Joost Gribnau

Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.

Coordination of the random asynchronous replication of autosomal loci.

Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.

Derivation of embryonic germ cells and male gametes from embryonic stem cells.

X chromosome choice occurs independently of asynchronous replication timing.

X chromosomes alternate between two states prior to random X-inactivation.

X inactivation Xplained.

X inactivation counting and choice is a stochastic process: evidence for involvement of an X-linked activator.

Xist RNA is confined to the nuclear territory of the silenced X chromosome throughout the cell cycle.

CTCF regulates cell cycle progression of alphabeta T cells in the thymus.

The probability to initiate X chromosome inactivation is determined by the X to autosomal ratio and X chromosome specific allelic properties.

X chromosome inactivation is initiated in human preimplantation embryos.

RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation.

X-changing information on X inactivation.

A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.

A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression.

Evaluating the relationship between spermatogenic silencing of the X chromosome and evolution of the Y chromosome in chimpanzee and human.

X chromosome inactivation and embryonic stem cells.

Long Noncoding RNAs and X Chromosome Inactivation.

RNF12 activates Xist and is essential for X chromosome inactivation.

Xist regulation and function explored.

The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA.

Precise BAC targeting of genetically polymorphic mouse ES cells.

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors.

Origin and evolution of X chromosome inactivation.

Spatial partitioning of the regulatory landscape of the X-inactivation centre.

RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation.

RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation.

X chromosome inactivation in the cycle of life.

The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo.

Different flavors of X-chromosome inactivation in mammals.

Structural and numerical changes of chromosome X in patients with esophageal atresia.

The trans-activator RNF12 and cis-acting elements effectuate X chromosome inactivation independent of X-pairing.