专访：HIV - 1前病毒DNA切除使用一个演进的重组酶
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June 16th, 2008
DOI :
June 16th, 2008
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What are limitations of today's antiretroviral therapies
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Title
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Excision of proviral DNA. Targeting LTR specific sequences.
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Addressing the problem of multiple HIV isolates.
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Generation of site-specific Tre recombinase via directed molecular evolution.
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Delivery of Tre recombinase, HIV-1 proviral DNA excision, and elimination of HIV-1 viruses.
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Open questions.
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Towards a clinical application.
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