Smita Jagtap

Center of Physiology and Pathophysiology,
Institute of Neurophysiology,
Center of Physiology and Pathophysiology, Institute of Neurophysiology

University of Cologne

BIOGRAPHY

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PUBLICATIONS

Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and curcumin against cancer and cardiovascular diseases.

Current medicinal chemistry , 2009 | Pubmed ID: 19355899

Effects of cryopreservation on the transcriptome of human embryonic stem cells after thawing and culturing.

Stem cell reviews Sep, 2011 | Pubmed ID: 21279480

Functional characterization and gene expression profiling of α-smooth muscle actin expressing cardiomyocytes derived from murine induced pluripotent stem cells.

Stem cell reviews Mar, 2012 | Pubmed ID: 21567216

Development of a neural teratogenicity test based on human embryonic stem cells: response to retinoic acid exposure.

Toxicological sciences : an official journal of the Society of Toxicology Dec, 2011 | Pubmed ID: 21934132

Effect of chemopreventive agents on differentiation of mouse embryonic stem cells.

Frontiers in bioscience (Elite edition) , 2012 | Pubmed ID: 22201861

Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome.

Human molecular genetics Sep, 2012 | Pubmed ID: 22723015

Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.

PloS one , 2012 | Pubmed ID: 22952932

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.

Archives of toxicology Jan, 2013 | Pubmed ID: 23179753

Current status of human pluripotent stem cell based in vitro toxicity tests.

Frontiers in bioscience (Scholar edition) , 2013 | Pubmed ID: 23277040

All-trans retinoic acid and basic fibroblast growth factor synergistically direct pluripotent human embryonic stem cells to extraembryonic lineages.

Stem cell research Mar, 2013 | Pubmed ID: 23314291

Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies.

Stem cell reviews Feb, 2014 | Pubmed ID: 24022811

A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system.

Toxicology letters Nov, 2014 | Pubmed ID: 25192806

INSTITUTIONS

University of Cologne

JOVE ARTICLES

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Vaibhav Shinde^*,1,

Stefanie Klima^*,2,

Perumal Srinivasan Sureshkumar¹,

Kesavan Meganathan¹,

Smita Jagtap¹,

Eugen Rempel³,

Jörg Rahnenführer³,

Jan Georg Hengstler⁴,

Tanja Waldmann²,

Jürgen Hescheler¹,

Marcel Leist^*,2,

Agapios Sachinidis^*,1

¹Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne,

²Department of Biology, University of Konstanz,

³Department of Statistics, Technical University of Dortmund,

⁴Leibniz Research Centre for Working Environment and Human Factors, Technical University of Dortmund

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Smita Jagtap

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Center of Physiology and Pathophysiology,Institute of Neurophysiology,Center of Physiology and Pathophysiology, Institute of Neurophysiology

University of Cologne

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Center of Physiology and Pathophysiology,
Institute of Neurophysiology,
Center of Physiology and Pathophysiology, Institute of Neurophysiology