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Assessing Tumor Microenvironment of Metastasis Doorway-Mediated Vascular Permeability Associated with Cancer Cell Dissemination using Intravital Imaging and Fixed Tissue Analysis

8.6K Views

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09:42 min

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June 26th, 2019

DOI :

10.3791/59633-v

June 26th, 2019

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8,630 Views

George S. Karagiannis^1,2,3, Jessica M. Pastoriza^1,2,4, Lucia Borriello^1,2, Rojin Jafari^1,2, Anouchka Coste^1,2,4, John S. Condeelis^1,2,3,4, Maja H. Oktay^1,2,3,5, David Entenberg^1,2,3

¹Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, ²Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, ³Integrated Imaging Program, Albert Einstein College of Medicine, ⁴Department of Surgery, Montefiore Medical Center, ⁵Department of Pathology, Montefiore Medical Center

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Keywords Tumor Microenvironment

Vascular Permeability

Cancer Cell Dissemination

Intravital Imaging

Fixed Tissue Analysis

Tumor Transplantation

Mammary Fat Pad

Extracellular Matrix

Tail Vein Catheter

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