<meta charset="utf8"></head><body>中医耳尖疗法治疗 COPD 患者喘息

<ol>
	<li>Bagdonas, E., Raudoniute, J., Bruzauskaite, I., Aldonyte, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Novel+aspects+of+pathogenesis+and+regeneration+mechanisms+in+COPD.">Novel aspects of pathogenesis and regeneration mechanisms in COPD.</a> Int J Chron Obstruct Pulmon Dis. 10, 995-1013 (2015).</li><li>Chai, X., Chen, Y., Li, Y., Chi, J., Guo, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Lower+geriatric+nutritional+risk+index+is+associated+with+a+higher+risk+of+all-cause+mortality+in+patients+with+chronic+obstructive+pulmonary+disease:+a+cohort+study+from+the+National+Health+and+Nutrition+Examination+Survey+2013-2018.">Lower geriatric nutritional risk index is associated with a higher risk of all-cause mortality in patients with chronic obstructive pulmonary disease: a cohort study from the National Health and Nutrition Examination Survey 2013-2018.</a> BMJ Open Respir Res. 10 (1), e001518 (2023).</li><li>. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=GBD+Chronic+Respiratory+Disease+Collaborator.+Prevalence+and+attributable+health+burden+of+chronic+respiratory+diseases,+1990-2017:+a+systematic+analysis+for+the+Global+Burden+of+Disease+Study+2017.">GBD Chronic Respiratory Disease Collaborator. 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disease.</a> Jilin Med J. 43 (10), 2852-2854 (2022).</li><li>Meiying, C., Limei, C., Weirong, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+effect+of+auricular+pressure+bean+combined+with+acupoint+patch+on+treatment+adherence+and+lung+function+in+elderly+COPD+patients.">The effect of auricular pressure bean combined with acupoint patch on treatment adherence and lung function in elderly COPD patients.</a> Mod Nurse. 30 (2), 129-131 (2023).</li><li>Qiubo, D., Keming, Z. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+probe+into+the+etiology+and+pathogenesis+of+wheezing+disease-asthmatic+syndrome-lung+distension.">A probe into the etiology and pathogenesis of wheezing disease-asthmatic syndrome-lung distension.</a> J Pract Tradl Chinese Int Med. , 1-5 (2023).</li><li>Biying, L., Haina, L., Jinrong, 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Med Uni. 46 (7), 757-760 (2022).</li><li>Yan, L., Lei, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effectiveness+of+auricular+point+pressure+bean+combined+with+acupressure+in+patients+with+chronic+obstructive+pulmonary+disease.">Effectiveness of auricular point pressure bean combined with acupressure in patients with chronic obstructive pulmonary disease.</a> Modern Nurse. 25 (8), 87-90 (2018).</li><li>Lin, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Factors+influencing+compliance+with+auricular+acupressure+therapy+in+patients+with+cancer-related+fatigue.">Factors influencing compliance with auricular acupressure therapy in patients with cancer-related fatigue.</a> Patient Prefer Adherence. 14, 1275-1281 (2020).</li><li>Lijuan, C., et al. <a target="_blank" 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<table border="1" fo:keep-together.within-page="1" fo:keep-with-next.within-page="always">
	<tbody>
		<tr>
			<td>Auricular acupressure patch template</td>
			<td>Hengshui Runhuang Trading Co., Ltd</td>
			<td></td>
			<td></td>
		</tr>
		<tr>
			<td>Cotton balls with 75% ethanol</td>
			<td>Qingdao Hainuo Biological Engineering Co., Ltd</td>
			<td>20172640783</td>
			<td></td>
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			<td>Medical blades</td>
			<td>Suzhou Kaiyuan Medical Equipment Co., Ltd</td>
			<td>20192020831</td>
			<td></td>
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			<td>Medical tape</td>
			<td>Zhende Medical Supplies Co., Ltd</td>
			<td>20170090</td>
			<td></td>
		</tr>
		<tr>
			<td>Sterile forceps</td>
			<td>Yangzhou Zhixiang Medical Technology Co., Ltd</td>
			<td>20210081</td>
			<td></td>
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		<tr>
			<td>The seeds of Vaccaria segetalis</td>
			<td>Anhui Kang Yunuo Biotechnology Co., Ltd</td>
			<td>SC10334161107893</td>
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	</tbody>
</table>

auricular acupressure as an adjuvant treatment for wheezing in stable chronic obstructive pulmonary disease 

Read this Scientific Article Protocol about Auricular Acupressure as an Adjuvant Treatment for Wheezing in Stable Chronic Obstructive Pulmonary Disease at JoVE.com

<meta charset="utf8"></head><body>作者聚焦：耳压豆疗法在减轻喘息症状方面的疗效

耳穴按压作为稳定期慢性阻塞性肺疾病喘息的辅助治疗 

Chronic obstructive pulmonary disease (COPD) is a major public health problem. Due to the restriction of expiratory airflow, it is characterized by ...

auricular-acupressure-as-an-adjuvant-treatment-for-wheezing-stable

Research

JoVE Journal

Medicine

Auricular Acupressure as an Adjuvant Treatment for Wheezing in Stable Chronic Obstructive Pulmonary Disease 

660 次观看.  University of Traditional Chinese Medicine. 该方案研究了耳压豆疗法对稳定期慢性阻塞性肺疾病患者喘息症状的有效性。这种技术具有成本效益且易于操作。此外，它拥有很高的安全性，显着降低了感染的可能性。该方案为诊断为慢性阻塞性肺病的患者提供了一种新型辅助疗法，该疗法已在我们医院成功实施。

视频: 作者聚焦：耳压豆疗法在减轻喘息症状方面的疗效

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung parenchymal destruction. It has a very high incidence in aging populations. The current conventional therapies for COPD focus mainly on symptom-modifying drugs; thus, the development of new therapies is urgently needed. Qualified animal models of COPD could help to characterize the underlying mechanisms and can be used for new drug screening. Current COPD models, such as lipopolysaccharide (LPS) or the porcine pancreatic elastase (PPE)-induced emphysema model, generate COPD-like lesions in the lungs and airways but do not otherwise resemble the pathogenesis of human COPD. A cigarette smoke (CS)-induced model remains one of the most popular because it not only simulates COPD-like lesions in the respiratory system, but it is also based on one of the main hazardous materials that causes COPD in humans. However, the time-consuming and labor-intensive aspects of the CS-induced model dramatically limit its application in new drug screening. In this study, we successfully generated a new COPD model by exposing mice to high levels of ozone. This model demonstrated the following: 1) decreased forced expiratory volume 25, 50, and 75/forced vital capacity (FEV25/FVC, FEV50/FVC, and FEV75/FVC), indicating the deterioration of lung function; 2) enlarged lung alveoli, with lung parenchymal destruction; 3) reduced fatigue time and distance; and 4) increased inflammation. Taken together, these data demonstrate that the ozone exposure (OE) model is a reliable animal model that is similar to humans because ozone overexposure is one of the etiological factors of COPD. Additionally, it only took 6 - 8 weeks, based on our previous work, to create an OE model, whereas it requires 3 - 12 months to induce the cigarette smoke model, indicating that the OE model might be a good choice for COPD research.

This study describes the successful generation of a new chronic obstructive pulmonary disease (COPD) animal model by repeatedly exposing mice to high concentrations of ozone.

反复臭氧暴露对小鼠慢性阻塞性肺疾病模型的产生

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung parenchymal destruction. It has a very high ...

科研

医学

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a common and frequent disease in elderly patients, with a tendency for progressive exacerbation. Constipation that reduces the quality of life and triggers the risk of diseases is a common concomitant symptom in patients with COPD. Currently, western medical treatment does not achieve the desired results for patients. A high recurrence rate accompanies it, whereas traditional Chinese medicine (TCM) has a long history and rich experience in treating chronic diseases. Both acupoint application and acupoint massage are characteristic therapies of TCM, with minor side effects, high safety, simple operation, and outstanding advantages. They are effective in treating constipation for patients with COPD and are considered an ideal alternative therapy for patients with chronic constipation. The purpose of this article is to introduce the method of acupoint application combined with acupoint massage for the treatment of constipation in patients with COPD, including the selection of points, items, treatment time, and operation procedure.

Here we demonstrate acupoint application combined with acupoint massage for treating constipation in a patient with chronic obstructive pulmonary disease (COPD).

穴位应用联合穴位按摩治疗慢性阻塞性肺疾病患者便秘

Chronic obstructive pulmonary disease (COPD) is a common and frequent disease in elderly patients, with a tendency for progressive exacerbation. ...

针灸刺激耳朵以缓解 COPD 患者的睡眠障碍

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Chronic obstructive pulmonary disease (COPD) is a clinical syndrome characterized by persistent and irreversible airflow limitation and chronic respiratory symptoms. It has a wide spectrum of complications, and sleep disorders, as part of it, are common in severe cases, especially in elderly patients. Long-term lack of sleep may lead to the aggravation of the original disease, reducing patients' quality of life. Benzodiazepines are mainly used for symptomatic treatment of COPD combined with sleep disorders. However, such drugs have the side effect of respiratory central inhibition and could probably aggravate hypoxia symptoms. Auricular acupuncture is a special method of treating physical and psychosomatic dysfunctions by stimulating specific points in the ear. This article explains the specific methods of clinical operation of auricular acupuncture in detail, including assessment of patient eligibility, medical devices used, acupuncture points, course of treatment, post-treatment care, responses to emergencies, etc. The Pittsburgh sleep quality index (PSQI) and chronic obstructive pulmonary disease assessment scale (CAT) were used as the observational index of this method. So far, clinical reports have proved that auricular acupuncture has a definite curative effect in the treatment of COPD combined with sleep disorders, and its advantages of simple operation, few adverse reactions are worthy of further study and promotion, which provide a reference for the clinical treatment of such diseases.

作者聚焦：利用中医耳针疗法改善睡眠障碍 

This protocol introduces an effective method to improve the sleep condition of patients with chronic obstructive pulmonary disease and alleviate cough symptoms by using auricular acupuncture techniques to percutaneously stimulate specific acupoints in the patients' ears.

耳针作为慢性阻塞性肺疾病合并睡眠障碍的中医疗法

Chronic obstructive pulmonary disease (COPD) is a clinical syndrome characterized by persistent and irreversible airflow limitation and chronic ...

温针灸缓解慢性阻塞性肺病腹胀

A Preliminary Study on Warm Acupuncture and Moxibustion for Treating Chronic Obstructive Pulmonary Disease with Abdominal Distension

Most patients with COPD have a combination of abdominal distension, which has been shown to adversely affect pulmonary symptoms, frequency of acute exacerbations, and quality of life in patients with COPD. Warm acupuncture and moxibustion have been shown to be effective in relieving symptoms in patients with COPD combined with abdominal distention. Warm acupuncture and moxibustion are highly effective, easy to perform, and inexpensive forms of traditional Chinese medicine treatments. The standardized practice of warm acupuncture and moxibustion is very important for the treatment of COPD combined with abdominal distension. The specific steps include selecting the appropriate acupoints for needling through syndrome differentiation treatment and selecting moxa sticks of appropriate length for moxibustion for about 30 min after the De-qi. The course of treatment lasts for one week. The following indicators are specifically assessed: the score of the COPD Assessment Test (CAT) and the abdominal distension visual analog scale (VAS). This article will clearly illustrate how to standardize the manipulation of warm acupuncture and moxibustion to relieve COPD combined with abdominal distention.

作者聚焦：慢性阻塞性肺疾病腹胀的有效中医治疗方法 

Here, we present a protocol to properly manipulate warm acupuncture and moxibustion for treating chronic obstructive pulmonary disease (COPD) with abdominal distension.

温针灸治疗慢性阻塞性肺疾病伴腹胀的初步研究

Most patients with COPD have a combination of abdominal distension, which has been shown to adversely affect pulmonary symptoms, frequency of acute ...

<meta charset="utf8"></head><body>用于疾病检测和监测的高级肺部成像

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment

Fourier decomposition is a contrast agent-free 1H MRI method for lung perfusion (Q) and ventilation (V) assessment. After image registration, the time series of each voxel is analyzed with regard to the cardiac and breathing frequency components.
Using a standard 2D spoiled gradient-echo sequence with a temporal resolution of ~300 ms, an image-sorting algorithm was developed to produce phase-resolved functional lung imaging (PREFUL) with an increased temporal resolution. Thus, it is feasible to evaluate regional flow volume loops (FVL) during tidal volume breathing and depict the propagation of the pulse wave during the cardiac cycle. This method can be applied at 1.5T or 3T with standard MR hardware without the necessity for sequence programming, as the described protocol can be implemented with the default SPGRE sequence on most systems.
PREFUL ventilation MRI has been validated using 129Xe and 19F gas imaging with good regional agreement. Perfusion-weighted PREFUL MRI has been validated using SPECT as well as dynamic contrast enhanced (DCE) MRI. PREFUL has been tested in a dual center dual vendor setting and is currently applied in several ongoing multicenter trials. Furthermore, it is feasible across a range of field strengths (0.55T-3T) and different age groups, including newborns.
Quantitative V/Q PREFUL MRI has been used in patients with cystic fibrosis, chronic obstructive pulmonary disease, chronic thromboembolic pulmonary hypertension, and corona virus disease-2019 to quantify disease and monitor treatment change after therapy. Furthermore, PREFUL V/Q imaging has been shown to predict transplant loss due to chronic lung allograft dysfunction in patients after lung transplantation. In summary, PREFUL MRI is a validated technique for quantitative ventilation and pulmonary pulse wave/perfusion imaging for regional pulmonary disease detection, quantification, and treatment monitoring with potential added value to the current clinical routine.

<meta charset="utf8"></head><body>作者聚焦：增强诊断策略和生物标志物开发以进行全面肺功能分析

Here, we describe the implementation of phase-resolved functional lung MRI as a contrast-agent-free proton MR technique for the assessment of pulmonary ventilation and perfusion dynamics. Validated and applicable across different field strengths and age groups, it could enhance clinical decision-making in the future by aiding in disease quantification and therapy monitoring.

用于肺通气和灌注 （V/Q） 评估的相位分辨功能性肺 MRI

Fourier decomposition is a contrast agent-free 1H MRI method for lung perfusion (Q) and ventilation (V) assessment. After image registration, the time ...

Methods Article

耳穴按压作为稳定期慢性阻塞性肺疾病喘息的辅助治疗