Jan Lammerding

Signaling pathways that influence extracellular remodeling.

Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengthening.

A three-dimensional viscoelastic model for cell deformation with experimental verification.

Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction.

Mechanotransduction in cardiac myocytes.

The nuclear membrane and mechanotransduction: impaired nuclear mechanics and mechanotransduction in lamin A/C deficient cells.

Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells.

Focal adhesion kinase signaling regulates cardiogenesis of embryonic stem cells.

Prelamin A and lamin A appear to be dispensable in the nuclear lamina.

Lamins A and C but not lamin B1 regulate nuclear mechanics.

Cell nuclei spin in the absence of lamin b1.

Torn apart: membrane rupture in muscular dystrophies and associated cardiomyopathies.

Nuclear mechanics and methods.

Towards an integrated understanding of the structure and mechanics of the cell nucleus.

Increased mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells: effects of farnesyltransferase inhibitors.

Experimental techniques for study of chromatin mechanics in intact nuclei and living cells.

Nuclear shape, mechanics, and mechanotransduction.

Mechanical properties of interphase nuclei probed by cellular strain application.

Mechanotransduction gone awry.

Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy.

Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins.

Three-dimensional cardiac architecture determined by two-photon microtomy.

Attenuated hypertrophic response to pressure overload in a lamin A/C haploinsufficiency mouse.

Another broken heart: loss of lamina-associated polypeptide 2alpha causes systolic dysfunction.

An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.

Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice.

Altered mechanical properties of the nucleus in disease.

Nuclear mechanics during cell migration.

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect.

The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton.

Nuclear mechanics in disease.

Cell-surface sensors for real-time probing of cellular environments.

Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function.