Gaudenz Danuser

Single muscle fiber contraction is dictated by inter-sarcomere dynamics.

New directions for fluorescent speckle microscopy.

Microcontact printing of novel co-polymers in combination with proteins for cell-biological applications.

FRET or no FRET: a quantitative comparison.

Simultaneous mapping of filamentous actin flow and turnover in migrating cells by quantitative fluorescent speckle microscopy.

Tracking retrograde flow in keratocytes: news from the front.

Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin.

Integrin-dependent actomyosin contraction regulates epithelial cell scattering.

Kinesin 5-independent poleward flux of kinetochore microtubules in PtK1 cells.

Quantitative fluorescent speckle microscopy of cytoskeleton dynamics.

Comparative autoregressive moving average analysis of kinetochore microtubule dynamics in yeast.

Linking data to models: data regression.

Differential transmission of actin motion within focal adhesions.

Positional stability of single double-strand breaks in mammalian cells.

Probing intracellular force distributions by high-resolution live cell imaging and inverse dynamics.

Locomotion of fish epidermal keratocytes on spatially selective adhesion patterns.

Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility.

Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging.

Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks.

Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones.

Computational processing and analysis of dynamic fluorescence image data.

Visualizing and quantifying adhesive signals.

Coordination of actin filament and microtubule dynamics during neurite outgrowth.

Myosin II activity facilitates microtubule bundling in the neuronal growth cone neck.

Robust single-particle tracking in live-cell time-lapse sequences.

Regional variation of microtubule flux reveals microtubule organization in the metaphase meiotic spindle.

Fluctuations of intracellular forces during cell protrusion.

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed.

Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules.

GSK3beta phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment.

Cargo and dynamin regulate clathrin-coated pit maturation.

Endocytic accessory proteins are functionally distinguished by their differential effects on the maturation of clathrin-coated pits.

Testing the lamella hypothesis: the next steps on the agenda.

Global and local regulation of clathrin-coated pit dynamics detected on patterned substrates.

Coordination of Rho GTPase activities during cell protrusion.

Op18 reveals the contribution of nonkinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle.

Computational image analysis of cellular dynamics: a case study based on particle tracking.

Directly probing the mechanical properties of the spindle and its matrix.

Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases.

Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis.

Protrusion and actin assembly are coupled to the organization of lamellar contractile structures.

Modeling of protrusion phenotypes driven by the actin-membrane interaction.

Myosin II contributes to cell-scale actin network treadmilling through network disassembly.

Phosphatidic acid plays a regulatory role in clathrin-mediated endocytosis.

Analysis of microtubule dynamic instability using a plus-end growth marker.

Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability.

Local clustering of transferrin receptors promotes clathrin-coated pit initiation.

Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis.

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

Measuring the hierarchy of molecular events during clathrin-mediated endocytosis.

Protein kinase A governs a RhoA-RhoGDI protrusion-retraction pacemaker in migrating cells.

Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size.

Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration.

Optimal-Flow Minimum-Cost Correspondence Assignment in Particle Flow Tracking.

plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamics.

Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function.

Hotspots organize clathrin-mediated endocytosis by efficient recruitment and retention of nucleating resources.

What's wrong with correlative experiments?

High refractive index silicone gels for simultaneous total internal reflection fluorescence and traction force microscopy of adherent cells.

Imaging the coordination of multiple signalling activities in living cells.

Computer vision in cell biology.

Delivery of membrane impermeable cargo into CHO cells by peptide nanoparticles targeted by a protein corona.

Ovarian cancer spheroids use myosin-generated force to clear the mesothelium.