Xiaomin Zhang

In vivo bioluminescence imaging of transplanted islets and early detection of graft rejection.

Polymer scaffolds as synthetic microenvironments for extrahepatic islet transplantation.

The epididymal fat pad as a transplant site for minimal islet mass.

Prolonging islet allograft survival using in vivo bioluminescence imaging to guide timing of antilymphocyte serum treatment of rejection.

Extracellular matrix protein-coated scaffolds promote the reversal of diabetes after extrahepatic islet transplantation.

ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms.

Comparative study of regenerative potential of beta cells from young and aged donor mice using a novel islet transplantation model.

In vivo detection of extrapancreatic insulin gene expression in diabetic mice by bioluminescence imaging.

Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.

Protein polymer MRI contrast agents: Longitudinal analysis of biomaterials in vivo.

Permanent protection of PLG scaffold transplanted allogeneic islet grafts in diabetic mice treated with ECDI-fixed donor splenocyte infusions.

Extrahepatic islet transplantation with microporous polymer scaffolds in syngeneic mouse and allogeneic porcine models.

Conditional and specific inhibition of NF-κB in mouse pancreatic β cells prevents cytokine-induced deleterious effects and improves islet survival posttransplant.

Porous scaffolds support extrahepatic human islet transplantation, engraftment, and function in mice.

Protein polymer hydrogels: effects of endotoxin on biocompatibility.

PLG scaffold delivered antigen-specific regulatory T cells induce systemic tolerance in autoimmune diabetes.

Accumulation of cadmium in insulin-producing β cells.

Collagen IV-modified scaffolds improve islet survival and function and reduce time to euglycemia.

Transient B-cell depletion combined with apoptotic donor splenocytes induces xeno-specific T- and B-cell tolerance to islet xenografts.

Knockdown of intraislet IKKβ by spherical nucleic acid conjugates prevents cytokine-induced injury and enhances graft survival.

Preemptive Tolerogenic Delivery of Donor Antigens for Permanent Allogeneic Islet Graft Protection.

Nanoparticle delivery of donor antigens for transplant tolerance in allogeneic islet transplantation.

Transforming growth factor-beta 1 delivery from microporous scaffolds decreases inflammation post-implant and enhances function of transplanted islets.

Mold-casted non-degradable, islet macro-encapsulating hydrogel devices for restoration of normoglycemia in diabetic mice.

National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities.

Differential Role of B Cells and IL-17 Versus IFN-γ During Early and Late Rejection of Pig Islet Xenografts in Mice.

Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel.

Murine CMV induces type 1 IFN that impairs differentiation of MDSCs critical for transplantation tolerance.

Evaluation of biomaterial scaffold delivery of IL-33 as a localized immunomodulatory agent to support cell transplantation in adipose tissue.

Receptor tyrosine kinase MerTK suppresses an allogenic type I IFN response to promote transplant tolerance.

An elastin-based vasculogenic scaffold promotes marginal islet mass engraftment and function at an extrahepatic site.