM-1-positive microglia target oligodendrocytes at the border of multiple sclerosis lesions.

Treatment of experimental autoimmune encephalomyelitis with the chemokine receptor antagonist Met-RANTES.

The tetraspanin protein, CD9, is expressed by progenitor cells committed to oligodendrogenesis and is linked to beta1 integrin, CD81, and Tspan-2.

Axonal degeneration and progressive neurologic disability in multiple sclerosis.

The 36K protein of zebrafish CNS myelin is a short-chain dehydrogenase.

Dysmyelinated lower motor neurons retract and regenerate dysfunctional synaptic terminals.

Neuropathobiology of multiple sclerosis.

Beta IV tubulin is selectively expressed by oligodendrocytes in the central nervous system.

Taking two TRAILS.

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients.

Evolution of a neuroprotective function of central nervous system myelin.

A dual tyrosine-leucine motif mediates myelin protein P0 targeting in MDCK cells.

N-acetyl-L-aspartate in multiple sclerosis.

[Pathology and definition of multiple sclerosis].

Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases.

Bace1 modulates myelination in the central and peripheral nervous system.

Evidence for synaptic stripping by cortical microglia.

Pathogenesis of axonal and neuronal damage in multiple sclerosis.

Activation of the ciliary neurotrophic factor (CNTF) signalling pathway in cortical neurons of multiple sclerosis patients.

Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves.

Rescue of congenital hypomyelination by progenitor cell transplantation.

Preconditioning paradigms and pathways in the brain.

Multiple sclerosis: an immune or neurodegenerative disorder?

P0 protein is required for and can induce formation of schmidt-lantermann incisures in myelin internodes.

Neurogenesis in the chronic lesions of multiple sclerosis.

Imaging correlates of leukocyte accumulation and CXCR4/CXCL12 in multiple sclerosis.

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis.

Beta4 tubulin identifies a primitive cell source for oligodendrocytes in the mammalian brain.

Human myelin proteome and comparative analysis with mouse myelin.

NG2-positive glia in the human central nervous system.

Gray-matter injury in multiple sclerosis.

The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination.

Demyelination increases axonal stationary mitochondrial size and the speed of axonal mitochondrial transport.

Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis.

Gene expression profiling in multiple sclerosis brain.

Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients.

Cleavage of neuregulin-1 by BACE1 or ADAM10 protein produces differential effects on myelination.

Myelination and axonal electrical activity modulate the distribution and motility of mitochondria at CNS nodes of Ranvier.

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis.

Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4.

Cortical remyelination: a new target for repair therapies in multiple sclerosis.

Clinically feasible MTR is sensitive to cortical demyelination in MS.

Lessons from Jack Griffin and the "pathogenesis of peripheral nerve disease".

High spatial and angular resolution diffusion-weighted imaging reveals forniceal damage related to memory impairment.

Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors.

Activated microglia enhance neurogenesis via trypsinogen secretion.

Biology of Schwann cells.

Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells.

Epigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains.

Axonal loss in multiple sclerosis: causes and mechanisms.

Hippocampal volume is related to cognitive decline and fornicial diffusion measures in multiple sclerosis.

Relapsing and progressive forms of multiple sclerosis: insights from pathology.

Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons.

Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain.

Proteolipid protein cannot replace P0 protein as the major structural protein of peripheral nervous system myelin.

Discrepancy in CCL2 and CCR2 expression in white versus grey matter hippocampal lesions of Multiple Sclerosis patients.

Mitochondrial fission augments capsaicin-induced axonal degeneration.

Microglia and neuroprotection.

Cuprizone does not induce CNS demyelination in nonhuman primates.

Pathological mechanisms in progressive multiple sclerosis.

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis.

The relationship between cognitive function and high-resolution diffusion tensor MRI of the cingulum bundle in multiple sclerosis.

Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination.

Relapses in multiple sclerosis: Relationship to disability.

Is Axonal Degeneration a Key Early Event in Parkinson's Disease?

Proteolipid protein-deficient myelin promotes axonal mitochondrial dysfunction via altered metabolic coupling.

Discovery of 1,2,3-Triazole Derivatives for Multimodality PET/CT/Cryoimaging of Myelination in the Central Nervous System.

GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system.

BACE1 regulates the proliferation and cellular functions of Schwann cells.

Integrin-Kindlin3 requirements for microglial motility in vivo are distinct from those for macrophages.

DNA methylation in demyelinated multiple sclerosis hippocampus.

T1-/T2-weighted ratio differs in demyelinated cortex in multiple sclerosis.

Alterations in CA1 hippocampal synapses in a mouse model of fragile X syndrome.

MR Imaging-based Estimation of Upper Motor Neuron Density in Patients with Amyotrophic Lateral Sclerosis: A Feasibility Study.

A histone deacetylase 3-dependent pathway delimits peripheral myelin growth and functional regeneration.

The role of the thalamus and hippocampus in episodic memory performance in patients with multiple sclerosis.

Much, if not all, of the cortical damage in MS can be attributed to the microglial cell - No.

Lateral cerebellar nucleus stimulation promotes motor recovery and suppresses neuroinflammation in a fluid percussion injury rodent model.

Cortical neuronal densities and cerebral white matter demyelination in multiple sclerosis: a retrospective study.

Identifying a new subtype of multiple sclerosis.

pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis.

Brain fibrinogen deposition plays a key role in MS pathophysiology - Yes.