Dirk Bohmann

The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription.

An essential function of AP-1 heterodimers in Drosophila development.

Transrepression of AP-1 by nuclear receptors in Drosophila.

Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome.

Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation.

A genomic switch at the transition from cell proliferation to terminal differentiation in the Drosophila eye.

Drosophila innate immunity: a genomic view of pathogen defense.

JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun.

JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila.

Deregulated repression of c-Jun provides a potential link to its role in tumorigenesis.

DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway.

Toward the computable transcriptome.

Small flies--big discoveries: nearly a century of Drosophila genetics and development.

JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling.

Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons.

DREF is required for efficient growth and cell cycle progression in Drosophila imaginal discs.

Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model.

JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis.

Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis.

Control of G2/M transition by Drosophila Fos.

JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila.

Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation.

Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila.

JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy.

Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis.

Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis.

Stress-activated cap'n'collar transcription factors in aging and human disease.

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation.

Computational systems biology of aging.

Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila.

c-Jun localizes to the nucleus independent of its phosphorylation by and interaction with JNK and vice versa promotes nuclear accumulation of JNK.

Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease.

A versatile ΦC31 based reporter system for measuring AP-1 and Nrf2 signaling in Drosophila and in tissue culture.

Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress.

Declining signal-dependence of Nrf2-MafS regulated gene expressioncorrelates with aging phenotypes.