Nathan Trinklein

Identification and functional analysis of human transcriptional promoters.

The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response.

An abundance of bidirectional promoters in the human genome.

Diverse and specific gene expression responses to stresses in cultured human cells.

Transcriptional regulation and binding of heat shock factor 1 and heat shock factor 2 to 32 human heat shock genes during thermal stress and differentiation.

Direct isolation and identification of promoters in the human genome.

Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome.

Serum response factor binding sites differ in three human cell types.

Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome.

Transcription factor binding and modified histones in human bidirectional promoters.

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

The ets-related transcription factor GABP directs bidirectional transcription.

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets.

A functional analysis of the CREB signaling pathway using HaloCHIP-chip and high throughput reporter assays.

Sequence features that drive human promoter function and tissue specificity.

Two-tiered approach identifies a network of cancer and liver disease-related genes regulated by miR-122.

Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.