Retina Service,
Angiogenesis Laboratory,
Department of Ophthalmology,
Retina Service, Angiogenesis Laboratory, Department of Ophthalmology
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Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment.
Archives of ophthalmology Mar, 2002 | Pubmed ID: 11879138
Localization of rose bengal, aluminum phthalocyanine tetrasulfonate, and chlorin e6 in the rabbit eye.
Retina (Philadelphia, Pa.) Feb, 2002 | Pubmed ID: 11884881
Expression of pigment epithelium-derived factor in experimental choroidal neovascularization.
Investigative ophthalmology & visual science May, 2002 | Pubmed ID: 11980876
Mechanisms of age-related macular degeneration.
Ophthalmology clinics of North America Mar, 2002 | Pubmed ID: 12064086
Verteporfin photodynamic therapy in the rat model of choroidal neovascularization: angiographic and histologic characterization.
Investigative ophthalmology & visual science Jul, 2002 | Pubmed ID: 12091441
Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: three-year results of an open-label extension of 2 randomized clinical trials--TAP Report no. 5.
Archives of ophthalmology Oct, 2002 | Pubmed ID: 12365909
Controlled delivery of the anti-VEGF aptamer EYE001 with poly(lactic-co-glycolic)acid microspheres.
Investigative ophthalmology & visual science Jan, 2003 | Pubmed ID: 12506087
Caspase activation in an experimental model of retinal detachment.
Investigative ophthalmology & visual science Mar, 2003 | Pubmed ID: 12601057
Improvement after verteporfin therapy.
Archives of ophthalmology Mar, 2003 | Pubmed ID: 12617718
Verteporfin therapy of subfoveal choroidal neovascularization in pathologic myopia: 2-year results of a randomized clinical trial--VIP report no. 3.
Ophthalmology Apr, 2003 | Pubmed ID: 12689884
Photodynamic therapy for choroidal neovascularization. The Jules Gonin Lecture, Montreux, Switzerland, 1 September 2002.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Apr, 2003 | Pubmed ID: 12719985
Management of dislocated lens material.
Seminars in ophthalmology Sep-Dec, 2002 | Pubmed ID: 12759846
Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization.
Investigative ophthalmology & visual science Jun, 2003 | Pubmed ID: 12766082
VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization.
The Journal of experimental medicine Aug, 2003 | Pubmed ID: 12900522
Acute severe visual acuity decrease after photodynamic therapy with verteporfin: case reports from randomized clinical trials-TAP and VIP report no. 3.
American journal of ophthalmology Apr, 2004 | Pubmed ID: 15059708
Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: meta-analysis of 2-year safety results in three randomized clinical trials: Treatment Of Age-Related Macular Degeneration With Photodynamic Therapy and Verteporfin In Photodynamic Therapy Study Report no. 4.
Retina (Philadelphia, Pa.) Feb, 2004 | Pubmed ID: 15076937
Extremely discordant sib-pair study design to determine risk factors for neovascular age-related macular degeneration.
Archives of ophthalmology Apr, 2004 | Pubmed ID: 15078676
Aptamers, intramers, and vascular endothelial growth factor.
International ophthalmology clinics , 2004 | Pubmed ID: 15211173
Anti-vascular endothelial growth factor strategies for the treatment of choroidal neovascularization from age-related macular degeneration.
International ophthalmology clinics , 2004 | Pubmed ID: 15211174
Ocular tissue permeabilities.
International ophthalmology clinics , 2004 | Pubmed ID: 15211177
Photosensitizers in photodynamic therapy of choroidal neovascularization.
International ophthalmology clinics , 2004 | Pubmed ID: 15211178
Treatment of chlamydial eye infections.
International ophthalmology clinics , 2004 | Pubmed ID: 15211182
Expression of leukocyte adhesion molecules in human subfoveal choroidal neovascular membranes treated with and without photodynamic therapy.
Investigative ophthalmology & visual science Jul, 2004 | Pubmed ID: 15223819
Selective photodynamic therapy by targeted verteporfin delivery to experimental choroidal neovascularization mediated by a homing peptide to vascular endothelial growth factor receptor-2.
Archives of ophthalmology Jul, 2004 | Pubmed ID: 15249365
Verteporfin in Photodynamic Therapy: report no. 5.
Ophthalmology Nov, 2004 | Pubmed ID: 15522385
FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment.
Investigative ophthalmology & visual science Dec, 2004 | Pubmed ID: 15557468
Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing.
Investigative ophthalmology & visual science Jan, 2005 | Pubmed ID: 15623796
An antisense oligodeoxynucleotide against vascular endothelial growth factor in a nonhuman primate model of iris neovascularization.
Archives of ophthalmology Feb, 2005 | Pubmed ID: 15710818
Safety and efficacy of intravitreal injection of ranibizumab in combination with verteporfin PDT on experimental choroidal neovascularization in the monkey.
Archives of ophthalmology Apr, 2005 | Pubmed ID: 15824225
Maximum tolerated dose of a humanized anti-vascular endothelial growth factor antibody fragment for treating neovascular age-related macular degeneration.
Ophthalmology Jun, 2005 | Pubmed ID: 15885778
Identification of Chlamydia pneumoniae within human choroidal neovascular membranes secondary to age-related macular degeneration.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Nov, 2005 | Pubmed ID: 15909160
Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin.
American journal of ophthalmology Sep, 2005 | Pubmed ID: 16139017
Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: four-year results of an open-label extension of 2 randomized clinical trials: TAP Report No. 7.
Archives of ophthalmology Sep, 2005 | Pubmed ID: 16157822
Medical treatment of choroidal neovascularization secondary to age-related macular degeneration.
International ophthalmology clinics , 2005 | Pubmed ID: 16199971
Effect of intravitreal injection of ranibizumab in combination with verteporfin PDT on normal primate retina and choroid.
Investigative ophthalmology & visual science Jan, 2006 | Pubmed ID: 16384985
Predictability and limitations of non-invasive murine tonometry: comparison of two devices.
Experimental eye research Jul, 2006 | Pubmed ID: 16564045
Investigating the effect of ciliary body photodynamic therapy in a glaucoma mouse model.
Investigative ophthalmology & visual science Jun, 2006 | Pubmed ID: 16723462
Dose-dependent effect of pitavastatin on VEGF and angiogenesis in a mouse model of choroidal neovascularization.
Investigative ophthalmology & visual science Jun, 2006 | Pubmed ID: 16723479
Histologic correlation of in vivo optical coherence tomography images of the human retina.
American journal of ophthalmology Jun, 2006 | Pubmed ID: 16765704
Predictors of visual outcome and choroidal neovascular membrane formation after traumatic choroidal rupture.
Archives of ophthalmology Jul, 2006 | Pubmed ID: 16832018
Using a drug before the risks and benefits are known from a phase 3 clinical trial: thoughts on compassion.
Archives of ophthalmology Jul, 2006 | Pubmed ID: 16832027
Characterization of cytokine responses to retinal detachment in rats.
Molecular vision , 2006 | Pubmed ID: 16917487
Potential future targets for treating ocular neovascularization.
Ophthalmology clinics of North America Sep, 2006 | Pubmed ID: 16935215
Proton beam irradiation for neovascular age-related macular degeneration.
Ophthalmology Nov, 2006 | Pubmed ID: 16935343
Identification of resident and inflammatory bone marrow derived cells in the sclera by bone marrow and haematopoietic stem cell transplantation.
The British journal of ophthalmology Apr, 2007 | Pubmed ID: 17035278
Introducing Evangelos S. Gragoudas, the 2006 recipient of the Weisenfeld Award.
Investigative ophthalmology & visual science Nov, 2006 | Pubmed ID: 17065471
Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2006 | Pubmed ID: 17151265
Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration.
Archives of ophthalmology Jan, 2007 | Pubmed ID: 17210851
Photodynamic therapy and combination treatments.
International ophthalmology clinics , 2007 | Pubmed ID: 17237676
Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2007 | Pubmed ID: 17284607
Infection, inflammation and age-related macular degeneration.
Clinical & experimental ophthalmology Jan-Feb, 2007 | Pubmed ID: 17300563
Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2007 | Pubmed ID: 17400913
The role of inflammation and infection in age-related macular degeneration.
International ophthalmology clinics , 2007 | Pubmed ID: 17450018
Reduced photoreceptor damage after photodynamic therapy through blockade of nitric oxide synthase in a model of choroidal neovascularization.
Investigative ophthalmology & visual science May, 2007 | Pubmed ID: 17460290
Attenuated glial reactions and photoreceptor degeneration after retinal detachment in mice deficient in glial fibrillary acidic protein and vimentin.
Investigative ophthalmology & visual science Jun, 2007 | Pubmed ID: 17525210
Endogenous endostatin inhibits choroidal neovascularization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2007 | Pubmed ID: 17526870
The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro.
Investigative ophthalmology & visual science Oct, 2007 | Pubmed ID: 17898295
Photodynamic therapy induces caspase-dependent apoptosis in rat CNV model.
Investigative ophthalmology & visual science Oct, 2007 | Pubmed ID: 17898299
Inhibition of vascular adhesion protein-1 suppresses endotoxin-induced uveitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2008 | Pubmed ID: 18032635
Anti-vascular endothelial growth factor therapy for ocular neovascular disease.
Current opinion in ophthalmology Nov, 2007 | Pubmed ID: 18163003
Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.
Ophthalmology Jul, 2008 | Pubmed ID: 18164066
In vivo imaging of endothelial injury in choriocapillaris during endotoxin-induced uveitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2008 | Pubmed ID: 18216288
Characterization of azurocidin as a permeability factor in the retina: involvement in VEGF-induced and early diabetic blood-retinal barrier breakdown.
Investigative ophthalmology & visual science Feb, 2008 | Pubmed ID: 18235021
DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity.
BMC medical genetics , 2008 | Pubmed ID: 18254956
Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1.
Investigative ophthalmology & visual science Jun, 2008 | Pubmed ID: 18296663
Photoreceptor protection after photodynamic therapy using dexamethasone in a rat model of choroidal neovascularization.
Investigative ophthalmology & visual science Nov, 2008 | Pubmed ID: 18421085
Pediatric ophthalmology. Preface.
International ophthalmology clinics , 2008 | Pubmed ID: 18427254
Vascular adhesion protein-1 blockade suppresses choroidal neovascularization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2008 | Pubmed ID: 18436961
Preliminary results of gene therapy for retinal degeneration.
The New England journal of medicine May, 2008 | Pubmed ID: 18441372
HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice.
The Journal of clinical investigation Jun, 2008 | Pubmed ID: 18497877
The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.
BMC medical genetics , 2008 | Pubmed ID: 18541031
Age-related macular degeneration.
The New England journal of medicine Jun, 2008 | Pubmed ID: 18550876
Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration.
Molecular vision , 2008 | Pubmed ID: 18704199
Ocular pathology. Preface.
International ophthalmology clinics , 2009 | Pubmed ID: 19125058
Higher irradiance and photodynamic therapy for age-related macular degeneration (an AOS thesis).
Transactions of the American Ophthalmological Society , 2008 | Pubmed ID: 19277246
Pharmacological inhibition of mitochondrial membrane permeabilization for neuroprotection.
Experimental neurology Aug, 2009 | Pubmed ID: 19303007
Seminars in Ophthalmology. Introduction.
Seminars in ophthalmology Mar-Apr, 2009 | Pubmed ID: 19373685
Review of the ocular angiogenesis animal models.
Seminars in ophthalmology Mar-Apr, 2009 | Pubmed ID: 19373687
Proliferative vitreoretinopathy: pathobiology and therapeutic targets.
Seminars in ophthalmology Mar-Apr, 2009 | Pubmed ID: 19373688
Review of anti-VEGF therapy in proliferative diabetic retinopathy.
Seminars in ophthalmology Mar-Apr, 2009 | Pubmed ID: 19373692
Molecular sequelae of histone deacetylase inhibition in human retinoblastoma cell lines: clinical implications.
Investigative ophthalmology & visual science Sep, 2009 | Pubmed ID: 19387079
Introduction.
Seminars in ophthalmology May-Jun, 2009 | Pubmed ID: 19437345
Judah Folkman.
Seminars in ophthalmology May-Jun, 2009 | Pubmed ID: 19437346
Role of alpha 4 integrin (CD49d) in the pathogenesis of diabetic retinopathy.
Investigative ophthalmology & visual science Oct, 2009 | Pubmed ID: 19553613
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach.
Vision research Mar, 2010 | Pubmed ID: 19786043
Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration.
American journal of ophthalmology Dec, 2009 | Pubmed ID: 19796758
A novel nonradioactive method to evaluate vascular barrier breakdown and leakage.
Investigative ophthalmology & visual science Mar, 2010 | Pubmed ID: 19875655
Legacy of the age-related eye disease [corrected] study.
Archives of ophthalmology Dec, 2009 | Pubmed ID: 20008728
Significant advances in cataract and refractive surgery over the last decade. Preface.
International ophthalmology clinics , 2010 | Pubmed ID: 20057290
Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2010 | Pubmed ID: 20371623
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2010 | Pubmed ID: 20385819
Reproducibility of retinal thickness measurements on normal and pathologic eyes by different optical coherence tomography instruments.
American journal of ophthalmology Dec, 2010 | Pubmed ID: 20965494
Fundus autofluorescence in geographic atrophy: a review.
Seminars in ophthalmology Sep-Nov, 2010 | Pubmed ID: 21091001
Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2010 | Pubmed ID: 21098270
Treatment of age-related macular degeneration: beyond VEGF.
Japanese journal of ophthalmology Nov, 2010 | Pubmed ID: 21191711
In vivo evaluation of laser-induced choroidal neovascularization using spectral-domain optical coherence tomography.
Investigative ophthalmology & visual science May, 2011 | Pubmed ID: 21296820
Edaravone, an ROS scavenger, ameliorates photoreceptor cell death after experimental retinal detachment.
Investigative ophthalmology & visual science May, 2011 | Pubmed ID: 21310909
Heat shock protein 70 (HSP70) is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase.
The American journal of pathology Mar, 2011 | Pubmed ID: 21356360
Displayed reflectivity of choroidal neovascular membranes by optical coherence tomography correlates with presence of leakage by fluorescein angiography.
Retina (Philadelphia, Pa.) May, 2011 | Pubmed ID: 21358457
Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment.
Investigative ophthalmology & visual science Mar, 2011 | Pubmed ID: 21402953
Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization.
PloS one , 2011 | Pubmed ID: 21559527
RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death.
Oncotarget Jun, 2011 | Pubmed ID: 21670490
Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics.
BMC medical genetics , 2011 | Pubmed ID: 21682878
Anti-vascular endothelial growth factor monotherapy versus combination treatment with photodynamic therapy for subfoveal choroidal neovascularization secondary to causes other than age-related macular degeneration.
Retina (Philadelphia, Pa.) Nov, 2011 | Pubmed ID: 21691258
Spectral-domain optical coherence tomography as an indicator of fluorescein angiography leakage from choroidal neovascularization.
Investigative ophthalmology & visual science Jul, 2011 | Pubmed ID: 21693602
Inhibitory effect of aminoimidazole carboxamide ribonucleotide (AICAR) on endotoxin-induced uveitis in rats.
Investigative ophthalmology & visual science Aug, 2011 | Pubmed ID: 21775660
An epigenetic approach toward understanding ocular α-herpesvirus pathogenesis and treatment.
International ophthalmology clinics , 2011 | Pubmed ID: 21897145
Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment.
PloS one , 2011 | Pubmed ID: 21961034
Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology.
PloS one , 2011 | Pubmed ID: 21998696
Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2012 | Pubmed ID: 22067481
Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration.
Human genomics Oct, 2011 | Pubmed ID: 22155603
Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse.
The American journal of pathology May, 2012 | Pubmed ID: 22429967
Aminoimidazole carboxamide ribonucleotide ameliorates experimental autoimmune uveitis.
Investigative ophthalmology & visual science , 2012 | Pubmed ID: 22562518
The regulatory roles of apoptosis-inducing factor in the formation and regression processes of ocular neovascularization.
The American journal of pathology Jul, 2012 | Pubmed ID: 22613025
Etanercept, a widely used inhibitor of tumor necrosis factor-α (TNF-α), prevents retinal ganglion cell loss in a rat model of glaucoma.
PloS one , 2012 | Pubmed ID: 22802951
Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2012 | Pubmed ID: 22908283
Vascular endothelial growth factor a in intraocular vascular disease.
Ophthalmology Jan, 2013 | Pubmed ID: 23031671
Age-related macular degeneration revisited--piecing the puzzle: the LXIX Edward Jackson memorial lecture.
American journal of ophthalmology Jan, 2013 | Pubmed ID: 23245386
Aminoimidazole carboxamide ribonucleotide (AICAR) inhibits the growth of retinoblastoma in vivo by decreasing angiogenesis and inducing apoptosis.
PloS one , 2013 | Pubmed ID: 23300996
Intravitreal injections at the Massachusetts Eye and Ear Infirmary: analysis of treatment indications and postinjection endophthalmitis rates.
The British journal of ophthalmology Apr, 2013 | Pubmed ID: 23390167
Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration.
American journal of ophthalmology Jul, 2013 | Pubmed ID: 23668679
AMP-dependent kinase inhibits oxidative stress-induced caveolin-1 phosphorylation and endocytosis by suppressing the dissociation between c-Abl and Prdx1 proteins in endothelial cells.
The Journal of biological chemistry Jul, 2013 | Pubmed ID: 23723070
Photoreceptor cell death and rescue in retinal detachment and degenerations.
Progress in retinal and eye research Aug, 2013 | Pubmed ID: 23994436
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