Maria Lerm

Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac.

Differential effects of invasion by and phagocytosis of Salmonella typhimurium on apoptosis in human macrophages: potential role of Rho-GTPases and Akt.

Inactivation of Cdc42 is necessary for depolymerization of phagosomal F-actin and subsequent phagosomal maturation.

Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: relation to common inflammatory diseases?

Incorporation of Mycobacterium tuberculosis lipoarabinomannan into macrophage membrane rafts is a prerequisite for the phagosomal maturation block.

Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis.

Leishmania donovani lipophosphoglycan inhibits phagosomal maturation via action on membrane rafts.

Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men.

Validation of a medium-throughput method for evaluation of intracellular growth of Mycobacterium tuberculosis.

Importance of phagosomal functionality for growth restriction of Mycobacterium tuberculosis in primary human macrophages.

Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis.

Inside or outside the phagosome? The controversy of the intracellular localization of Mycobacterium tuberculosis.

Common genetic variations in the NALP3 inflammasome are associated with delayed apoptosis of human neutrophils.

The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1β and IL-18 production.

Resistance to first-line anti-TB drugs is associated with reduced nitric oxide susceptibility in Mycobacterium tuberculosis.

TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation.

A mathematical model of the initial interaction between Mycobacterium tuberculosis and macrophages.

Human gene variants linked to enhanced NLRP3 activity limit intramacrophage growth of Mycobacterium tuberculosis.

Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue.

Apoptotic neutrophils augment the inflammatory response to Mycobacterium tuberculosis infection in human macrophages.

A luciferase-based assay for rapid assessment of drug activity against Mycobacterium tuberculosis including monitoring of macrophage viability.

Antimycobacterial activity of selected medicinal plants traditionally used in Sudan to treat infectious diseases.

Replication rates of Mycobacterium tuberculosis in human macrophages do not correlate with mycobacterial antibiotic susceptibility.

MicroRNA let-7 modulates the immune response to Mycobacterium tuberculosis infection via control of A20, an inhibitor of the NF-κB pathway.