David Stern

The assessment of Global Minimum Essential Requirements in medical education.

A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation.

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.

More than a marker... Phosphorylated Akt in prostate carcinoma.

Antisense transcript and RNA processing alterations suppress instability of polyadenylated mRNA in chlamydomonas chloroplasts.

Exploring professional values and health policy through Photovoice.

ErbB2 is required for ductal morphogenesis of the mammary gland.

Global sulfur emissions from 1850 to 2000.

Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily.

Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage.

The prediction of professional behaviour.

Interaction of chromatin-associated Plk1 and Mcm7.

Atherosclerosis and restenosis: is there a role for RAGE?

Climate variability and malaria epidemics in the highlands of East Africa.

ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction.

Beyond complementation. Map-based cloning in Chlamydomonas reinhardtii.

Microarray analysis confirms the specificity of a Chlamydomonas reinhardtii chloroplast RNA stability mutant.

Regulation of CHK2 by DNA-dependent protein kinase.

Trading health services across borders: GATS, markets, and caveats.

Chronic vascular inflammation in patients with type 2 diabetes: endothelial biopsy and RT-PCR analysis.

Healing a broken heart with stem cells.

Natural selection and developmental constraints in the evolution of allometries.

Bedside interactions from the other side of the bedrail.

Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients.

Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease.

Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.

Genetic variation for an aphid wing polyphenism is genetically linked to a naturally occurring wing polymorphism.

Initial use of a novel instrument to measure professionalism in surgical residents.

The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.

The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2.

RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling.

RNR1, a 3'-5' exoribonuclease belonging to the RNR superfamily, catalyzes 3' maturation of chloroplast ribosomal RNAs in Arabidopsis thaliana.

The economic impact of quarantine: SARS in Toronto as a case study.

Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-beta peptide alcohol dehydrogenase (ABAD).

The origin of a mutualism: a morphological trait promoting the evolution of ant-aphid mutualisms.

A spontaneous tRNA suppressor of a mutation in the Chlamydomonas reinhardtii nuclear MCD1 gene required for stability of the chloroplast petD mRNA.

Neuregulin-regulated gene expression in mammary carcinoma cells.

Tissue factor as a link between wounding and tissue repair.

Ensuring global standards for medical graduates: a pilot study of international standard-setting.

Advanced glycation end product receptor-mediated cellular dysfunction.

The nature of qualitative comments in evaluating professionalism.

Phosphoproteomics for oncology discovery and treatment.

The temporal requirements for insulin signaling during development in Drosophila.

Medical students' views on peer assessment of professionalism.

Understanding RAGE, the receptor for advanced glycation end products.

DNA damage regulates Chk2 association with chromatin.

Maximizing participation in peer assessment of professionalism: the students speak.

Phosphorylated/activated HER2 as a marker of clinical resistance to single agent taxane chemotherapy for metastatic breast cancer.

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.

The marriage of glucose and blood vessels: it isn't all that sweet.

Hyperglycemia and reactive oxygen species mediate apoptosis in aortic endothelial cells through Janus kinase 2.

Pleiotropic functions of a conserved insect-specific Hox peptide motif.

In situ detection of specific DNA double strand breaks using rolling circle amplification.

RAGE and its ligands: a lasting memory in diabetic complications?

Global analysis of protein phosphorylation in yeast.

Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1.

Disciplinary action by medical boards and prior behavior in medical school.

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss.

Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells.

Setting school-level outcome standards.

Chlamydomonas reinhardtii encodes a single sigma70-like factor which likely functions in chloroplast transcription.

Adaptive evolution of chloroplast genome structure inferred using a parametric bootstrap approach.

High-resolution quantitative trait locus mapping reveals sign epistasis controlling ovariole number between two Drosophila species.

Role of the JAK/STAT signaling pathway in diabetic nephropathy.

A dual-genome microarray for the pea aphid, Acyrthosiphon pisum, and its obligate bacterial symbiont, Buchnera aphidicola.

Large-scale gene discovery in the pea aphid Acyrthosiphon pisum (Hemiptera).

Regulation of osteoclast function and bone mass by RAGE.

Carbazole is a naturally occurring inhibitor of angiogenesis and inflammation isolated from antipsoriatic coal tar.

Nuclear suppressors define three factors that participate in both 5' and 3' end processing of mRNAs in Chlamydomonas chloroplasts.

The sulfur acclimation SAC3 kinase is required for chloroplast transcriptional repression under sulfur limitation in Chlamydomonas reinhardtii.

Are we making progress in medical education?

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.

A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies).

Developmental biology. Morphing into shape.

The pea aphid, Acyrthosiphon pisum: an emerging genomic model system for ecological, developmental and evolutionary studies.

Mitochondrial amyloid-beta peptide: pathogenesis or late-phase development?

Ethics and professionalism: what does a resident need to learn?

Outside the classroom: teaching and evaluating future physicians.

Posttranslationally modified proteins as mediators of sustained intestinal inflammation.

The developing physician--becoming a professional.

Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation.

RAGE in inflammation: a new therapeutic target?

The nucleus-encoded factor MCD4 participates in degradation of nonfunctional 3' UTR sequences generated by cleavage of pre-mRNA in Chlamydomonas chloroplasts.

Mitochondrial dysfunction and Alzheimer's disease.

A new protocol for quantifying CD34(+) cells in peripheral blood of patients with cardiovascular disease.

Integration of chloroplast nucleic acid metabolism into the phosphate deprivation response in Chlamydomonas reinhardtii.

Rubisco large-subunit translation is autoregulated in response to its assembly state in tobacco chloroplasts.

Prevalence of Cryptosporidium species in wildlife populations within a watershed landscape in southeastern New York State.

Can there be a single system for peer assessment of professionalism among medical students? A multi-institutional study.

Patients speak: what's really important about bedside interactions with physician teams.

Granulocyte colony-stimulating factor has a negative effect on stroke outcome in a murine model.

Morphological evolution through multiple cis-regulatory mutations at a single gene.

Soluble forms of RAGE: an index of vascular stress? A commentary on "Soluble RAGE in type 2 diabetes: association with oxidative stress".

The function and regulation of Ultrabithorax in the legs of Drosophila melanogaster.

Common genome-wide patterns of transcript accumulation underlying the wing polyphenism and polymorphism in the pea aphid (Acyrthosiphon pisum).

Variation in fiber number of a male-specific muscle between Drosophila species: a genetic and developmental analysis.

Hippocampal CA1 cell loss in a non-human primate model of transient global ischemia: a pilot study.

Circulating CD34-positive cells provide a marker of vascular risk associated with cognitive impairment.

Evolution. An embarrassment of switches.

The developmental genetics of microevolution.

The Chlamydomonas genome reveals the evolution of key animal and plant functions.

Nuclear, chloroplast, and mitochondrial transcript abundance along a maize leaf developmental gradient.

Peer nomination: a tool for identifying medical student exemplars in clinical competence and caring, evaluated at three medical schools.

Internal and external constraints in the evolution of morphological allometries in a butterfly.

Angiotensin II-induced signaling pathways in diabetes.

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans.

Pelvic cancer ten years after restorative proctocolectomy in indeterminate colitis: report of a case.

Production of antibodies that recognize specific tyrosine-phosphorylated peptides.

Increase in circulating CD34-positive cells in patients with angiographic evidence of moyamoya-like vessels.

Outcome-based national profile of Mexico's medical graduates.

The outcomes of global minimum essential requirements (GMER) pilot implementation in China.

Regulation of the Rad53 protein kinase in signal amplification by oligomer assembly and disassembly.

International medical school faculty development: the results of a needs assessment survey among medical educators in China.

Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.

Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: study 8541 from the Cancer and Leukemia Group B.

Direct resequencing of the complete ERBB2 coding sequence reveals an absence of activating mutations in ERBB2 amplified breast cancer.

Production of antibodies that recognize specific tyrosine-phosphorylated peptides.

ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer.

Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice.

Quality of life, optimism/pessimism, and knowledge and attitudes toward HIV Screening among pregnant women in Ghana.

Genome-based analysis of Chlamydomonas reinhardtii exoribonucleases and poly(A) polymerases predicts unexpected organellar and exosomal features.

Tinker where the tinkering's good.

Aphids.

The loci of evolution: how predictable is genetic evolution?

Behavioral telemonitoring: the next frontier of senior care management.

Circulating CD34-positive cells have prognostic value for neurologic function in patients with past cerebral infarction.

Critical events in the lives of interns.

Teaching humanism.

NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway.

ErbB3 is required for ductal morphogenesis in the mouse mammary gland.

The RNA-binding proteins CSP41a and CSP41b may regulate transcription and translation of chloroplast-encoded RNAs in Arabidopsis.

Response to medical students' letter of solidarity with Gaza.

BRCTing up is hard to do.

Is genetic evolution predictable?

RNA polyadenylation and decay in mitochondria and chloroplasts.

Insect-machine interface based neurocybernetics.

Endothelial precursor cells and CRP on the RAGE: activation or cell death?

Polyadenylation in Arabidopsis and Chlamydomonas organelles: the input of nucleotidyltransferases, poly(A) polymerases and polynucleotide phosphorylase.

RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation?

How different are recently diverged species?: more than 150 phenotypic differences have been reported for the D. melanogaster species subgroup.

Similar patterns of linkage disequilibrium and nucleotide diversity in native and introduced populations of the pea aphid, Acyrthosiphon pisum.

Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice.

Anomaly in aortic arch alters pathological outcome of transient global ischemia in Rhesus macaques.

Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction.

Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection.

C. elegans as model for the study of high glucose- mediated life span reduction.

Abnormal physiological and molecular mutant phenotypes link chloroplast polynucleotide phosphorylase to the phosphorus deprivation response in Arabidopsis.

Progenitor cells from the explanted heart generate immunocompatible myocardium within the transplanted donor heart.

Dynamics of genome evolution in facultative symbionts of aphids.

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction.

RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.

Evolution of the tan locus contributed to pigment loss in Drosophila santomea: a response to Matute et al.

Transgenic maize lines with cell-type specific expression of fluorescent proteins in plastids.

Genetic deficiency of Irgm1 (LRG-47) suppresses induction of experimental autoimmune encephalomyelitis by promoting apoptosis of activated CD4+ T cells.

A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival.

MRL1, a conserved Pentatricopeptide repeat protein, is required for stabilization of rbcL mRNA in Chlamydomonas and Arabidopsis.

Injury-induced neural stem/progenitor cells in post-stroke human cerebral cortex.

Insights into the evolution of mitochondrial genome size from complete sequences of Citrullus lanatus and Cucurbita pepo (Cucurbitaceae).

Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs.

Chloroplast RNA metabolism.

Michael Akam and the rise of evolutionary developmental biology.

Increased incidence of gastrointestinal bleeding following implantation of the HeartMate II LVAD.

Sex and death in the male pea aphid, Acyrthosiphon pisum: The life-history effects of a wing dimorphism.

Apurinic/apyrimidinic endonuclease 1, p53, and thioredoxin are linked in control of aging in C. elegans.

Telmisartan suppresses cerebral injury in a murine model of transient focal ischemia.

Use of Illumina sequencing to identify transposon insertions underlying mutant phenotypes in high-copy Mutator lines of maize.

Mechanical support for postcardiotomy cardiogenic shock: has progress been made?

Phenotypic robustness conferred by apparently redundant transcriptional enhancers.

Differential replication of two chloroplast genome forms in heteroplasmic Chlamydomonas reinhardtii gametes contributes to alternative inheritance patterns.

Centrosomal Chk2 in DNA damage responses and cell cycle progression.

Immunodeficiency reduces neural stem/progenitor cell apoptosis and enhances neurogenesis in the cerebral cortex after stroke.

Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways.

Reduced ischemic brain injury by partial rejuvenation of bone marrow cells in aged rats.

A Reproducible and Simple Model of Permanent Cerebral Ischemia in CB-17 and SCID Mice.

What factors create a humanistic doctor? A nationwide survey of fourth-year medical students.

Overexpression of a natural chloroplast-encoded antisense RNA in tobacco destabilizes 5S rRNA and retards plant growth.

EGFs and ERBBs--brief history and prospects.

Congenitally corrected transposition of the great arteries and concomitant coronary artery and valvular disease in the adult patient.

Expanding policy options for educating teenagers.

Overaccumulation of the chloroplast antisense RNA AS5 is correlated with decreased abundance of 5S rRNA in vivo and inefficient 5S rRNA maturation in vitro.

Developmental and cell type characterization of bundle sheath and mesophyll chloroplast transcript abundance in maize.

Multiplexed shotgun genotyping for rapid and efficient genetic mapping.

Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.

The role of energy in economic growth.

Mutational analysis of Arabidopsis chloroplast polynucleotide phosphorylase reveals roles for both RNase PH core domains in polyadenylation, RNA 3'-end maturation and intron degradation.

Phosphoproteomic screen identifies potential therapeutic targets in melanoma.

NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53.

"Competence" progress.

Career development of physician scientists: a survey of leaders in academic medicine.

Follow the leader.

Morphological evolution caused by many subtle-effect substitutions in regulatory DNA.

Preparation of cuticles from unhatched first-instar Drosophila larvae.

Temperature and malaria trends in highland East Africa.

Dynamics of genome evolution in facultative symbionts of aphids.

Chloroplast RNase J compensates for inefficient transcription termination by removal of antisense RNA.

Cilostazol reduces the risk of hemorrhagic infarction after administration of tissue-type plasminogen activator in a murine stroke model.

Preparation of cuticles from feeding Drosophila larvae.

Rapid mounting of adult Drosophila structures in Hoyer's medium.

Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain.