Protocol for Developing a Femur Osteotomy Model in Wistar Albino RatsAayush Aryal 1, Pawan Kumar Pagaku 2, Devanjan Dey 2, Sagar Tyagi 2, Vadanya Shrivastava 2, Aditi Bhattacharya 2, Sweety Rani 2, Debdatta Nayak 6, Anil Khurana 6, Puneet Khanna 3, Ankur Goyal 4, Asit Ranjan Mridha 5, Bhavuk Garg 1, Sudip Sen 2
1Department of Orthopedics, All India Institute of Medical Sciences (AIIMS), 2Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), 3Department of Anaesthesiology Pain Medicine and Critical Care, All India Institute of Medical Sciences (AIIMS), 4Department of Radiodiagnosis, All India Institute of Medical Sciences (AIIMS), 5Department of Pathology, All India Institute of Medical Sciences (AIIMS), 6Central Council for Research in Homoeopathy (CCRH)
Here, we present a protocol to iatrogenically fracture the shaft of the femur of Wistar albino rats and follow up on the development of the callus. This femur osteotomy model can help researchers evaluate the process of fracture healing and to study how a drug could influence fracture healing.
