Current Strategies for Controlling Dengue/Malaria Transmission
2:30
Population Replacement Strategy
4:29
Effector Genes and Mosquito Physiology
6:18
Gene Drive Systems
7:54
Design Criteria for Gene Drive Systems
10:50
Conditions that Must be Met before Implementing Population Replacem
12:28
Ethical Consideratons Regarding the Release of Genetically-Modified
13:31
1. Host Country`s Regulatory Infrastructure
13:31
2. Community Consent
16:57
3. Participation of Individuals at Field Sites
17:35
End Credits
In this candid interview, Anthony A. James explains how mosquito genetics can be exploited to control malaria and dengue transmission. Population replacement strategy, the idea that transgenic mosquitoes can be released into the wild to control disease transmission, is introduced as well as the concept of genetic drive and the design criterion for an effective genetic drive system. The ethical considerations of releasing genetically-modified organisms into the wild are also discussed.
