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Rhode Island Hospital and The Warren Alpert School of Medicine of Brown University

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.

Meredith J. Crane¹, William L. Henry Jr¹, Holly L. Tran¹, Jorge E. Albina², Amanda M. Jamieson¹

¹Department of Molecular Microbiology & Immunology, Brown University, ²Division of Surgical Research, Department of Surgery, Rhode Island Hospital and The Warren Alpert School of Medicine of Brown University

Here, two murine wound healing models are described, one designed to assess cellular and cytokine wound healing responses and the other to quantify the rate of wound closure. These methods can be used with complex disease models such as diabetes to determine mechanisms of various aspects of poor wound healing.