Tobias Moser

LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice.

Calcium regulates exocytosis at the level of single vesicles.

The afferent synapse of cochlear hair cells.

CaV1.3 channels are essential for development and presynaptic activity of cochlear inner hair cells.

BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments.

Hair cell synaptic ribbons are essential for synchronous auditory signalling.

Few CaV1.3 channels regulate the exocytosis of a synaptic vesicle at the hair cell ribbon synapse.

Expression pattern and functional characterization of connexin29 in transgenic mice.

Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness.

CSPalpha-deficiency causes massive and rapid photoreceptor degeneration.

Mechanisms underlying the temporal precision of sound coding at the inner hair cell ribbon synapse.

Hair cell ribbon synapses.

[Hearing loss -- can heat shock protein 70 be cited as prognostic marker?].

Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse.

Intracavity generation of radially polarized CO2 laser beams based on a simple binary dielectric diffraction grating.

Measurements of membrane patch capacitance using a software-based lock-in system.

Maturation of ribbon synapses in hair cells is driven by thyroid hormone.

Ca2+-binding proteins tune Ca2+-feedback to Cav1.3 channels in mouse auditory hair cells.

Probing the mechanism of exocytosis at the hair cell ribbon synapse.

Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice.

Mechanisms contributing to synaptic Ca2+ signals and their heterogeneity in hair cells.

Tuning of synapse number, structure and function in the cochlea.

Does a single session of theta-burst transcranial magnetic stimulation of inferior temporal cortex affect tinnitus perception?

Complexin-I is required for high-fidelity transmission at the endbulb of Held auditory synapse.

Neuroligin 2 controls the maturation of GABAergic synapses and information processing in the retina.

The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing.

Functional properties of synaptic transmission in primary sense organs.

Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons.

Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells.

A missense mutation in a highly conserved alternate exon of dynamin-1 causes epilepsy in fitful mice.

Structure and function of cochlear afferent innervation.

The connexin26 S17F mouse mutant represents a model for the human hereditary keratitis-ichthyosis-deafness syndrome.

Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refilling.

The crystal structure of the C₂A domain of otoferlin reveals an unconventional top loop region.

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.

Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins.

Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.

A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity.

Connexin32 can restore hearing in connexin26 deficient mice.

Harmonin inhibits presynaptic Cav1.3 Ca²⁺ channels in mouse inner hair cells.

Spike encoding of neurotransmitter release timing by spiral ganglion neurons of the cochlea.

The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative gene.

Deletion of the presynaptic scaffold CAST reduces active zone size in rod photoreceptors and impairs visual processing.

Otoferlin: a multi-C2 domain protein essential for hearing.

A mutation in CABP2, expressed in cochlear hair cells, causes autosomal-recessive hearing impairment.

A Mutation in PNPT1, Encoding Mitochondrial-RNA-Import Protein PNPase, Causes Hereditary Hearing Loss.

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system.

Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells.

Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse.

Harmonin enhances voltage-dependent facilitation of Cav1.3 channels and synchronous exocytosis in mouse inner hair cells.

Review of hair cell synapse defects in sensorineural hearing impairment.

Concurrent maturation of inner hair cell synaptic Ca2+ influx and auditory nerve spontaneous activity around hearing onset in mice.

Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.

Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis.

Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse.

Optogenetic stimulation of the auditory pathway.

ATP hydrolysis is critically required for function of CaV1.3 channels in cochlear inner hair cells via fueling Ca2+ clearance.

A new probe for super-resolution imaging of membranes elucidates trafficking pathways.

Uniquantal Release through a Dynamic Fusion Pore Is a Candidate Mechanism of Hair Cell Exocytosis.