Etienne Sibille

Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression.

Elevated Hippocampal Cholinergic Neurostimulating Peptide precursor protein (HCNP-pp) mRNA in the amygdala in major depression.

Hypermethylation of BDNF and SST Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age.

FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk.

Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis.

Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology.

Age-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex.

Decrease in somatostatin-positive cell density in the amygdala of females with major depression.

Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype.

A Neural "Tuning Curve" for Multisensory Experience and Cognitive-Perceptual Schizotypy.

Reduced Somatostatin Expression or Somatostatin-Positive Gamma-Aminobutyric Acid Neurons: A Shared Pathology Across Brain Disorders.

Somatostatin-Positive Gamma-Aminobutyric Acid Interneuron Deficits in Depression: Cortical Microcircuit and Therapeutic Perspectives.

Resilient protein co-expression network in male orbitofrontal cortex layer 2/3 during human aging.

Characterization of GABAergic marker expression in the chronic unpredictable stress model of depression.

Sustained Molecular Pathology Across Episodes and Remission in Major Depressive Disorder.

Fluorescence-based cell-specific detection for laser-capture microdissection in human brain.

Cross-Laboratory Analysis of Brain Cell Type Transcriptomes with Applications to Interpretation of Bulk Tissue Data.

Increased Neuronal DNA/RNA Oxidation in the Frontal Cortex of Mice Subjected to Unpredictable Chronic Mild Stress.

Identification of a novel gene regulating amygdala-mediated fear extinction.

Shifting priorities: highly conserved behavioral and brain network adaptations to chronic stress across species.

Opposite Molecular Signatures of Depression in Men and Women.

The Relative Contributions of Cell-Dependent Cortical Microcircuit Aging to Cognition and Anxiety.

The Role of Dendritic Brain-Derived Neurotrophic Factor Transcripts on Altered Inhibitory Circuitry in Depression.

DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions.

Cell Type-Specific Gene Expression of Alpha 5 Subunit-Containing Gamma-Aminobutyric Acid Subtype A Receptors in Human and Mouse Frontal Cortex.

Residual avoidance: A new, consistent and repeatable readout of chronic stress-induced conflict anxiety reversible by antidepressant treatment.

Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive Profiles.

Molecular and Cellular Evidence for Age by Disease Interactions: Updates and Path Forward.

Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders.

Chronic Stress-induced Behaviors Correlate with Exacerbated Acute Stress-induced Cingulate Cortex and Ventral Hippocampus Activation.

Older molecular brain age in severe mental illness.

Synthesis of chiral GABA receptor subtype selective ligands as potential agents to treat schizophrenia as well as depression.

Transcriptional markers of excitation-inhibition balance in germ-free mice show region-specific dysregulation and rescue after bacterial colonization.

Large-Scale Transcriptomics Studies Provide Insight Into Sex Differences in Depression.

BDNF controls GABAR trafficking and related cognitive processes via autophagic regulation of p62.

From serendipity to rational drug design in brain disorders: in silico, in vitro, and in vivo approaches.

Cortical GABA neurons and self-focus in depression: a model linking cellular, biochemical and neural network findings.

Sex differences in mood disorders: perspectives from humans and rodent models.

VSNL1 Co-Expression Networks in Aging Include Calcium Signaling, Synaptic Plasticity, and Alzheimer's Disease Pathways.

Molecular and Genetic Characterization of Depression: Overlap with other Psychiatric Disorders and Aging.

Effects of aging on circadian patterns of gene expression in the human prefrontal cortex.

α5GABAA receptor deficiency causes autism-like behaviors.

The Role of BDNF in Age-Dependent Changes of Excitatory and Inhibitory Synaptic Markers in the Human Prefrontal Cortex.

Sigma-1 and N-Methyl-d-Aspartate Receptors: A Partnership with Beneficial Outcomes.

Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABA Receptor Positive Allosteric Modulator.

Norepinephrine Transporter Gene Variants and Remission From Depression With Venlafaxine Treatment in Older Adults.

Genetic risk for schizophrenia and psychosis in Alzheimer disease.

Reduced GABAergic cortical inhibition in aging and depression.

Expression of dopamine D2 and D3 receptors in the human retina revealed by positron emission tomography and targeted mass spectrometry.

Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons.

No interaction between polygenic scores and childhood trauma in predicting suicide attempt in schizophrenia.

Insight into Novel Treatment for Cognitive Dysfunctions across Disorders.

Rate of brain aging and are synergistic risk factors for Alzheimer's disease.

Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults.

Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation.

Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms.

Differential and spatial expression meta-analysis of genes identified in genome-wide association studies of depression.

Behavioral Deficits Induced by Somatostatin-Positive GABA Neuron Silencing Are Rescued by Alpha 5 GABA-A Receptor Potentiation.

Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response.

Correction: Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms.

Estimating and Correcting for Off-Target Cellular Contamination in Brain Cell Type Specific RNA-Seq Data.

Reduced anterior cingulate cortex volume induced by chronic stress correlates with increased behavioral emotionality and decreased synaptic puncta density.

Chronic Stress Alters Astrocyte Morphology in Mouse Prefrontal Cortex.

Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk.

Molecular characterization of depression trait and state.

Chronic Stress Induces Coordinated Cortical Microcircuit Cell-Type Transcriptomic Changes Consistent With Altered Information Processing.

Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits.

Molecular origin of somatostatin-positive neuron vulnerability.

Lower Levels of GABAergic Function Markers in Corticotropin-Releasing Hormone-Expressing Neurons in the sgACC of Human Subjects With Depression.

Symptomatic and neurotrophic effects of GABAA receptor positive allosteric modulation in a mouse model of chronic stress.

Positive Allosteric Modulation of α5-GABAA Receptors Reverses Stress-Induced Alterations in Dopamine System Function and Prepulse Inhibition of Startle.

Neurotrophic effects of potentiating gaba-mediated dendritic inhibition.

Hippocampal α5-GABA Receptors Modulate Dopamine Neuron Activity in the Rat Ventral Tegmental Area.

Transcriptomic congruence analysis for evaluating model organisms.

Robust differences in cortical cell type proportions across healthy human aging inferred through cross-dataset transcriptome analyses.

Prophylactic Efficacy of Riluzole against Anxiety- and Depressive-Like Behaviors in Two Rodent Stress Models.