Gabriella Sozzi

Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines.

Molecular changes track recurrence and progression of bronchial precancerous lesions.

Involvement of FHIT in lung carcinogenesis prospects for future clinical gene therapy applications.

p16(INK4A) Hypermethylation detected by fluorescent methylation-specific PCR in plasmas from non-small cell lung cancer.

UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.

Evidence of neural differentiation in a case of post-therapy primitive neuroectodermal tumor/Ewing sarcoma of bone.

Quantification of free circulating DNA as a diagnostic marker in lung cancer.

Detecting lung cancer in plasma with the use of multiple genetic markers.

Molecular cytogenetic characterization of proximal-type epithelioid sarcoma.

Dose-dependent effect of FHIT-inducible expression in Calu-1 lung cancer cell line.

Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14.

Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma.

The apoptotic pathway triggered by the Fhit protein in lung cancer cell lines is not affected by Bcl-2 or Bcl-x(L) overexpression.

Reduced FEZ1/LZTS1 expression and outcome prediction in lung cancer.

Bilateral preaxial polydactyly in a WAGR syndrome patient.

Reproducibility of a semiquantitative measurement of circulating DNA in plasma from neoplastic patients.

SMARCB1/INI1 tumor suppressor gene is frequently inactivated in epithelioid sarcomas.

Methylation profile in tumor and sputum samples of lung cancer patients detected by spiral computed tomography: a nested case-control study.

Detecting cell-free circulating hTERT mRNA in the plasma may identify a subset of nonsmall cell lung cancer patients.

Wilms tumor in monozygous twins: clinical, pathological, cytogenetic and molecular case report.

Effects of prolonged storage of whole plasma or isolated plasma DNA on the results of circulating DNA quantification assays.

Diadenosines as FHIT-ness instructors.

Salvage treatment for childhood ependymoma after surgery only: Pitfalls of omitting "at once" adjuvant treatment.

Quantitative analysis of plasma DNA in colorectal cancer patients: a novel prognostic tool.

Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics.

Fragile histidine triad expression in oral squamous cell carcinoma and precursor lesions.

Non-chromosome 11-p syndromes in Wilms tumor patients: Clinical and cytogenetic report of two Down syndrome cases and one Turner syndrome case.

Radiation effects on development of HER2-positive breast carcinomas.

The role of chromosomal alterations in human cancer development.

Plasma DNA quantification in lung cancer computed tomography screening: five-year results of a prospective study.

Fragile histidine triad gene inactivation in lung cancer: the European Early Lung Cancer project.

EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues.

Prolonged remission of disseminated atypical adenomatous hyperplasia under gefitinib.

Tumor-initiating cells of HER2-positive carcinoma cell lines express the highest oncoprotein levels and are sensitive to trastuzumab.

IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions.

The EML4-ALK transcript but not the fusion protein can be expressed in reactive and neoplastic lymphoid tissues.

Plasma DNA levels in spiral CT-detected and clinically detected lung cancer patients: a validation analysis.

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment.

Fluorodeoxyglucose uptake measured by positron emission tomography and standardized uptake value predicts long-term survival of CT screening detected lung cancer in heavy smokers.

Elevated levels of the acute-phase serum amyloid are associated with heightened lung cancer risk.

Molecular cytogenetic characterization of stem-like cancer cells isolated from established cell lines.

Prognostic determinants in epithelioid sarcoma.

Treatment of chondral defects of the knee with one step matrix-assisted technique enhanced by autologous concentrated bone marrow: in vitro characterisation of mesenchymal stem cells from iliac crest and subchondral bone.

MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer.

MicroRNAs and lung cancer: from markers to targets.

Inactivation of both FHIT and p53 cooperate in deregulating proliferation-related pathways in lung cancer.

Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial.

Progressive lung cancer determined by expression profiling and transcriptional regulation.

Patient-derived xenografts of non small cell lung cancer: resurgence of an old model for investigation of modern concepts of tailored therapy and cancer stem cells.

Role of microRNAs in lung cancer: microRNA signatures in cancer prognosis.

Multiparametric molecular characterization of pulmonary sarcomatoid carcinoma reveals a nonrandom amplification of anaplastic lymphoma kinase (ALK) gene.

Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysis.

Clinical utility of a plasma-based miRNA signature classifier within computed tomography lung cancer screening: a correlative MILD trial study.

Assessment of circulating microRNAs in plasma of lung cancer patients.

YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes.

Ewing sarcoma of the small bowel: a study of seven cases, including one with the uncommonly reported EWSR1-FEV translocation.

Therapeutic use of microRNAs in lung cancer.

Potential biomarkers for lung cancer screening.

Recent advances of microRNA-based molecular diagnostics to reduce false-positive lung cancer imaging.

Combination Treatment with All-Trans Retinoic Acid Prevents Cisplatin-Induced Enrichment of CD133+ Tumor-Initiating Cells and Reveals Heterogeneity of Cancer Stem Cell Compartment in Lung Cancer.

Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis.

Gene Signatures Stratify Computed Tomography Screening Detected Lung Cancer in High-Risk Populations.

Circulating microRNA signature as liquid-biopsy to monitor lung cancer in low-dose computed tomography screening.

Novel method to detect microRNAs using chip-based QuantStudio 3D digital PCR.

Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells.

IL12RB2 Polymorphisms correlate with risk of lung adenocarcinoma.

Synergistic Activation upon MET and ALK Coamplification Sustains Targeted Therapy in Sarcomatoid Carcinoma, a Deadly Subtype of Lung Cancer.

Screening with Low-Dose Computed Tomography Does Not Improve Survival of Small Cell Lung Cancer.

Stopping Smoking Reduces Mortality in Low-Dose Computed Tomography Screening Participants.

[Lung cancer screening in high-risk subjects: early detection with LDCT and risk stratification using miRNA-based blood test].

Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes.

Lung cancer screening with low-dose spiral computed tomography: evidence from a pooled analysis of two Italian randomized trials.

Anaplastic lymphoma kinase aberrations correlate with metastatic features in pediatric rhabdomyosarcoma.

MicroRNA Profile of Lung Tumor Tissues Is Associated with a High Risk Plasma miRNA Signature.

CDCP1 is a novel marker of the most aggressive human triple-negative breast cancers.

Metabolic Evaluation of Non-Small Cell Lung Cancer Patient-Derived Xenograft Models Using 18F-FDG PET: A Potential Tool for Early Therapy Response.

Early Effector T Lymphocytes Coexpress Multiple Inhibitory Receptors in Primary Non-Small Cell Lung Cancer.

GENOMIC PROFILING OF PATIENT-DERIVED XENOGRAFTS FOR LUNG CANCER IDENTIFIES B2M INACTIVATION IMPAIRING IMMUNORECOGNITION.

LKB1 Expression Correlates with Increased Survival in Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy and Bevacizumab.

mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis.

Mutational Profile from Targeted NGS Predicts Survival in LDCT Screening-Detected Lung Cancers.

Genomic Profiling of Patient-Derived Xenografts for Lung Cancer Identifies B2M Inactivation Impairing Immunorecognition.

Inflammatory status and lung function predict mortality in lung cancer screening participants.

Detection of microRNAs Using Chip-Based QuantStudio 3D Digital PCR.

Baseline and postoperative C-reactive protein levels predict mortality in operable lung cancer.

Establishment of patient derived xenografts as functional testing of lung cancer aggressiveness.