Preparation of Reagents and Supplies and Cage Setup
3:15
Levodopa-Induced Dyskinesia Rating Post-Injection
4:04
Results: L-DOPA-Induced Dyskinesias (LID) Assessment in the Parkinsonian Rats
5:06
Conclusion
副本
Our protocol provides a detailed method for a reliable induction and comprehensive rating of levodopa-induced dyskinesia in a rat model of Parkinson's disease. The main advantage of our dyskinesia rating scale is that it allows for quantification
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This article describes methods to induce and evaluate levodopa-induced dyskinesias in a rat model of Parkinson's disease. The protocol offers detailed information regarding the intensity and frequency of a range of dyskinetic behaviors, both dystonic and hyperkinetic, providing a reliable tool to test treatments targeting this unmet medical need.
