David Kleinfeld

Cortical imaging through the intact mouse skull using two-photon excitation laser scanning microscopy.

Coherent electrical activity between vibrissa sensory areas of cerebellum and neocortex is enhanced during free whisking.

Adaptive filtering of vibrissa input in motor cortex of rat.

Spectral mixing of rhythmic neuronal signals in sensory cortex.

Closed-loop neuronal computations: focus on vibrissa somatosensation in rat.

Rhythmic whisking by rat: retraction as well as protraction of the vibrissae is under active muscular control.

All-optical histology using ultrashort laser pulses.

Unilateral vibrissa contact: changes in amplitude but not timing of rhythmic whisking.

Vibrissa movement elicited by rhythmic electrical microstimulation to motor cortex in the aroused rat mimics exploratory whisking.

Reversing cerebellar long-term depression.

Imaging reveals synaptic targets of a swim-terminating neuron in the leech CNS.

Frisking the whiskers: patterned sensory input in the rat vibrissa system.

Developmental regulation of active and passive membrane properties in rat vibrissa motoneurones.

Goal-directed whisking increases phase-locking between vibrissa movement and electrical activity in primary sensory cortex in rat.

Current flow in vibrissa motor cortex can phase-lock with exploratory rhythmic whisking in rat.

Positive feedback in a brainstem tactile sensorimotor loop.

Activation of nucleus basalis facilitates cortical control of a brain stem motor program.

From art to engineering? The rise of in vivo mammalian electrophysiology via genetically targeted labeling and nonlinear imaging.

Coding of stimulus frequency by latency in thalamic networks through the interplay of GABAB-mediated feedback and stimulus shape.

Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion.

Science is an adventure, not a battle.

Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke.

MPScope: a versatile software suite for multiphoton microscopy.

Seeing what the mouse sees with its vibrissae: a matter of behavioral state.

Exploratory whisking by rat is not phase locked to the hippocampal theta rhythm.

Active sensation: insights from the rodent vibrissa sensorimotor system.

Penetrating arterioles are a bottleneck in the perfusion of neocortex.

Is there a common origin to surround-inhibition as seen through electrical activity versus hemodynamic changes? Focus on "Duration-dependent response in SI to vibrotactile stimulation in squirrel monkey".

Active spatial perception in the vibrissa scanning sensorimotor system.

Large two-photon absorptivity of hemoglobin in the infrared range of 780-880 nm.

Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative blood oxygenation level-dependent signal.

Wilder Penfield in the age of YouTube: visualizing the sequential activation of sensorimotor areas across neocortex.

Biomechanics of the vibrissa motor plant in rat: rhythmic whisking consists of triphasic neuromuscular activity.

'Where' and 'what' in the whisker sensorimotor system.

Finding coherence in spontaneous oscillations.

Texture coding in the rat whisker system: slip-stick versus differential resonance.

Advancing multifocal nonlinear microscopy: development and application of a novel multibeam Yb:KGd(WO4)2 oscillator.

Chapter 10. In vivo measurements of blood flow and glial cell function with two-photon laser-scanning microscopy.

Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortex.

Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke.

Plasma-mediated ablation: an optical tool for submicrometer surgery on neuronal and vascular systems.

Phase-to-rate transformations encode touch in cortical neurons of a scanning sensorimotor system.

A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale.

Acute vascular disruption and aquaporin 4 loss after stroke.

Rapid determination of particle velocity from space-time images using the Radon transform.

The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice.

Severe blood-brain barrier disruption and surrounding tissue injury.

Enter the ratrix.

Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels.

An in vivo biosensor for neurotransmitter release and in situ receptor activity.

Optimizing the fluorescent yield in two-photon laser scanning microscopy with dispersion compensation.

Automatic identification of fluorescently labeled brain cells for rapid functional imaging.

Topological basis for the robust distribution of blood to rodent neocortex.

Temporally focused femtosecond laser pulses for low numerical aperture micromachining through optically transparent materials.

Chronic optical access through a polished and reinforced thinned skull.

Spatio-temporally focused femtosecond laser pulses for nonreciprocal writing in optically transparent materials.

Characterizing ligand-gated ion channel receptors with genetically encoded Ca2++ sensors.

Photon counting, censor corrections, and lifetime imaging for improved detection in two-photon microscopy.

Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity.

A guide to delineate the logic of neurovascular signaling in the brain.

Quality metrics to accompany spike sorting of extracellular signals.

Primary motor cortex reports efferent control of vibrissa motion on multiple timescales.

Large-scale automated histology in the pursuit of connectomes.

Neuronal basis for object location in the vibrissa scanning sensorimotor system.

Prospect for feedback guided surgery with ultra-short pulsed laser light.

Sniffing and whisking in rodents.

Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain.

Interferometric detection of action potentials.

Dorsorostral snout muscles in the rat subserve coordinated movement for whisking and sniffing.

Vectorization of optically sectioned brain microvasculature: learning aids completion of vascular graphs by connecting gaps and deleting open-ended segments.

The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit.

All-optical in situ histology of brain tissue with femtosecond laser pulses.

Hierarchy of orofacial rhythms revealed through whisking and breathing.

The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow.

Two-photon imaging of blood flow in the rat cortex.

ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation.

All-optical osteotomy to create windows for transcranial imaging in mice.

The challenge of connecting the dots in the B.R.a.I.N.

Mediation of muscular control of rhinarial motility in rats by the nasal cartilaginous skeleton.

Optically induced occlusion of single blood vessels in rodent neocortex.

Spectral methods for functional brain imaging.

More than a rhythm of life: breathing as a binder of orofacial sensation.

How the brainstem controls orofacial behaviors comprised of rhythmic actions.

Activation and measurement of free whisking in the lightly anesthetized rodent.

Muscles involved in naris dilation and nose motion in rat.

Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex.

The Musculature That Drives Active Touch by Vibrissae and Nose in Mice.

Feedback in the brainstem: an excitatory disynaptic pathway for control of whisking.

Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture.

Fluorescently Labeled Peptide Increases Identification of Degenerated Facial Nerve Branches during Surgery and Improves Functional Outcome.

Deflection of a vibrissa leads to a gradient of strain across mechanoreceptors in a mystacial follicle.

The Brainstem Oscillator for Whisking and the Case for Breathing as the Master Clock for Orofacial Motor Actions.