Results: Detecting the Lysis of Plasmodium and its Parasitophorous Vacuole in Host Hepatocytes
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Conclusion
副本
Currently we have a limited understanding of the biology of plasmodium infection of the liver. This protocol has helped us generate a lot of transgenic lines that has helped answer some critical questions about the biology of the organism. A funda
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Malaria is transmitted through inoculation of the sporozoite stage of Plasmodium by infected mosquitoes. Transgenic Plasmodium has allowed us to understand the biology of malaria better and has contributed directly to malaria vaccine development efforts. Here, we describe a streamlined methodology to generate transgenic Plasmodium berghei sporozoites.
