Our idea for the reaction site validation of MOF-based catalyst gives reliable data about whether a reaction takes place on the inner or outer surface of MOFs. These methods can be used to evaluate reaction sites, which can be crucial in the desig
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Here, we present a protocol for active site validation of metal-organic framework catalysts by comparing stoichiometric and catalytic carbonyl-ene reactions to find out whether a reaction takes place on the inner or outer surface of metal-organic frameworks.