Elaine Dzierzak

Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity.

Expression of the Ly-6A (Sca-1) lacZ transgene in mouse haematopoietic stem cells and embryos.

Ontogeny and genetics of the hemato/lymphopoietic system.

Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis.

Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo.

Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta.

Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation.

Hematopoietic stem cells and their precursors: developmental diversity and lineage relationships.

Comparative study of stromal cell lines derived from embryonic, fetal, and postnatal mouse blood-forming tissues.

Identification of 2 novel genes developmentally regulated in the mouse aorta-gonad-mesonephros region.

The Ly-6A (Sca-1) GFP transgene is expressed in all adult mouse hematopoietic stem cells.

Impaired hematopoiesis in mice lacking the transcription factor Sp3.

Ontogenic emergence of definitive hematopoietic stem cells.

The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression.

Cell-cell contact and anatomical compatibility in stromal cell-mediated HSC support during development.

Generation of murine stromal cell lines: models for the microenvironment of the embryonic mouse aorta-gonads-mesonephros region.

GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells.

Hematopoietic stem cell enrichment from the AGM region of the mouse embryo.

Embryonic beginnings of adult hematopoietic stem cells.

Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny.

The murine placenta contains hematopoietic stem cells within the vascular labyrinth region.

The emergence of definitive hematopoietic stem cells in the mammal.

Sca-1 negatively regulates proliferation and differentiation of muscle cells.

Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures.

Multipotential hematopoietic progenitor cells from embryos developed in vitro engraft unconditioned W41/W41 neonatal miceB.

An unexpected role for IL-3 in the embryonic development of hematopoietic stem cells.

Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells.

Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad-mesonephros microenvironment.

Mesenchymal lineage potentials of aorta-gonad-mesonephros stromal clones.

Bcl-2 expression and apoptosis in the regulation of hematopoietic stem cells.

Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells.

Of lineage and legacy: the development of mammalian hematopoietic stem cells.

Stem cell researchers find their niche.

Fine-tuning of hematopoietic stem cell homeostasis: novel role for ubiquitin ligase.

Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.

The discovery of a source of adult hematopoietic cells in the embryo.

Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.

Analysis and manipulation of hematopoietic progenitor and stem cells from murine embryonic tissues.

Interleukin-1-mediated hematopoietic cell regulation in the aorta-gonad-mesonephros region of the mouse embryo.

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter.

Interleukin-1 regulates hematopoietic progenitor and stem cells in the midgestation mouse fetal liver.

Analysis of the mouse placenta as a hematopoietic stem cell niche.

Hematopoietic stem cell development is dependent on blood flow.

Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development.

Opening act in a hematopoietic program.

Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling.

Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development.

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium.

Placenta as a source of hematopoietic stem cells.

The placenta as a haematopoietic organ.

Preparation of hematopoietic stem and progenitor cells from the human placenta.

Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos.

Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.

Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line.

The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization.

CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells.

Isolation and analysis of hematopoietic stem cells from mouse embryos.

Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters.

A Role for PML in Innate Immunity.

Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells.

Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos.