This simple and effective muscle-gap separation model technique combine the ways of mini-invasion method is the best internal fixation in our rat knee joint contraction model. The main advantage of this technique is that it's process are reproduci
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Here, we present a protocol to describe a minimally invasive technique for knee joint immobilization in a rat model. This reproducible protocol, basing on muscle-gap separation modus and the mini-incision skill, is suitable for studying the underlying molecular mechanism of acquired joint contracture.