Health Sciences and Technology,
Electrical Engineering and Computer Science and David H. Koch Institute for Integrative Cancer Research
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Microscale culture of human liver cells for drug development.
Nature biotechnology Jan, 2008 | Pubmed ID: 18026090
Combinatorial signaling microenvironments for studying stem cell fate.
Stem cells and development Feb, 2008 | Pubmed ID: 18271698
In vivo tumor cell targeting with "click" nanoparticles.
Bioconjugate chemistry Aug, 2008 | Pubmed ID: 18611045
T-cadherin modulates hepatocyte functions in vitro.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2008 | Pubmed ID: 18635739
Protease-triggered unveiling of bioactive nanoparticles.
Small (Weinheim an der Bergstrasse, Germany) Sep, 2008 | Pubmed ID: 18690639
Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug delivery.
Angewandte Chemie (International ed. in English) , 2008 | Pubmed ID: 18696519
The compatibility of hepatocytes with chemically modified porous silicon with reference to in vitro biosensors.
Biomaterials Jan, 2009 | Pubmed ID: 18845334
Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans.
Pediatric research Jan, 2009 | Pubmed ID: 18852689
Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers.
Biomaterials Feb, 2009 | Pubmed ID: 19046762
Statistical dynamics of flowing red blood cells by morphological image processing.
PLoS computational biology Feb, 2009 | Pubmed ID: 19214200
Biodegradable luminescent porous silicon nanoparticles for in vivo applications.
Nature materials Apr, 2009 | Pubmed ID: 19234444
Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting.
Small (Weinheim an der Bergstrasse, Germany) Mar, 2009 | Pubmed ID: 19263431
Computationally guided photothermal tumor therapy using long-circulating gold nanorod antennas.
Cancer research May, 2009 | Pubmed ID: 19366797
Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance.
Biomaterials Aug, 2009 | Pubmed ID: 19394687
Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro.
Hepatology (Baltimore, Md.) Sep, 2009 | Pubmed ID: 19585615
Functional delivery of siRNA in mice using dendriworms.
ACS nano Sep, 2009 | Pubmed ID: 19673534
Urinary tract infection in a healthy 10-year-old boy: an occult etiology.
Pediatric emergency care Sep, 2009 | Pubmed ID: 19755897
Tissue-specific gene delivery via nanoparticle coating.
Biomaterials Feb, 2010 | Pubmed ID: 19850333
Silicon nanoparticles as hyperpolarized magnetic resonance imaging agents.
ACS nano Dec, 2009 | Pubmed ID: 19950973
Cooperative nanomaterial system to sensitize, target, and treat tumors.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2010 | Pubmed ID: 20080556
丙型肝炎病毒感染使用荧光基于单元格的记者系统的实时图像。
Nature biotechnology Feb, 2010 | Pubmed ID: 20118917
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2010 | Pubmed ID: 20133632
The pipeline still leaks and more than you think: a status report on gender diversity in biomedical engineering.
Annals of biomedical engineering May, 2010 | Pubmed ID: 20162356
SERS-Coded Gold Nanorods as a Multifunctional Platform for Densely Multiplexed Near-Infrared Imaging and Photothermal Heating.
Advanced materials (Deerfield Beach, Fla.) Apr, 2009 | Pubmed ID: 20174478
Cooperative nanoparticles for tumor detection and photothermally triggered drug delivery.
Advanced materials (Deerfield Beach, Fla.) Feb, 2010 | Pubmed ID: 20217810
Targeting of drugs and nanoparticles to tumors.
The Journal of cell biology Mar, 2010 | Pubmed ID: 20231381
Effect of nanoparticle conjugation on gene silencing by RNA interference.
Journal of the American Chemical Society Jun, 2010 | Pubmed ID: 20518524
Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics.
Integrative biology : quantitative biosciences from nano to macro Jun, 2010 | Pubmed ID: 20532320
Single cell trapping and DNA damage analysis using microwell arrays.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20534572
Ligand-clustered "patchy" nanoparticles for modulated cellular uptake and in vivo tumor targeting.
Angewandte Chemie (International ed. in English) Sep, 2010 | Pubmed ID: 20740515
Multiplexed, high-throughput analysis of 3D microtissue suspensions.
Integrative biology : quantitative biosciences from nano to macro Oct, 2010 | Pubmed ID: 20820630
Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2011 | Pubmed ID: 21187397
In-silico patterning of vascular mesenchymal cells in three dimensions.
PloS one , 2011 | Pubmed ID: 21633504
Using C. elegans to identify the protease targets of serpins in vivo.
Methods in enzymology , 2011 | Pubmed ID: 21683259
Nanoparticles that communicate in vivo to amplify tumour targeting.
Nature materials Jul, 2011 | Pubmed ID: 21685903
Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging.
Advanced materials (Deerfield Beach, Fla.) May, 2008 | Pubmed ID: 21687830
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2011 | Pubmed ID: 21746896
Humanized mice with ectopic artificial liver tissues.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2011 | Pubmed ID: 21746904
DNA-templated assembly of droplet-derived PEG microtissues.
Lab on a chip Sep, 2011 | Pubmed ID: 21776518
Bioresponsive mesoporous silica nanoparticles for triggered drug release.
Journal of the American Chemical Society Dec, 2011 | Pubmed ID: 21981330
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells.
Hepatology (Baltimore, Md.) Dec, 2011 | Pubmed ID: 22144107
Modeling hepatitis C virus infection using human induced pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308485
A biophysical indicator of vaso-occlusive risk in sickle cell disease.
Science translational medicine Feb, 2012 | Pubmed ID: 22378926
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues.
Nature materials Jul, 2012 | Pubmed ID: 22751181
The challenges posed by cancer heterogeneity.
Nature biotechnology Jul, 2012 | Pubmed ID: 22781679
Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4.
Science translational medicine Aug, 2012 | Pubmed ID: 22896676
Cancer vulnerabilities unveiled by genomic loss.
Cell Aug, 2012 | Pubmed ID: 22901813
Identification and characterization of receptor-specific peptides for siRNA delivery.
ACS nano Oct, 2012 | Pubmed ID: 22909216
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2012 | Pubmed ID: 23033492
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis.
Nature communications , 2012 | Pubmed ID: 23047680
Bioengineering methods for analysis of cells in vitro.
Annual review of cell and developmental biology , 2012 | Pubmed ID: 23057744
Genetic Circuits in Salmonella typhimurium.
ACS synthetic biology Oct, 2012 | Pubmed ID: 23097749
In Vivo Gene Expression Dynamics of Tumor-Targeted Bacteria.
ACS synthetic biology Oct, 2012 | Pubmed ID: 23097750
What is the greatest regulatory challenge in the translation of biomaterials to the clinic?
Science translational medicine Nov, 2012 | Pubmed ID: 23152323
Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease.
Nature biotechnology Jan, 2013 | Pubmed ID: 23242163
Flow-based pipeline for systematic modulation and analysis of 3D tumor microenvironments.
Lab on a chip May, 2013 | Pubmed ID: 23563587
Geometric control of vascular networks to enhance engineered tissue integration and function.
Proceedings of the National Academy of Sciences of the United States of America May, 2013 | Pubmed ID: 23610423
Mitochondrial localization and the persistent migration of epithelial cancer cells.
Biophysical journal May, 2013 | Pubmed ID: 23663851
Identification of small molecules for human hepatocyte expansion and iPS differentiation.
Nature chemical biology Jun, 2013 | Pubmed ID: 23728495
1Health Sciences and Technology, Massachusetts Institute of Technology,
2Department of Bioengineering, University of California, San Diego ,
3Biocircuits Institute, University of California, San Diego ,
4Molecular Biology Section, Division of Biological Science, University of California, San Diego ,
5, Broad Institute of Harvard and MIT,
6Department of Medicine, Brigham and Women's Hospital,
7Electrical Engineering and Computer Science and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology,
8, Howard Hughes Medical Institute
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