Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical AerosolsXiuhua A. Si 1, Jinxiang Xi 2
1Department of Mechanical Engineering, California Baptist University, 2School of Engineering and Technology, Central Michigan University
This manuscript reviews the modeling and simulations of different protocols to deliver medications to the olfactory region in image-based nasal airway models. Multiple software modules are used to develop the anatomically accurate nose model, generate computational mesh, simulate nasal airflows, and predict particle deposition at the olfactory region.
