Department of Pediatric Oncology
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Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2002 | Pubmed ID: 11850459
Location, location, location: a spatial view of neurotrophin signal transduction.
Trends in neurosciences Mar, 2002 | Pubmed ID: 11852149
BDNF stimulates migration of cerebellar granule cells.
Development (Cambridge, England) Mar, 2002 | Pubmed ID: 11880352
小脑蛋白多糖在开发过程中调节声波刺猬的反应。
Development (Cambridge, England) May, 2002 | Pubmed ID: 11959830
Retrograde neurotrophin signaling: Trk-ing along the axon.
Current opinion in neurobiology Jun, 2002 | Pubmed ID: 12049932
Medulloblastomas and primitive neuroectodermal tumors rarely contain polyomavirus DNA sequences.
Neuro-oncology Jul, 2002 | Pubmed ID: 12084346
High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors.
Journal of neurobiology Jun, 2002 | Pubmed ID: 12150505
Regional expression of p75NTR contributes to neurotrophin regulation of cerebellar patterning.
Molecular and cellular neurosciences Jan, 2003 | Pubmed ID: 12595234
Selectivity in neurotrophin signaling: theme and variations.
Annual review of neuroscience , 2003 | Pubmed ID: 12598680
Growth, survival and migration: the Trk to cancer.
Cancer treatment and research , 2003 | Pubmed ID: 12613191
Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice.
Developmental biology Nov, 2003 | Pubmed ID: 14568546
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2003 | Pubmed ID: 14595012
Dynein motors transport activated Trks to promote survival of target-dependent neurons.
Nature neuroscience Jun, 2004 | Pubmed ID: 15122257
Subtracting the Math: prominin-positive cerebellar stem cells in white matter.
Nature neuroscience Jun, 2005 | Pubmed ID: 15917830
Migration from a mitogenic niche promotes cell-cycle exit.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2005 | Pubmed ID: 16280582
CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2006 | Pubmed ID: 17121897
Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors.
Neuron Jul, 2007 | Pubmed ID: 17610817
A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes.
The Journal of cell biology Jun, 2008 | Pubmed ID: 18559670
Action in the axon: generation and transport of signaling endosomes.
Current opinion in neurobiology Jun, 2008 | Pubmed ID: 18778772
Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses.
Nature neuroscience Apr, 2009 | Pubmed ID: 19287388
A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2009 | Pubmed ID: 19458239
Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27.
Developmental cell May, 2009 | Pubmed ID: 19460344
Live or let die: CCM2 provides the link.
Neuron Sep, 2009 | Pubmed ID: 19755097
The longer U(T)R, the further you go.
Nature neuroscience Mar, 2010 | Pubmed ID: 20177416
Sensory neuropathy attributable to loss of Bcl-w.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2011 | Pubmed ID: 21289171
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1.
PloS one , 2011 | Pubmed ID: 21346813
Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis.
Developmental cell May, 2011 | Pubmed ID: 21571219
From synapse to nucleus and back again--communication over distance within neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2011 | Pubmed ID: 22072654
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2013 | Pubmed ID: 23516285
Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation.
The Journal of biological chemistry Sep, 2013 | Pubmed ID: 23867465
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities.
Nature medicine Nov, 2013 | Pubmed ID: 24076665
New progenitors NESTIN(g) in the EGL.
Nature neuroscience Dec, 2013 | Pubmed ID: 24270268
Neuronal signaling through endocytosis.
Cold Spring Harbor perspectives in biology Feb, 2014 | Pubmed ID: 24492712
Pediatric low-grade gliomas: how modern biology reshapes the clinical field.
Biochimica et biophysica acta Apr, 2014 | Pubmed ID: 24589977
Shh-proteoglycan interactions regulate maturation of olfactory glomerular circuitry.
Developmental neurobiology Dec, 2014 | Pubmed ID: 24913191
Preserve and protect: maintaining axons within functional circuits.
Trends in neurosciences Oct, 2014 | Pubmed ID: 25167775
The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.
Developmental cell Apr, 2015 | Pubmed ID: 25816987
RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors.
Cancer research Sep, 2015 | Pubmed ID: 26130651
How neuronal activity regulates glioma cell proliferation.
Neuro-oncology Sep, 2015 | Pubmed ID: 26359210
A Polyamine Twist on Hedgehog Signaling.
Developmental cell Oct, 2015 | Pubmed ID: 26460938
Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons.
Cell reports Oct, 2015 | Pubmed ID: 26489457
Emily J. Chadwick1,
David P. Yang1,
Mariella G. Filbin2,
Emanuele Mazzola3,
Yu Sun1,
Oded Behar1,4,
Maria F. Pazyra-Murphy1,
Liliana Goumnerova5,
Keith L. Ligon6,
Charles D. Stiles1,
Rosalind A. Segal1
1Department of Cancer Biology, Dana-Farber Cancer Institute,
2Department of Pediatrics, Children's Hospital,
3Department of Biostatistics & Computational Biology, Dana-Farber Cancer Institute,
4Department of Developmental Biology and Cancer Research, Hebrew University of Jerusalem,
5Department of Neurosurgery, Children's Hospital,
6Center for Molecular Oncologic Pathology, Department of Medical Oncology, Dana-Farber Cancer Institute
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