Okinawa Institute of Science and Technology

2 ARTICLES PUBLISHED IN JoVE

Neuroscience

C. elegans Tracking and Behavioral Measurement

Jirapat Likitlersuang¹, Greg Stephens^2,3, Konstantine Palanski¹, William S. Ryu^1,4

¹Donnelly Centre, University of Toronto, ²Department of Physics and Astronomy, Vrije Universiteit, ³Okinawa Institute of Science and Technology, ⁴Department of Physics, University of Toronto

We have developed a video-rate tracking microscope system that can record and quantify C. elegans behavior at high resolution and high speeds. We have also developed computational methods to reduce the dimensionality of the worm images to a fundamental set of measurements that completely describe the shape of the worm.

Behavior

New Variations for Strategy Set-shifting in the Rat

Sho Aoki¹, Andrew W. Liu¹, Aya Zucca¹, Stefano Zucca¹, Jeffery R. Wickens¹

¹Neurobiology Research Unit, Okinawa Institute of Science and Technology

Set-shifting, a form of behavioral flexibility, requires an attentional shift from one stimulus dimension to another. We extended an established rodent set-shifting task¹ by requiring attention to different stimuli according to context. The task was combined with specific lesions to identify neuron subtypes underlying a successful shift.