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Department of Biochemistry
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Identification of a second proliferating cell nuclear antigen in the human malarial pathogen Plasmodium falciparum.
International journal for parasitology Dec, 2002 | Pubmed ID: 12464414
Characterisation of a sexual stage-specific gene encoding ORC1 homologue in the human malaria parasite Plasmodium falciparum.
Parasitology international Mar, 2003 | Pubmed ID: 12543146
Characterisation of the interaction between WRN, the helicase/exonuclease defective in progeroid Werner's syndrome, and an essential replication factor, PCNA.
Mechanisms of ageing and development Feb, 2003 | Pubmed ID: 12633936
Asymmetry of DNA replication fork progression in Werner's syndrome.
Aging cell Oct, 2002 | Pubmed ID: 12882351
Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.
Experimental cell research Feb, 2004 | Pubmed ID: 14729473
Correction of proliferation and drug sensitivity defects in the progeroid Werner's Syndrome by Holliday junction resolution.
Rejuvenation research Mar, 2007 | Pubmed ID: 17378750
Modeling Werner Syndrome in Drosophila melanogaster: hyper-recombination in flies lacking WRN-like exonuclease.
Annals of the New York Academy of Sciences Nov, 2007 | Pubmed ID: 18056975
Identification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity.
Aging cell Jun, 2008 | Pubmed ID: 18346216
DmWRNexo is a 3'-5' exonuclease: phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease.
Biogerontology Jun, 2009 | Pubmed ID: 18956248
Cell senescence: the future of ageing?
Biogerontology Jun, 2009 | Pubmed ID: 19115080
Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
Aging cell Sep, 2009 | Pubmed ID: 19678809
Live fast, die young: new lessons in mammalian longevity.
Rejuvenation research Aug, 2009 | Pubmed ID: 19725776
Prospects for rejuvenation of aged tissue by telomerase reactivation.
Rejuvenation research Dec, 2010 | Pubmed ID: 21226558
Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease.
Biogerontology Feb, 2012 | Pubmed ID: 21786128
The role of DNA exonucleases in protecting genome stability and their impact on ageing.
Age (Dordrecht, Netherlands) Dec, 2012 | Pubmed ID: 21948156
The Drosophila orthologue of progeroid human WRN exonuclease, DmWRNexo, cleaves replication substrates but is inhibited by uracil or abasic sites : analysis of DmWRNexo activity in vitro.
Age (Dordrecht, Netherlands) Jun, 2013 | Pubmed ID: 22562358
University of Oxford
Penelope A. Mason1,
Ivan Boubriak1,
Lynne S. Cox1
1Department of Biochemistry, University of Oxford
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