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Department of Pharmacological Sciences
Holly Colognato has not added Biography.
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CNS integrins switch growth factor signalling to promote target-dependent survival.
Nature cell biology Nov, 2002 | Pubmed ID: 12379866
Regulation of integrin growth factor interactions in oligodendrocytes by lipid raft microdomains.
Current biology : CB Jan, 2003 | Pubmed ID: 12546790
Mechanisms of glial development.
Current opinion in neurobiology Feb, 2004 | Pubmed ID: 15018936
Neuroscience. The mysteries of myelin unwrapped.
Science (New York, N.Y.) Apr, 2004 | Pubmed ID: 15118149
Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development.
The Journal of cell biology Oct, 2004 | Pubmed ID: 15504915
Integrins: versatile integrators of extracellular signals.
Trends in cell biology Dec, 2004 | Pubmed ID: 15564044
Integrin-growth factor interactions as regulators of oligodendroglial development and function.
Glia Mar, 2005 | Pubmed ID: 15578662
Human diseases reveal novel roles for neural laminins.
Trends in neurosciences Sep, 2005 | Pubmed ID: 16043237
Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2006 | Pubmed ID: 16855094
Contrasting effects of mitogenic growth factors on myelination in neuron-oligodendrocyte co-cultures.
Glia Apr, 2007 | Pubmed ID: 17236210
Identification of dystroglycan as a second laminin receptor in oligodendrocytes, with a role in myelination.
Development (Cambridge, England) May, 2007 | Pubmed ID: 17395644
Beta1 integrins are required for normal CNS myelination and promote AKT-dependent myelin outgrowth.
Development (Cambridge, England) Aug, 2009 | Pubmed ID: 19633169
beta1 integrin maintains integrity of the embryonic neocortical stem cell niche.
PLoS biology Aug, 2009 | Pubmed ID: 19688041
Laminin alters fyn regulatory mechanisms and promotes oligodendrocyte development.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2009 | Pubmed ID: 19776266
Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development.
Journal of neurochemistry Apr, 2010 | Pubmed ID: 20132481
Dystroglycan modulates the ability of insulin-like growth factor-1 to promote oligodendrocyte differentiation.
Journal of neuroscience research Nov, 2010 | Pubmed ID: 20857503
Glia unglued: how signals from the extracellular matrix regulate the development of myelinating glia.
Developmental neurobiology Nov, 2011 | Pubmed ID: 21834081
Dystroglycan promotes filopodial formation and process branching in differentiating oligodendroglia.
Journal of neurochemistry Nov, 2011 | Pubmed ID: 22117643
Stony Brook University
Ryan W. O'Meara1,2,
Scott D. Ryan1,
Holly Colognato3,
Rashmi Kothary1,2,4
1Regenerative Medicine Program, Ottawa Hospital Research Institute,
2Department of Cellular and Molecular Medicine, University of Ottawa ,
3Department of Pharmacological Sciences, Stony Brook University,
4Department of Medicine, University of Ottawa
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