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Phenotyping transgenic embryos: a rapid 3-D screening method based on episcopic fluorescence image capturing.
Nature genetics Jan, 2002 | Pubmed ID: 11743576
Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice.
Blood Jan, 2002 | Pubmed ID: 11781236
Folic acid prevents exencephaly in Cited2 deficient mice.
Human molecular genetics Feb, 2002 | Pubmed ID: 11823447
Migration and differentiation of CD8+ T cells.
Immunological reviews Aug, 2002 | Pubmed ID: 12234374
Naive T cell recruitment to nonlymphoid tissues: a role for endothelium-expressed CC chemokine ligand 21 in autoimmune disease and lymphoid neogenesis.
Journal of immunology (Baltimore, Md. : 1950) May, 2003 | Pubmed ID: 12707342
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells.
Nature Jul, 2003 | Pubmed ID: 12840763
Visualizing T cell migration in vivo.
International archives of allergy and immunology Dec, 2003 | Pubmed ID: 14707460
Sheet preparations expose the dermal nerve plexus of human skin and render the dermal nerve end organ accessible to extensive analysis.
The Journal of investigative dermatology Jan, 2004 | Pubmed ID: 14962106
In vivo 3D analysis of the adipose tissue in the orbital apex and the compartments of the parasellar region.
Clinical anatomy (New York, N.Y.) Mar, 2004 | Pubmed ID: 14974098
Chemokine regulation of naïve T cell traffic in health and disease.
Seminars in immunology Oct, 2003 | Pubmed ID: 15001175
CXCL12 mediates CCR7-independent homing of central memory cells, but not naive T cells, in peripheral lymph nodes.
The Journal of experimental medicine Apr, 2004 | Pubmed ID: 15096537
Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells.
Immunity Feb, 2005 | Pubmed ID: 15723813
Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development.
Development (Cambridge, England) Mar, 2005 | Pubmed ID: 15750185
Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells.
Nature immunology Oct, 2005 | Pubmed ID: 16155571
Dendritic cell maturation, but not CD8+ T cell induction, is dependent on type I IFN signaling during vaccination with adenovirus vectors.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2005 | Pubmed ID: 16237098
From experimental imaging techniques to virtual embryology.
History and philosophy of the life sciences , 2004 | Pubmed ID: 16302693
High-resolution episcopic microscopy: a rapid technique for high detailed 3D analysis of gene activity in the context of tissue architecture and morphology.
Anatomy and embryology Jun, 2006 | Pubmed ID: 16429276
Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation.
Immunity Jul, 2006 | Pubmed ID: 16860762
Immune cell migration as a means to control immune privilege: lessons from the CNS and tumors.
Immunological reviews Oct, 2006 | Pubmed ID: 16972905
CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1.
The Journal of cell biology Nov, 2006 | Pubmed ID: 17101694
Random migration precedes stable target cell interactions of tumor-infiltrating T cells.
The Journal of experimental medicine Nov, 2006 | Pubmed ID: 17116735
Asymmetric T lymphocyte division in the initiation of adaptive immune responses.
Science (New York, N.Y.) Mar, 2007 | Pubmed ID: 17332376
microMRI-HREM pipeline for high-throughput, high-resolution phenotyping of murine embryos.
Journal of anatomy Jul, 2007 | Pubmed ID: 17532797
Negative regulation of TLR-signaling pathways by activating transcription factor-3.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2007 | Pubmed ID: 17785797
Two distinct activation states of plasmacytoid dendritic cells induced by influenza virus and CpG 1826 oligonucleotide.
Journal of leukocyte biology Mar, 2008 | Pubmed ID: 18029397
Two-photon imaging of effector T-cell behavior: lessons from a tumor model.
Immunological reviews Feb, 2008 | Pubmed ID: 18275480
Three-dimensional analysis of molecular signals with episcopic imaging techniques.
Methods in molecular biology (Clifton, N.J.) , 2007 | Pubmed ID: 18287637
Three-dimensional description and mathematical characterization of the parasellar internal carotid artery in human infants.
Journal of anatomy May, 2008 | Pubmed ID: 18397239
Fibroblast migration is mediated by CD44-dependent TGF beta activation.
Journal of cell science May, 2008 | Pubmed ID: 18397995
Dendritic cell behaviour in vivo: lessons learned from intravital two-photon microscopy.
Immunology and cell biology Jul, 2008 | Pubmed ID: 18431356
Objective characterization of the course of the parasellar internal carotid artery using mathematical tools.
Surgical and radiologic anatomy : SRA Aug, 2008 | Pubmed ID: 18523720
Transforming growth factor-beta receptor blockade augments the effectiveness of adoptive T-cell therapy of established solid cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2008 | Pubmed ID: 18559619
Visualizing dendritic cell migration within the skin.
Histochemistry and cell biology Dec, 2008 | Pubmed ID: 18987873
Migratory dermal dendritic cells act as rapid sensors of protozoan parasites.
PLoS pathogens Nov, 2008 | Pubmed ID: 19043558
CD44 mediates successful interstitial navigation by killer T cells and enables efficient antitumor immunity.
Immunity Dec, 2008 | Pubmed ID: 19100702
Plasmacytoid dendritic cells are dispensable during primary influenza virus infection.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2009 | Pubmed ID: 19124730
Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesis-associated system of reticular fibers.
Immunity Feb, 2009 | Pubmed ID: 19167248
In vivo imaging of cutaneous T-cell lymphoma migration to the skin.
Cancer research Apr, 2009 | Pubmed ID: 19318575
Episcopic 3D Imaging Methods: Tools for Researching Gene Function.
Current genomics Jun, 2008 | Pubmed ID: 19452045
Distribution and three-dimensional appearance of the interstitial cells of Cajal in the rat stomach and duodenum.
Microscopy research and technique Dec, 2009 | Pubmed ID: 19455682
Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii.
PLoS pathogens Jul, 2009 | Pubmed ID: 19578440
Matrix crosslinking forces tumor progression by enhancing integrin signaling.
Cell Nov, 2009 | Pubmed ID: 19931152
Visualizing vertebrate embryos with episcopic 3D imaging techniques.
TheScientificWorldJournal , 2009 | Pubmed ID: 20024516
Trafficking of immune cells in the central nervous system.
The Journal of clinical investigation May, 2010 | Pubmed ID: 20440079
Herpes simplex virus infects skin gamma delta T cells before Langerhans cells and impedes migration of infected Langerhans cells by inducing apoptosis and blocking E-cadherin downregulation.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2010 | Pubmed ID: 20519652
Bone marrow chimeric mice reveal a role for CX₃CR1 in maintenance of the monocyte-derived cell population in the olfactory neuroepithelium.
Journal of leukocyte biology Oct, 2010 | Pubmed ID: 20610801
Cell-autonomous and environmental contributions to the interstitial migration of T cells.
Seminars in immunopathology Sep, 2010 | Pubmed ID: 20623124
Advances in imaging the innate and adaptive immune response to Toxoplasma gondii.
Future microbiology Sep, 2010 | Pubmed ID: 20860479
How nickel turns on innate immune cells.
Immunology and cell biology Jan, 2011 | Pubmed ID: 20938456
Targeted induction of antigen expression within dendritic cells modulates antigen-specific immunity afforded by recombinant BCG.
Vaccine Feb, 2011 | Pubmed ID: 21211591
Cutaneous immunosurveillance by self-renewing dermal gammadelta T cells.
The Journal of experimental medicine Mar, 2011 | Pubmed ID: 21339323
Active immunotherapy combined with blockade of a coinhibitory pathway achieves regression of large tumor masses in cancer-prone mice.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2011 | Pubmed ID: 21587210
Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events.
The Journal of investigative dermatology Oct, 2011 | Pubmed ID: 21697893
Imaging heart development using high-resolution episcopic microscopy.
Current opinion in genetics & development Oct, 2011 | Pubmed ID: 21893408
Analysis of behavior and trafficking of dendritic cells within the brain during toxoplasmic encephalitis.
PLoS pathogens Sep, 2011 | Pubmed ID: 21949652
High-resolution episcopic microscopy data-based measurements of the arteries of mouse embryos: evaluation of significance and reproducibility under routine conditions.
Cells, tissues, organs , 2012 | Pubmed ID: 21997436
Langerhans cells are precommitted to immune tolerance induction.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2011 | Pubmed ID: 22006331
Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots.
Nature immunology Jan, 2012 | Pubmed ID: 22138716
Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.
Clinical cancer research : an official journal of the American Association for Cancer Research Feb, 2012 | Pubmed ID: 22173547
Phenotype and functions of conventional dendritic cells are not compromised in aged mice.
Immunology and cell biology Aug, 2012 | Pubmed ID: 22231652
Intravital multiphoton imaging of immune responses in the mouse ear skin.
Nature protocols Feb, 2012 | Pubmed ID: 22240584
Some mice feature 5th pharyngeal arch arteries and double-lumen aortic arch malformations.
Cells, tissues, organs , 2012 | Pubmed ID: 22287557
A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8⁺ T-cell accumulation in the skin.
The Journal of investigative dermatology Jul, 2012 | Pubmed ID: 22297636
Episcopic three-dimensional imaging of embryos.
Cold Spring Harbor protocols Jun, 2012 | Pubmed ID: 22661435
Embedding embryos for episcopic fluorescence image capturing (EFIC).
Cold Spring Harbor protocols Jun, 2012 | Pubmed ID: 22661436
Embedding embryos for high-resolution episcopic microscopy (HREM).
Cold Spring Harbor protocols Jun, 2012 | Pubmed ID: 22661437
Generation of volume data by episcopic three-dimensional imaging of embryos.
Cold Spring Harbor protocols Jun, 2012 | Pubmed ID: 22661438
Models in researching cardiovascular morphogenesis.
Birth defects research. Part C, Embryo today : reviews Jun, 2012 | Pubmed ID: 22692889
Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells.
Nature Jun, 2012 | Pubmed ID: 22722867
Inflammasome-dependent IFN-γ drives pathogenesis in Streptococcus pneumoniae meningitis.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2012 | Pubmed ID: 23071286
Metric characterization of the aortic arch of early mouse fetuses and of a fetus featuring a double lumen aortic arch malformation.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft Mar, 2013 | Pubmed ID: 23123185
Western lifestyle and increased prevalence of atopic diseases: an example from a small papua new guinean island.
The World Allergy Organization journal Jul, 2009 | Pubmed ID: 23283062
Visualizing leukocyte trafficking in the living brain with 2-photon intravital microscopy.
Frontiers in cellular neuroscience , 2012 | Pubmed ID: 23316136
Shedding light on cutaneous innate immune responses: the intravital microscopy approach.
Immunology and cell biology Apr, 2013 | Pubmed ID: 23459295
Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice.
Disease models & mechanisms May, 2013 | Pubmed ID: 23519034
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.
Nature immunology Apr, 2013 | Pubmed ID: 23603794
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells.
Cancer research Aug, 2013 | Pubmed ID: 23946473
Mesenchymal cells hold the key to immune cell recruitment to and migration within melanoma.
The Journal of investigative dermatology Sep, 2013 | Pubmed ID: 23949769
A coming of age: advanced imaging technologies for characterising the developing mouse.
Trends in genetics : TIG Dec, 2013 | Pubmed ID: 24035368
Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection.
Nature immunology Jan, 2014 | Pubmed ID: 24270515
A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction.
Cell Feb, 2014 | Pubmed ID: 24529375
Targeting Rho-GTPases in immune cell migration and inflammation.
British journal of pharmacology Dec, 2014 | Pubmed ID: 24571448
The Skin-Resident Immune Network.
Current dermatology reports , 2014 | Pubmed ID: 24587975
Leukocyte migration in the interstitial space of non-lymphoid organs.
Nature reviews. Immunology Apr, 2014 | Pubmed ID: 24603165
Anatomical and ultrasound correlation of the superficial branch of the radial nerve.
Muscle & nerve Dec, 2014 | Pubmed ID: 24604158
Real-time cell cycle imaging during melanoma growth, invasion, and drug response.
Pigment cell & melanoma research Sep, 2014 | Pubmed ID: 24902993
T cell migration in intact lymph nodes in vivo.
Current opinion in cell biology Oct, 2014 | Pubmed ID: 24907445
Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2014 | Pubmed ID: 24927525
Monocyte homeostasis and the plasticity of inflammatory monocytes.
Cellular immunology Sep-Oct, 2014 | Pubmed ID: 24962351
The skin immune atlas: three-dimensional analysis of cutaneous leukocyte subsets by multiphoton microscopy.
The Journal of investigative dermatology Jan, 2015 | Pubmed ID: 25007044
Real-time imaging reveals the dynamics of leukocyte behaviour during experimental cerebral malaria pathogenesis.
PLoS pathogens Jul, 2014 | Pubmed ID: 25033406
CD326(lo)CD103(lo)CD11b(lo) dermal dendritic cells are activated by thymic stromal lymphopoietin during contact sensitization in mice.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2014 | Pubmed ID: 25057004
Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2014 | Pubmed ID: 25070847
High-resolution episcopic microscopy (HREM): a tool for visualizing skin biopsies.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada Oct, 2014 | Pubmed ID: 25198556
Phenotyping structural abnormalities in mouse embryos using high-resolution episcopic microscopy.
Disease models & mechanisms Oct, 2014 | Pubmed ID: 25256713
Ultrasound and anatomical correlation of the radial nerve at the arcade of Frohse.
Muscle & nerve Jun, 2015 | Pubmed ID: 25297493
Simultaneous dermal matrix and autologous split-thickness skin graft transplantation in a porcine wound model: a three-dimensional histological analysis of revascularization.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society Nov-Dec, 2014 | Pubmed ID: 25358670
Dual modality optical coherence and whole-body photoacoustic tomography imaging of chick embryos in multiple development stages.
Biomedical optics express Sep, 2014 | Pubmed ID: 25401028
Real-time imaging of dendritic cell responses to sterile tissue injury.
The Journal of investigative dermatology Apr, 2015 | Pubmed ID: 25431854
Dermal group 2 innate lymphoid cells in atopic dermatitis and allergy.
Current opinion in immunology Dec, 2014 | Pubmed ID: 25459002
High-resolution episcopic microscopy (HREM): a useful technique for research in wound care.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft Jan, 2015 | Pubmed ID: 25466930
Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling.
Immunity Dec, 2014 | Pubmed ID: 25526309
Imaging the zebrafish dentition: from traditional approaches to emerging technologies.
Zebrafish Feb, 2015 | Pubmed ID: 25560992
Group 2 innate lymphoid cells in the regulation of immune responses.
Advances in immunology , 2015 | Pubmed ID: 25591466
IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria.
Infection and immunity Apr, 2015 | Pubmed ID: 25644000
Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation.
Nature communications , 2015 | Pubmed ID: 25709008
The role of chemokines in cutaneous immunosurveillance.
Immunology and cell biology Apr, 2015 | Pubmed ID: 25776847
ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms.
Nature communications , 2015 | Pubmed ID: 25912172
Ultrasound-Guided Perineural Injection at Guyon's Tunnel: An Anatomic Feasibility Study.
Ultrasound in medicine & biology Aug, 2015 | Pubmed ID: 25937521
IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation.
The Journal of allergy and clinical immunology Dec, 2015 | Pubmed ID: 26025126
Shedding light on cell cycle control by T and B lymphocytes.
Cell cycle (Georgetown, Tex.) Aug, 2015 | Pubmed ID: 26133027
The dynamic anatomy and patterning of skin.
Experimental dermatology Aug, 2015 | Pubmed ID: 26284579
Longitudinal Gliding of the Median Nerve in the Carpal Tunnel: Ultrasound Cadaveric Evaluation of Conventional and Novel Concepts of Nerve Mobilization.
Archives of physical medicine and rehabilitation Dec, 2015 | Pubmed ID: 26315068
Apolipoprotein A-I Limits the Negative Effect of Tumor Necrosis Factor on Lymphangiogenesis.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2015 | Pubmed ID: 26359513
Neutrophils Self-Regulate Immune Complex-Mediated Cutaneous Inflammation Through CXCL2.
The Journal of investigative dermatology Oct, 2015 | Pubmed ID: 26480280
Chi Ching Goh1,2,
Jackson LiangYao Li1,
David Becker3,
Wolfgang Weninger4,5,6,
Veronique Angeli2,7,
Lai Guan Ng1,2,5,8
1Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis,
2Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore,
3Lee Kong Chian School of Medicine, Nanyang Technological University,
4, Centenary Institute for Cancer Medicine and Cell Biology,
5Discipline of Dermatology, University of Sydney,
6Department of Dermatology, Royal Prince Alfred Hospital,
7LSI Immunology Programme, National University of Singapore,
8School of Biological Sciences, Nanyang Technological University
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