Set Up and Pre-experimental Acclimation Phase - Days 1 and 2
3:13
Experimental Baseline Phase - Days 3 to 9
5:23
Experimental Restriction Phase - Days 11 to 23
6:39
Results: Assessing Biochemical Consequences of Activity-based Anorexia
7:44
Conclusion
副本
The overall goal of this experiment is to examine the neurobiology and behavior underlying anorexia nervosa. This method can help answer key questions in the field of psychiatry related to eating disorders such as what are the neural underpinnings
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Mice individually housed with a running wheel while given limited access to food develop reductions in food consumption and increase activity on the running wheel. This experimental phenomenon is called activity-based anorexia. This paradigm provides an experimental tool for studying the neurobiology and behaviors underlying aspects of anorexia nervosa.
