The overall goal of this animal model is to establish group B Streptococcus, or GBS colonization of the murine vaginal tract. This method can help us understand key questions about group B Streptococcal colonization, such as, what are the bacteria
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The purpose of this protocol is to imitate human group B Streptococcus (GBS) vaginal colonization in a murine model. This method may be used to investigate host immune responses and bacterial factors contributing to GBS vaginal persistence, as well as to test therapeutic strategies.
