Prepare Protein-only Amyloid Directly from Native Proteins
2:06
Prepare Hybrid Amyloid from Stabilized Soluble Oligomers of Native Proteins
4:01
Results: Analysis of the Amyloid and Soluble Protein Oligomer
5:25
Conclusion
Proteins can either adopt a native structure or misfold into insoluble amyloid. Conditions that favor the misfolding pathway lead to the formation of different types of amyloid fibrils. The methods described here allow rapid conversion of native proteins into amyloid in vitro.
