An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited SettingsJusten Manasa 1, Siva Danaviah 1, Sureshnee Pillay 1, Prevashinee Padayachee 1, Hloniphile Mthiyane 1, Charity Mkhize 1, Richard John Lessells 1, Christopher Seebregts 2, Tobias F. Rinke de Wit 3, Johannes Viljoen 1, David Katzenstein 4, Tulio De Oliveira 1
1Africa Centre for Health and Population Studies, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa, 2Unit D11, Jembi Health Systems, 3Academic Medical Center, Department of Global Health, Amsterdam Institute for Global Health and Development (AIGHD), University of Amsterdam, 4Division of Infectious Diseases and Geographic Medicine, Centre for AIDS Research, Stanford Medical School
Drug resistance testing for HIV-1 infected individuals failing antiretroviral therapy (ART) can guide future therapies and improve treatment outcomes. Optimizing individual and population health outcomes in high HIV prevalence but resource-limited settings will ultimately require affordable and accessible drug resistance genotyping and interpretation methods.
