Electrochemical biosensors detect the binding of a target molecule by sensing an oxidation-reduction event. These sensors paved the way for modern biosensing after the invention of the glucose biosensor. This video will introduce electrochemical biosensing, show the workings of the glucose biosensor, and discuss how electrochemical biosensors are used in cancer detection.
Electrochemical biosensors exploit the natural redox properties of many biological processes, such as enzyme catalysis and other binding events. Electrochemical sensors utilize electrodes which are often functionalized with redox active enzymes. When the target molecule is involved in a reaction with the enzyme the gain or loss of electrons is measured and related to concentration. In this video, we will review the principles of electrochemical sensing then describe the basics of an example electroche
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