Department of Ophthalmology,
Yong Loo Lin School of Medicine,
Department of Ophthalmology, Yong Loo Lin School of Medicine
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A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway.
Nature communications May, 2022 | Pubmed ID: 35589753
Interaction of gelatin with polyenes modulates antifungal activity and biocompatibility of electrospun fiber mats.
International journal of nanomedicine , 2014 | Pubmed ID: 24920895
A biodegradable ocular implant for long-term suppression of intraocular pressure.
Drug delivery and translational research Oct, 2015 | Pubmed ID: 26100093
Latent Oxidative Polymerization of Catecholamines as Potential Cross-linkers for Biocompatible and Multifunctional Biopolymer Scaffolds.
ACS applied materials & interfaces Nov, 2016 | Pubmed ID: 27800687
Antimicrobial Activity and Cell Selectivity of Synthetic and Biosynthetic Cationic Polymers.
Antimicrobial agents and chemotherapy Oct, 2017 | Pubmed ID: 28784676
A novel model of persistent retinal neovascularization for the development of sustained anti-VEGF therapies.
Experimental eye research Sep, 2018 | Pubmed ID: 29852133
Surface characteristics and antimicrobial properties of modified catheter surfaces by polypyrogallol and metal ions.
Materials science & engineering. C, Materials for biological applications Sep, 2018 | Pubmed ID: 29853139
The penetration and distribution of topical atropine in animal ocular tissues.
Acta ophthalmologica Mar, 2019 | Pubmed ID: 30259687
Quantitative analysis of choriocapillaris in non-human primates using swept-source optical coherence tomography angiography (SS-OCTA).
Biomedical optics express Jan, 2019 | Pubmed ID: 30775105
Retinal-detachment repair and vitreous-like-body reformation via a thermogelling polymer endotamponade.
Nature biomedical engineering 08, 2019 | Pubmed ID: 30962587
In-utero epigenetic factors are associated with early-onset myopia in young children.
PloS one , 2019 | Pubmed ID: 31100065
Apratoxin S4 Inspired by a Marine Natural Product, a New Treatment Option for Ocular Angiogenic Diseases.
Investigative ophthalmology & visual science 07, 2019 | Pubmed ID: 31361305
Sustained delivery of anti-VEGFs from thermogel depots inhibits angiogenesis without the need for multiple injections.
Biomaterials science Nov, 2019 | Pubmed ID: 31436780
corneal endothelium imaging using ultrahigh resolution OCT.
Biomedical optics express Nov, 2019 | Pubmed ID: 31799039
Effects of Exogenous Neuroglobin (Ngb) on retinal inflammatory chemokines and microglia in a rat model of transient hypoxia.
Scientific reports 12, 2019 | Pubmed ID: 31827177
Multifunctional Antimicrobial Nanofiber Dressings Containing ε-Polylysine for the Eradication of Bacterial Bioburden and Promotion of Wound Healing in Critically Colonized Wounds.
ACS applied materials & interfaces Apr, 2020 | Pubmed ID: 32172559
Rational Substitution of ε-Lysine for α-Lysine Enhances the Cell and Membrane Selectivity of Pore-Forming Melittin.
Journal of medicinal chemistry 04, 2020 | Pubmed ID: 32175733
Wound healing properties of magnesium mineralized antimicrobial nanofibre dressings containing chondroitin sulphate - a comparison between blend and core-shell nanofibres.
Biomaterials science Jun, 2020 | Pubmed ID: 32420550
Investigating the Role of PPARβ/δ in Retinal Vascular Remodeling Using /-Deficient Mice.
International journal of molecular sciences Jun, 2020 | Pubmed ID: 32575793
Noninvasive and Noncontact Sequential Imaging of the Iridocorneal Angle and the Cornea of the Eye.
Translational vision science & technology 04, 2020 | Pubmed ID: 32821473
Longitudinal assessment of optic nerve head changes using optical coherence tomography in a primate microbead model of ocular hypertension.
Scientific reports 09, 2020 | Pubmed ID: 32895414
Endogenous or Exogenous Retinal Pigment Epithelial Cells: A Comparison of Two Experimental Animal Models of Proliferative Vitreoretinopathy.
Translational vision science & technology Aug, 2020 | Pubmed ID: 32934896
Differential reperfusion patterns in retinal vascular plexuses following increase in intraocular pressure an OCT angiography study.
Scientific reports Oct, 2020 | Pubmed ID: 33020568
Surgical Transplantation of Human RPE Stem Cell-Derived RPE Monolayers into Non-Human Primates with Immunosuppression.
Stem cell reports Feb, 2021 | Pubmed ID: 33450191
Choroidal and Retinal Changes After Systemic Adrenaline and Photodynamic Therapy in Non-Human Primates.
Investigative ophthalmology & visual science Mar, 2021 | Pubmed ID: 33729474
Core-Shell Structured Antimicrobial Nanofiber Dressings Containing Herbal Extract and Antibiotics Combination for the Prevention of Biofilms and Promotion of Cutaneous Wound Healing.
ACS applied materials & interfaces Jun, 2021 | Pubmed ID: 34024104
Submacular integration of hESC-RPE monolayer xenografts in a surgical non-human primate model.
Stem cell research & therapy Jul, 2021 | Pubmed ID: 34315534
cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates.
Stem cell research & therapy Aug, 2021 | Pubmed ID: 34412697
Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis.
Scientific reports Sep, 2021 | Pubmed ID: 34526600
Antiangiogenic Nanomicelles for the Topical Delivery of Aflibercept to Treat Retinal Neovascular Disease.
Advanced materials (Deerfield Beach, Fla.) Jun, 2022 | Pubmed ID: 34726299
Gene-Based Therapeutics for Acquired Retinal Disease: Opportunities and Progress.
Frontiers in genetics , 2021 | Pubmed ID: 34950193
Local Dexamethasone Administration Delays Allogeneic Islet Graft Rejection in the Anterior Chamber of the Eye of Non-Human Primates.
Cell transplantation , 2022 | Pubmed ID: 35603580
Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid.
International journal of molecular sciences Sep, 2022 | Pubmed ID: 36142120
Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2023 | Pubmed ID: 36638800
Applications of Genomics and Transcriptomics in Precision Medicine for Myopia Control or Prevention.
Biomolecules Mar, 2023 | Pubmed ID: 36979429
Propranolol Ameliorates the Antifungal Activity of Azoles in Invasive Candidiasis.
Pharmaceutics Mar, 2023 | Pubmed ID: 37111530
Akimba Proliferative Diabetic Retinopathy Model: Understanding Molecular Mechanism and Drug Screening for the Progression of Diabetic Retinopathy.
Methods in molecular biology (Clifton, N.J.) , 2023 | Pubmed ID: 37326702
Single-cell transcriptomics reveals maturation of transplanted stem cell-derived retinal pigment epithelial cells toward native state.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2023 | Pubmed ID: 37339216
Depleted hexokinase1 and lack of AMPKα activation favor OXPHOS-dependent energetics in retinoblastoma tumors.
Translational research : the journal of laboratory and clinical medicine Nov, 2023 | Pubmed ID: 37419277
Molecular Basis of Transglutaminase-2 and Muscarinic Cholinergic Receptors in Experimental Myopia: A Target for Myopia Treatment.
Biomolecules Jun, 2023 | Pubmed ID: 37509081
Ivan Seah*,1,2,
Zengping Liu*,1,3,4,
Daniel Soo Lin Wong1,
Wendy Wong2,
Graham E. Holder1,2,5,
Veluchamy Amutha Barathi1,4,6,
Gopal Lingam1,2,4,
Xinyi Su1,2,3,4,
Boris V. Stanzel1,7,8
1Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore,
2Department of Ophthalmology, National University Hospital, Singapore,
3Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR),
4, Singapore Eye Research Institute (SERI),
5, UCL Institute of Ophthalmology,
6Academic Clinical Program in Ophthalmology, Duke-NUS Medical School,
7Macula Center Saar, Eye Clinic Sulzbach, Knappschaft Hospital Saar,
8Department of Ophthalmology, University of Bonn
1Singapore National Eye Centre, Singapore Eye Research Institute,
2Centre for Vision Research, Duke-NUS Medical School,
3Ophthalmology and Visual Sciences Academic Clinical Program, DUKE-NUS Medical School,
4Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore
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